3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER
- Product Name
- 3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER
- CAS No.
- 22235-25-2
- Chemical Name
- 3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER
- Synonyms
- METHYL 3-AMINO-5-(TRIFLUOROMETHYL)BENZOATE;BUTTPARK 88\11-03;3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER;Benzoic acid, 3-amino-5-(trifluoromethyl)-, methyl ester
- CBNumber
- CB5313657
- Molecular Formula
- C9H8F3NO2
- Formula Weight
- 219.16
- MOL File
- 22235-25-2.mol
3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Appearance
- Light brown to light yellow Solid
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H227Combustible liquid
H315Causes skin irritation
H319Causes serious eye irritation
H341Suspected of causing genetic defects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- M331418
- Product name
- Methyl3-Amino-5-(trifluoromethyl)benzoate
- Packaging
- 50mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- PC901522
- Product name
- Methyl3-amino-5-(trifluoromethyl)benzoate
- Purity
- 97%
- Packaging
- 5g
- Price
- $235
- Updated
- 2021/12/16
- Product number
- W4584
- Product name
- Methyl3-amino-5-(trifluoromethyl)benzoate
- Packaging
- 5g
- Price
- $291
- Updated
- 2021/12/16
- Product number
- PC901522
- Product name
- Methyl3-amino-5-(trifluoromethyl)benzoate
- Purity
- 97%
- Packaging
- 10g
- Price
- $378
- Updated
- 2021/12/16
- Product number
- HCH0054582
- Product name
- METHYL 3-AMINO-5-(TRIFLUOROMETHYL)BENZOATE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $492
- Updated
- 2021/12/16
3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER Chemical Properties,Usage,Production
Synthesis
22227-63-0
22235-25-2
General procedure for the synthesis of methyl 3-amino-5-(trifluoromethyl)benzoate from methyl 3-nitro-5-trifluoromethylbenzoate: to a solution of methyl 3-nitro-5-(trifluoromethyl)benzoate (350 mg, 1.40 mmol) and tin(II) chloride dihydrate (1.58 g, 7.02 mmol) in methanol (20 mL) was added water (1 mL). The reaction mixture was stirred at 70 °C for 2 hours. After completion of the reaction, it was cooled to room temperature, the reaction solution was concentrated and quenched with saturated sodium bicarbonate solution. The reaction mixture was extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated to afford methyl 3-amino-5-(trifluoromethyl)benzoate (300 mg, 98% yield) as a colorless solid.1H NMR (400 MHz, CDCl3): δ 7.65 (s, 1H), 7.48 (s, 1H), 7.05 (s, 1H), 3.99 (br s, 2H), 3.91 (s, 3H).
References
[1] Patent: WO2012/37132, 2012, A1. Location in patent: Page/Page column 47
[2] Patent: WO2007/4749, 2007, A1. Location in patent: Page/Page column 125
[3] Patent: US2012/71489, 2012, A1. Location in patent: Page/Page column 59
[4] Patent: US2007/249607, 2007, A1. Location in patent: Page/Page column 72
[5] Patent: WO2008/9435, 2008, A1. Location in patent: Page/Page column 159; 160
3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER manufacturers
- Product
- 3-AMINO-5-TRIFLUOROMETHYL-BENZOIC ACID METHYL ESTER 22235-25-2
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2019-12-24