ChemicalBook > CAS DataBase List > tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate

Product Name
tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
CAS No.
1454848-24-8
Chemical Name
tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
Synonyms
EOS-60599;1-methyl-3-[(N-methyl-N-boc-amino)methyl]-1H-pyrzole-5-methannitrile;ert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate;tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate;tert-butyl N-[(4-bromo-5-cyano-1-methylpyrazol-3-yl)methyl]-N-methylcarbamate;TERT-BUTYL N-[(4-BROMO-5-CYANO-1-METHYL-1H-PYRAZOL-3-YL)METHYL]-N-METHYLCARBAMATE;Carbamic acid, N-[(4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl]-N-methyl-, 1,1-dimethylethyl ester
CBNumber
CB53143118
Molecular Formula
C12H17BrN4O2
Formula Weight
329.19
MOL File
1454848-24-8.mol
More
Less

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Property

Boiling point:
441.1±45.0 °C(Predicted)
Density 
1.38±0.1 g/cm3(Predicted)
storage temp. 
Store at 0-8 °C
pka
-1.77±0.70(Predicted)
InChI
InChI=1S/C12H17BrN4O2/c1-12(2,3)19-11(18)16(4)7-8-10(13)9(6-14)17(5)15-8/h7H2,1-5H3
InChIKey
XXLRKGVZBYVBNQ-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)N(CC1C(Br)=C(C#N)N(C)N=1)C
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Chemical Properties,Usage,Production

Uses

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate is a pharmaceutical intermediate compound that can be used in the synthetic anticancer prescription drug Lorlatinib. Lorlatinib is a drug used in the treatment of non-small cell lung cancer caused by adult non-small cell lung cancer (NSCLC) caused by an unusual mesenchymal lymphoma.

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate Suppliers

Shanghai Hope Chem Co., Ltd.,
Tel
+21-18501659228 18501659228
Fax
sales@hope-chem.com
Email
info@hope-chem.com
Country
China
ProdList
474
Advantage
55
Hangzhou Chemtrue Bio-Tech Co.,Ltd.
Tel
0571-86828652 18857119830
Fax
0571-83522824
Email
sales@chemtrue-bio.com
Country
China
ProdList
252
Advantage
58
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
28-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
510
Advantage
57
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
Tel
0512-68780025 18962125825
Email
sales@ryanchem.com
Country
China
ProdList
167
Advantage
62
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
993
Advantage
62
Syncozymes (Shanghai) Co.,Ltd.
Tel
021-68187180 13681683526
Fax
021-68187179
Email
lchen@syncozymes.com
Country
China
ProdList
317
Advantage
55
Suzhou Sino Rare Chemical Co., Ltd.
Tel
0512-62857507
Fax
+86-512-62857507
Email
sales@sinorarechem.com
Country
China
ProdList
991
Advantage
58
Beijin Yangguang Furui Chemical co.,Ltd.
Tel
010-57495520 13521095525
Email
zhw512@foxmail.com
Country
China
ProdList
488
Advantage
55
Shanghai YuanQi Biotechnology Co., Ltd.
Tel
+86-2332782371 +86-18120098618
Email
sales@adobechem.com
Country
China
ProdList
1250
Advantage
50
Lianyungang TengFa Biological Technology Co. Ltd
Tel
0518-85475186 18705131893
Fax
0518-85475186
Email
wang666xt@163.com
Country
China
ProdList
351
Advantage
55
More
Less

View Lastest Price from tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate manufacturers

Jinan Ruitong Biotech Co., Ltd.
Product
tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate 1454848-24-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1
Release date
2025-08-28
Henan Aochuang Chemical Co.,Ltd.
Product
tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate 1454848-24-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08
Nanjing Fred Technology Co., Ltd
Product
tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate 1454848-24-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2023-12-29

1454848-24-8, tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamateRelated Search:


  • tert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
  • EOS-60599
  • TERT-BUTYL N-[(4-BROMO-5-CYANO-1-METHYL-1H-PYRAZOL-3-YL)METHYL]-N-METHYLCARBAMATE
  • Carbamic acid, N-[(4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl]-N-methyl-, 1,1-dimethylethyl ester
  • tert-butyl N-[(4-bromo-5-cyano-1-methylpyrazol-3-yl)methyl]-N-methylcarbamate
  • 1-methyl-3-[(N-methyl-N-boc-amino)methyl]-1H-pyrzole-5-methannitrile
  • ert-butyl((4-bromo-5-cyano-1-methyl-1H-pyrazol-3-yl)methyl)(methyl)carbamate
  • 1454848-24-8