2-(Aminomethyl)-1-ethylpyrrolidine

Product Name: 2-(Aminomethyl)-1-ethylpyrrolidine
CAS No.: 26116-12-1
Chemical Name: 2-(Aminomethyl)-1-ethylpyrrolidine
Synonyms: Sulpiride impurity A CRS;Amisulpride EP Impurity A;1-ethylpyrrolidin-2-ylmethylamine;)-1-ethyL;Refer to S-402;Sulpiride EP Impurity A;Sulpiride Impurity A(EP);1-Ethyl-2-pyrrolidinemethylamine;n-ethyl-2-methylaminopyrrolidine;N-ETHYL-2-AMINOMETHYLPYRROLIDINE
CBNumber: CB5307995
Molecular Formula: C7H16N2
Formula Weight: 128.22
MOL File: 26116-12-1.mol

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2-(Aminomethyl)-1-ethylpyrrolidine Property

Boiling point:: 58-60 °C16 mm Hg(lit.)
Density: 0.884 g/mL at 25 °C(lit.)
refractive index: n20/D 1.4670(lit.)
Flash point:: 135 °F
storage temp.: 2-8°C
solubility: Chloroform (Sparingly), Methanol (Sparingly)
pka: 10.04±0.40(Predicted)
form: Liquid
color: Clear yellow
InChI: InChI=1S/C7H16N2/c1-2-9-5-3-4-7(9)6-8/h7H,2-6,8H2,1H3
InChIKey: UNRBEYYLYRXYCG-UHFFFAOYSA-N
SMILES: N1(CC)CCCC1CN
LogP: 0.433 (est)
CAS DataBase Reference: 26116-12-1(CAS DataBase Reference)
NIST Chemistry Reference: 2-Pyrrolidinemethanamine, 1-ethyl-(26116-12-1)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-20/21/22
Safety Statements: 26-36
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
HazardClass: 3.2
PackingGroup: III
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H226Flammable liquid and vapour

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 655600
Product name: 2-(Aminomethyl)-1-ethylpyrrolidine
Purity: 97%
Packaging: 5g
Price: $82.09
Updated: 2025/07/31

Sigma-Aldrich

Product number: S2191000
Product name: Sulpiride impurity A
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 20 mg
Price: $225
Updated: 2025/07/31

Sigma-Aldrich

Product number: 655600
Product name: 2-(Aminomethyl)-1-ethylpyrrolidine
Purity: 97%
Packaging: 25g
Price: $488
Updated: 2025/07/31

TCI Chemical

Product number: A2556
Product name: 2-(Aminomethyl)-1-ethylpyrrolidine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $43
Updated: 2025/07/31

TCI Chemical

Product number: A2556
Product name: 2-(Aminomethyl)-1-ethylpyrrolidine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $125
Updated: 2025/07/31

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2-(Aminomethyl)-1-ethylpyrrolidine Chemical Properties,Usage,Production

Chemical Properties

clear yellow liquid

Uses

2-(Aminomethyl)-1-ethylpyrrolidine is used as a reagent in the synthesis of S-Desethyl S-Methyl Amisulpride (D289595)

Synthesis

2167-14-8

26116-12-1

General procedure for the synthesis of N-ethyl-2-aminomethylpyrrolidine from 1-ethyl-1H-pyrrole-2-carboxaldehyde: 60 g of 1-ethyl-1H-pyrrole-2-carboxaldehyde was added to an autoclave, and 5 g of palladium-carbon catalyst at a mass percent concentration of 5% and 15 g of liquid ammonia were added to carry out hydrogenation and reductive amination reactions. The reaction conditions were hydrogen pressure of 35 kg and temperature of 95°C. After completion of the reaction, the system was cooled, the gas was expelled, and filtration was carried out. The filter cake was washed with methanol, and the filtrate and washings were combined to recover methanol. Finally, the target product N-ethyl-2-aminomethylpyrrole was obtained by purification via decompression distillation in a yield of 53.7 g and 86%. The reaction equation was as follows:

References

[1] Patent: CN107973735, 2018, A. Location in patent: Paragraph 0017; 0027-0029

2-(Aminomethyl)-1-ethylpyrrolidine Preparation Products And Raw materials

Raw materials

N,N-Dimethylformamide Tetrahydrofurfuryl alcohol

Preparation Products

Remoxipride Levosulpiride

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2-(Aminomethyl)-1-ethylpyrrolidine Suppliers

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View Lastest Price from 2-(Aminomethyl)-1-ethylpyrrolidine manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-(Aminomethyl)-1-ethylpyrrolidine 26116-12-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-04-12

Henan Aochuang Chemical Co.,Ltd.

