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Aloin

Product Name
Aloin
CAS No.
1415-73-2
Chemical Name
Aloin
Synonyms
ALOIN A;BARBALOIN;Alion;Aoin;ALOIN;Alcoin;Barbalin;Darbaloin;ALOEPOWDER;Aloin ,98%
CBNumber
CB5322789
Molecular Formula
C21H22O9
Formula Weight
418.39
MOL File
1415-73-2.mol
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Aloin Property

Melting point:
148°C
Boiling point:
456.17°C (rough estimate)
Density 
1.3028 (rough estimate)
refractive index 
1.6230 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
pyridine: 50 mg/mL, clear, dark red
form 
Solid
pka
7.12±0.40(Predicted)
color 
Yellow needles from EtOH
biological source
Curacao aloe
BRN 
6077558
Stability:
Stable, but light sensitive. Incompatible with bases, strong oxidizing agents. Combustible.
InChIKey
AFHJQYHRLPMKHU-WEZNYRQKSA-N
SMILES
[C@@]1([H])([C@H]2[C@H](O)[C@H]([C@H](O)[C@@H](CO)O2)O)C2C=CC=C(O)C=2C(=O)C2=C(O)C=C(CO)C=C12 |&1:0,2,3,5,6,8,r|
LogP
0.944 (est)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
RTECS 
LZ6520000
F 
8
HS Code 
29329990
Toxicity
LDLo orl-cat: 500 mg/kg HBAMAK 4,1298,35
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89558
Product name
Aloin A
Purity
phyproof<SUP>&#174;</SUP> Reference Substance
Packaging
10 mg
Price
$277
Updated
2025/07/31
Sigma-Aldrich
Product number
1013727
Product name
Aloin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$371
Updated
2025/07/31
Sigma-Aldrich
Product number
50292
Product name
Aloin
Purity
analytical standard
Packaging
10mg
Price
$563
Updated
2022/05/15
Cayman Chemical
Product number
22435
Product name
Aloin
Purity
≥95%
Packaging
500mg
Price
$25
Updated
2021/12/16
Cayman Chemical
Product number
22435
Product name
Aloin
Purity
≥95%
Packaging
1g
Price
$48
Updated
2021/12/16
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Aloin Chemical Properties,Usage,Production

Chemical Properties

lemon yellow crystalline powder

Uses

Aloin is a naturally occurring substance found in various Aloe plant species. Aloin was originally used as a laxative in the treatment of constipation. Recent studies have investigated Aloin as an ant ineoplastic agent that enhances melanogenesis and transglutaminase activity.

Uses

Aloe exudant, used as a stimulant-laxative

Definition

ChEBI: A C-glycosyl compound that is beta-D-glucopyranose in which the anomeric hydroxy group is replaced by a 4,5-dihydroxy-2-(hydroxymethyl)-10-oxo-9,10-dihydroanthracen-9-yl moiety (the 9S d astereoisomer).

Biological Activity

Purgative activity in rats requires activation by Eubacterium sp. strain BAR or similar intestinal anaerobe, presumably by conversion to aloe-emodin anthrone.

Safety Profile

Poison by subcutaneous andintravenous routes. Moderately toxic by ingestion. Whenheated to decomposition it emits acrid smoke and fumes.A carthartic and purgative.

Purification Methods

Aloin forms the monohydrate as lemon yellow crystals on crystallisation from H2O (450g/1.5L) which has a lower m ~70-80o than the anhydrous substance. [Cahn & Simonsen J Chem Soc 2573 1932, Hay & Haynes J Chem Soc 3141 1956.]

