CONDURITOL B EPOXIDE

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CONDURITOL B EPOXIDE

Product Name: CONDURITOL B EPOXIDE
CAS No.: 6090-95-5
Chemical Name: CONDURITOL B EPOXIDE
Synonyms: CBE;conduritolepoxide;CONDURITOL C EPOXIDE;CONDURITOL B EPOXIDE;1,2-Anhydro-myo-inositol;Myo-Inositol,1,2-anhydro-;(+/-) CONDURITOL B EPOXIDE;Conduritol B Epoxide (CBE);DL-1,2-ANHYDRO-MYO-INOSITOL;myo-Inositol, 1,2-anhydro- (9CI)
CBNumber: CB5316315
Molecular Formula: C6H10O5
Formula Weight: 162.14
MOL File: 6090-95-5.mol

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CONDURITOL B EPOXIDE Property

Melting point:: 157-159
Boiling point:: 360.5±42.0 °C(Predicted)
Density: 1.925±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.: 2-8°C
solubility: Soluble in Water (up to 25 mg/ml) or in DMSO
pka: 13.08±0.70(Predicted)
form: White solid
color: White
Stability:: Moisture Sensitive

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Safety

WGK Germany: 3
Hazard Note: Harmful
HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 234599
Product name: Conduritol B Epoxide
Packaging: 100mg
Price: $403
Updated: 2024/03/01

Sigma-Aldrich

Product number: C5424
Product name: Conduritol B epoxide
Packaging: 5MG
Price: $163
Updated: 2023/06/20

Sigma-Aldrich

Product number: C5424
Product name: Conduritol B epoxide
Packaging: 25MG
Price: $556
Updated: 2023/06/20

Cayman Chemical

Product number: 15216
Product name: Conduritol B epoxide
Purity: ≥95%
Packaging: 5mg
Price: $54
Updated: 2024/03/01

Cayman Chemical

Product number: 15216
Product name: Conduritol B epoxide
Purity: ≥95%
Packaging: 25mg
Price: $155
Updated: 2024/03/01

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CONDURITOL B EPOXIDE Chemical Properties,Usage,Production

Description

Conduritol B epoxide (6090-95-5) is a β-Glycosidase inhibitor.1,2 May be used for generation of the “Gaucher mouse”3 and the in vitro model of the Gaucher cell4.

Chemical Properties

White Crystalline Solid

Uses

inhibitor of glucosidases

Definition

ChEBI: 1-D-1,2-anhydro-myo-inositol is a conduritol epoxide resulting from the formal epoxidation of the double bond of (+)-conduritol B. It has a role as an EC 3.2.1.48 (sucrose alpha-glucosidase) inhibitor and an EC 3.2.1.10 (oligo-1,6-glucosidase) inhibitor. It is functionally related to a (+)-conduritol B. It is an enantiomer of a 1-L-1,2-anhydro-myo-inositol.

General Description

Conduritol B epoxide?(CBE) is a mix of 1-L-1,2-anhydro-myo-inositol and 1-D-1,2-anhydro-myo-inositol.

Biochem/physiol Actions

Conduritol B epoxide?(CBE)?is capable of inactivating sucrase-isomaltase irreversibly. It can be used to produce cell and animal models to study on Gaucher disease (GD) and Parkinson′s disease (PD).

storage

Store at -20°C

References

1) Datta and Radin (1988), Normalization of liver glucosylceramide levels in the “Gaucher” mouse by phosphatidylserine injection;? Biochem. Biophys. Res. Commun., 152 155 2) Radin and Vunnam (1981), Inhibitors of cerebroside metabolism;? Methods Enzymol., 72 673 3) Stephens et al. (1981), Distribution of conduritol B epoxide in the animal model for gaucher’s disease (Gaucher mouse); Biochim. Biophys. Acta, 672 29 4) Newburg et al. (1986), beta-Glucosidase inhibition in murine peritoneal macrophages by conduritol-B-epoxide: an in vitro model of the Gaucher cell;? Biochim. Biophys. Acta, 877 121

CONDURITOL B EPOXIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from CONDURITOL B EPOXIDE manufacturers

Wuhan Topule Biopharmaceutical Co., Ltd

Product: Conduritol B Epoxide (Conduritol Epoxide) 6090-95-5
Price: US $10.00/g
Min. Order: 1g
Purity: 98%+
Supply Ability: 2kg
Release date: 2023-06-13

6090-95-5, CONDURITOL B EPOXIDERelated Search:

GW9508 Sodium 4-phenylbutyrate 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Glibenclamide L-ALPHA-PHOSPHATIDYLINOSITOL D-chiro-inositol CONDURITOL B CONDURITOL B EPOXIDE CIS,CIS-1,3,5-CYCLOHEXANETRIOL DIHYDRATE HEXAMETHYLENE OXIDE Cyclohexene oxide

Conduritol B Epoxide - CAS 6090-95-5 - Calbiochem

CONDURITOL C EPOXIDE

conduritolepoxide

CBE

(+/-) CONDURITOL B EPOXIDE

CONDURITOL B EPOXIDE

DL-1,2-ANHYDRO-MYO-INOSITOL

1,2-Anhydro-myo-inositol

(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetrol

myo-Inositol, 1,2-anhydro- (9CI)

4h-3,1-benzoxazin-4-one, 5-methyl-2-(3-nitrophenyl)-

Conduritol B Epoxide (CBE)

Myo-Inositol,1,2-anhydro-

(1R,2R,3S,4S,5R,6S)-7-oxabicyclo[4.1.0]heptane-2,3,4,5-tetraol

inhibit,Glucosidase,Inhibitor,Conduritol B epoxide

Conduritol B Epoxide (Conduritol Epoxide)

rel-(1R,2R,3S,4S,5R,6S)-7-Oxabicyclo[4.1.0]heptane-2,3,4,5-tetraol

6090-95-5

BioChemical

Biochemicals and Reagents

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Enzyme

Enzyme Inhibitors

D to K

Glucosidase, beta-

api

EPOXYDE

All Inhibitors

Glycosidase Inhibitors

Inhibitors