Product: 2-(Aminomethyl)-1-ethylpyrrolidine 26116-12-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-10-13

Shaanxi Dideu Medichem Co. Ltd

Product: 2-(Aminomethyl)-1-ethylpyrrolidine 26116-12-1
Price: US $1.00-1.00/KG
Min. Order: 160KG
Purity: 99.0%GC
Supply Ability: 2000tons
Release date: 2021-03-09

26116-12-1, 2-(Aminomethyl)-1-ethylpyrrolidineRelated Search:

2,5-Dimethylpyrrolidine Hexamethyldisilazane Pyrrolidine Ethyl acrylate Ethylparaben CHLOROETHANE 1-Methylpyrrolidine N-Methyl-2-pyrrolidone Ethyl formate Ethylbenzene Ethyl cellulose Ethyl acetate Ethanol METHYL-2-PYRROLIDONE Actinomycin D N-Acetyl-L-prolinamide (R)-(+)-2-AMINOMETHYL-1-ETHYLPYRROLIDINE Diethyl ether

(1-Ethyl-2-pyrrolidinyl)methanamine

1-Ethyl-2-(aminomethyl)pyrrolidine

1-Ethyl-2-pyrrolidinemethylamine

2-(Aminomethyl)-N-ethylpyrrolidine

AMisulpride IMpurity A (Sulpiride IMpurity A)

Sulpiride IMpurity A (AMisulpride IMpurity A)

Pyrrolidine, 2-(aminomethyl)-1-ethyl-

2-(Aminomethyl)-1-ethylpyrrolidine 97%

Sulpiride Impurity A(EP)

[(2RS)-1-ethylpyrrolidin-2- yl]methanamine

Sulpiride Impurity 1（Sulpiride EP Impurity A）

N-Ethyl-2-Aminomethyl Pirrolidine

Sulpiride EP Impurity A

Amisulpride Impurity 1（Amisulpride EP Impurity A)

Amisulpride EP Impurity A

2-(AMINOMETHYL)-1-ETHYLPYRROLIDINE

2-PYRROLIDINEMETHANAMINE, 1-ETHYL-, (2S)-

n-ethyl-2-methylaminopyrrolidine

N-ETHYL-2-AMINOMETHYLPYRROLIDINE

N-ETHYL-ALPHA-AMINOMETHYL PYRROLIDINE

S(-)-1-ETHYL-2-(AMINOMETHYL)PYRROLIDINE

S-(-)N-ETHYL-A-AMINOMETHYL-PYRROLIDINE

S-(-)-N-ETHYL-ALPHA-(AMINOMETHYL)PYRROLIDINE

2-(Aminomethyl)-1-ethylpyrrolidine/N-ethyl-2-aminomethyl pyrrolidine

N-Ethyl-2-Aminoethyl Pyrrolidine

1-ethylpyrrolidin-2-ylmethylamine

S-(-)N-METHYL-A-AININOMETHYL-PYPROLIDINE

[(1-Ethyl-2-pyrrolidinyl)methyl]amine

1-Ethylpyrrolidine-2-methanamine

2-(Aminomethyl)-1-ethylpyrrolidine,95%

C-(1-Ethyl-pyrrolidin-2-yl)-methylamine

2-(AMinoMethyl)-1-ethylpyrrolidine, 95% 10GR

2-(AMinoMethyl)-1-ethylpyrrolidine, 95% 50GR

N-Ethyl-2-aMinoMethyl pyrrollidine

2-PyrrolidineMethanaMine,1-ethyl-

(2RS)-1-[ETHYLPYRROLIDINE-2-YL]-METHANAMINE

Amisulpride EP Impurity A (Sulpiride EP Impurity A)

Sulpiride EP Impurity A (Amisulpride EP Impurity A)

2-(Aminomethyl)-1-ethylpyrrolidine (26116-12-1)

2-(Aminomethyl)-1-ethylpyrrolidine (CAS : 26116-12-1)

2-(Aminomethyl)-1-ethylpyrrolidine &gt

[(2RS)-1-Ethylpyrrolidin-2-yl]metha

Sulpiride impurity A CRS

)-1-ethyL

1-Ethyl-2-aminomethyl pyrrolidine (EAP)

Amisulpride EP impurity AQ: What is Amisulpride EP impurity A Q: What is the CAS Number of Amisulpride EP impurity A Q: What is the storage condition of Amisulpride EP impurity A Q: What are the applications of Amisulpride EP impurity A

a . [(2RS)-1-e th ylpyrroli d i n-2-yl]me th a na mi ne ,

(Z)-[5-fluoro-2-methyl-1-[4-methylsulfanyl)benzylidene]-1H-inden-3-yl]acetic acid

Refer to S-402

N-ETHYL-2-AMINOMETHYL PYRROLIDINE (OTHER DETAIL AS PER INVOICE)

2-(Aminomethyl)-1-ethylpyrrolidine - [A15585]

2-(Aminomethyl)-1-Ethylpyrrolidine 2-()-1-

26116-12-1

26161-12-1

C7H16N2

Pyrrolidines

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