PGD2-inhibitor

Product Name: PGD2-inhibitor
CAS No.: 885066-67-1
Chemical Name: PGD2-inhibitor
Synonyms: MDK66671;PGD2-IN-1;PGD2-inhibitor;PGD2 inhibitor 1;PGD2-IN-1?, >98%;PGD2-inhibitor, >98%;PGD2-IN-1, 10 mM in DMSO;prostaglandin D2(PGD2) inhibitor;2-[3-(6-{[2-(2,4-dichlorophenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)phenyl]-2-methylpropanoic acid;Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl-
CBNumber: CB53146427
Molecular Formula: C23H23Cl2N3O3
Formula Weight: 460.35
MOL File: 885066-67-1.mol

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PGD2-inhibitor Property

Boiling point:: 682.1±65.0 °C(Predicted)
Density: 1.326±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 25 mg/mL (54.31 mM)
form: Solid
pka: 4.09±0.10(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals

Product number: DC9867
Product name: prostaglandinD2（PGD2)inhibitor
Purity: >98%
Packaging: 10mg
Price: $300
Updated: 2021/12/16

DC Chemicals

Product number: DC9867
Product name: prostaglandinD2（PGD2)inhibitor
Purity: >98%
Packaging: 25mg
Price: $450
Updated: 2021/12/16

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PGD2-inhibitor Chemical Properties,Usage,Production

Biological Activity

PGD2-IN-1 is a DP receptor antagonist from patent patent WO 2006044732 A2, compound example 15 (d) with IC50 value of 0.3 nM.

in vitro

Prostaglandin D2 (PGD2) is a major inflammatory mediator implicated in asthma and allergic rhinitis. It is largely produced as the major cyclooxygenase metabolite upon allergen-provoked degranulation from mast cells. Blockage of PGD2 using DP antagonists has been shown to be effective at alleviating the symptoms of allergic rhinitis in multiple species and more specifically has been shown to inhibit the antigen-induced nasal congestion.

target

IC50: 0.3 nM

PGD2-inhibitor Preparation Products And Raw materials

Raw materials

Preparation Products

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PGD2-inhibitor Suppliers

China 35 United States 3 USA 1 Global 39

Shanghai JiYi Biotechnology Co. Ltd.

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885066-67-1, PGD2-inhibitorRelated Search:

PGD2-inhibitor

PGD2-IN-1

MDK66671

PGD2-IN-1?, >98%

PGD2-inhibitor, >98%

prostaglandin D2(PGD2) inhibitor

PGD2 inhibitor 1

Benzeneacetic acid, 3-[6-[[2-(2,4-dichlorophenyl)ethyl]amino]-2-methoxy-4-pyrimidinyl]-α,α-dimethyl-

2-[3-(6-{[2-(2,4-dichlorophenyl)ethyl]amino}-2-methoxypyrimidin-4-yl)phenyl]-2-methylpropanoic acid

PGD2-IN-1, 10 mM in DMSO

885066-67-1