ChemicalBook > CAS DataBase List > CONDURITOL B EPOXIDE

CONDURITOL B EPOXIDE

Product Name
CONDURITOL B EPOXIDE
CAS No.
6090-95-5
Chemical Name
CONDURITOL B EPOXIDE
Synonyms
CBE;conduritolepoxide;CONDURITOL C EPOXIDE;CONDURITOL B EPOXIDE;1,2-Anhydro-myo-inositol;Myo-Inositol,1,2-anhydro-;(+/-) CONDURITOL B EPOXIDE;Conduritol B Epoxide (CBE);DL-1,2-ANHYDRO-MYO-INOSITOL;myo-Inositol, 1,2-anhydro- (9CI)
CBNumber
CB5316315
Molecular Formula
C6H10O5
Formula Weight
162.14
MOL File
6090-95-5.mol
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CONDURITOL B EPOXIDE Property

Melting point:
157-159
Boiling point:
360.5±42.0 °C(Predicted)
Density 
1.925±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
solubility 
Soluble in Water (up to 25 mg/ml) or in DMSO
pka
13.08±0.70(Predicted)
form 
White solid
color 
White
Stability:
Moisture Sensitive
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Safety

WGK Germany 
3
Hazard Note 
Harmful
HS Code 
2932990090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
234599
Product name
Conduritol B Epoxide
Packaging
100mg
Price
$403
Updated
2024/03/01
Sigma-Aldrich
Product number
C5424
Product name
Conduritol B epoxide
Packaging
5MG
Price
$163
Updated
2023/06/20
Sigma-Aldrich
Product number
C5424
Product name
Conduritol B epoxide
Packaging
25MG
Price
$556
Updated
2023/06/20
Cayman Chemical
Product number
15216
Product name
Conduritol B epoxide
Purity
≥95%
Packaging
5mg
Price
$54
Updated
2024/03/01
Cayman Chemical
Product number
15216
Product name
Conduritol B epoxide
Purity
≥95%
Packaging
25mg
Price
$155
Updated
2024/03/01
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CONDURITOL B EPOXIDE Chemical Properties,Usage,Production

Description

Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4.

Chemical Properties

White Crystalline Solid

Uses

inhibitor of glucosidases

Definition

ChEBI: 1-D-1,2-anhydro-myo-inositol is a conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B. It has a role as an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor and an EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor. It is functionally related to a (+)-conduritol B. It is an enantiomer of a 1-L-1,2-anhydro-myo-inositol.

General Description

Conduritol B epoxide?(CBE) is a mix of 1-L-1,2-anhydro-myo-inositol and 1-D-1,2-anhydro-myo-inositol.

Biochem/physiol Actions

Conduritol B epoxide?(CBE)?is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson′s disease (PD).

storage

Store at -20°C

References

1) Datta and Radin (1988), Normalization of liver glucosylceramide levels in the “Gaucher” mouse by phosphatidylserine injection;? Biochem. Biophys. Res. Commun., 152 155 2) Radin and Vunnam (1981), Inhibitors of cerebroside metabolism;? Methods Enzymol., 72 673 3) Stephens et al. (1981), Distribution of conduritol B epoxide in the animal model for gaucher’s disease (Gaucher mouse); Biochim. Biophys. Acta, 672 29 4) Newburg et al. (1986), beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell;? Biochim. Biophys. Acta, 877 121

CONDURITOL B EPOXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CONDURITOL B EPOXIDE Suppliers

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View Lastest Price from CONDURITOL B EPOXIDE manufacturers

Wuhan Topule Biopharmaceutical Co., Ltd
Product
Conduritol B Epoxide (Conduritol Epoxide) 6090-95-5
Price
US $10.00/g
Min. Order
1g
Purity
98%+
Supply Ability
2kg
Release date
2023-06-13

6090-95-5, CONDURITOL B EPOXIDERelated Search:

GW9508 Sodium 4-phenylbutyrate 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Glibenclamide L-ALPHA-PHOSPHATIDYLINOSITOL D-chiro-inositol CONDURITOL B CONDURITOL B EPOXIDE CIS,CIS-1,3,5-CYCLOHEXANETRIOL DIHYDRATE HEXAMETHYLENE OXIDE Cyclohexene oxide

  • Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem
  • CONDURITOL C EPOXIDE
  • conduritolepoxide
  • CBE
  • (+/-) CONDURITOL B EPOXIDE
  • CONDURITOL B EPOXIDE
  • DL-1,2-ANHYDRO-MYO-INOSITOL
  • 1,2-Anhydro-myo-inositol
  • (1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol
  • myo-Inositol, 1,2-anhydro- (9CI)
  • 4h-3,1-benzoxazin-4-one, 5-methyl-2-(3-nitrophenyl)-
  • Conduritol B Epoxide (CBE)
  • Myo-Inositol,1,2-anhydro-
  • (1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetraol
  • inhibit,Glucosidase,Inhibitor,Conduritol B epoxide
  • Conduritol B Epoxide (Conduritol Epoxide)
  • rel-(1R,2R,3S,4S,5R,6S)-7-Oxabicyclo[4.1.0]heptane-2,3,4,5-tetraol
  • Conduritol B Epoxide (Conduritol Epoxide), beta-glucosidase inhibitor
  • 6090-95-5
  • BioChemical
  • Biochemicals and Reagents
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Enzyme
  • Enzyme Inhibitors
  • D to K
  • Glucosidase, beta-
  • api
  • EPOXYDE
  • All Inhibitors
  • Glycosidase Inhibitors
  • Inhibitors