Aloin Preparation Products And Raw materials

Raw materials

Preparation Products

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Aloin Suppliers

Canada 1 China 438 Europe 3 France 2 Germany 6 India 5 Japan 2 South Korea 1 Switzerland 2 United Kingdom 8 United States 37 USA 1 Global 506
Carl Roth offre
Tel
--
Fax
--
Email
r.eckert@rothsochiel.fr
Country
France
ProdList
2361
Advantage
58
Extrasynthese
Tel
--
Fax
--
Email
info@extrasynthese.com
Country
France
ProdList
1333
Advantage
64
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View Lastest Price from Aloin manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Aloin 1415-73-2
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-03
Changsha Staherb Natural Ingredients Co., Ltd.
Product
Aloin 1415-73-2
Price
US $0.00/kg
Min. Order
1kg
Purity
20%；50%；98% HPLC
Supply Ability
1000kg
Release date
2022-11-04
BINBO BIOLOGICAL CO.,LTD
Product
Aloin 1415-73-2
Price
US $0.00/kg
Min. Order
1kg
Purity
10%, 20%, 90%
Supply Ability
1000 kg
Release date
2024-05-10

1415-73-2, AloinRelated Search:

Emodin-3-methyl ether Aloe emodin Tris(hydroxymethyl)nitromethane Emodin Solvent Red 43 Aloin B ALOESIN 2,2'-DIHYDROXYBENZOPHENONE 1,1-DIPHENYLHEXANE 1,1-DIPHENYL-2-PROPANOL ALOIN,POWDER,ALOIN, CRUDE Ellagic acid Aloin 8-O-β-D-glucopyranoside 5-ISOPROPYL-3-METHYLPHENOL 3,3-Diphenylpropanol Aloin (R)-(-)-1,1-DIPHENYL-2-PROPANOL 2,5-DIMETHYLPHENETHYL ALCOHOL

  • barbaloin from aloe barbadensis*miller leaves
  • Barbaloin std.
  • BarbaloinStandard
  • 9(10H)-Anthracenone, 10-.beta.-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (10S)-
  • 1,8-dihydroxy-10-(β-d-glucopyranosyl)-3-(hydroxymethyl)-9(10h)-anthracenone
  • ALOIN A(BARBALOIN)(P)
  • ALOIN A(BARBALOIN)(SH)
  • ALOIN B(P)(NEW)
  • Aloe-saponol Aloin
  • AloinA, Barbaloin, 1,8-Dihydroxy-10-(β-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone, 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
  • Barbaloin，Aloin
  • 1,8-Dihydroxy-10-(b-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone
  • 10-b-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
  • (10S)-1,8-Dihydroxy-3-(hydroxymethyl)-10β-β-D-glucopyranosyl-9,10-dihydroanthracene-9-one
  • (S)-10-(β-D-Glucopyranosyl)-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one
  • 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone
  • ALOIN A&B (P)
  • (R)-10-beta-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)anthracen-9(10H)-one
  • Aloin/Barbaloin
  • ALOIN A WITH HPLC
  • ALOEPOWDER
  • Aloin,1,8-Dihydroxy-10-(β-D-glucopyranosyl)-3-(hydroxymethyl)-9(10H)-anthracenone, 10-β-D-Glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-9(10H)-anthracenone, AloinA, Barbaloin
  • Aloin ,98%
  • 9(10H)-Anthracenone, 10-β-D-glucopyranosyl-1,8-dihydroxy-3-(hydroxymethyl)-, (10S)-
  • Barbalin
  • Aloin/Baraloin
  • Aloin (25 mg)
  • Aoin
  • Darbaloin
  • Aloin, 99%, from Aloe L.
  • 1,8-dihydroxy-3-hydroxymethyl-10-(6-hydroxymethyl-3,4,5-trihydroxy-2-pyranyl
  • 10-(1’,5’-anhydroglucosyl)aloe-emodin-9-anthrone
  • 9(10h)-anthracenone-10-beta-d-glucopyranosyl-
  • BARBALOIN
  • 1,8-DIHYDROXY-10-(BETA-D-GLUCOPYRANOSYL)-3-(HYDROXYMETHYL)-9(10H)-ANTHRACENONE
  • Aloin, froM Aloe L.
  • 10-GLUCOPYRANOSYL-1,8-DIHYDRO-3-(HYDROXYMETHYL)-9-ANTHRACENONE
  • 10-BETA-D-GLUCOPYRANOSYL-1,8-DIHYDROXY-3-[HYDROXYMETHYL]-9[10H]-ANTHRACENONE
  • (10S)-BETA-D-GLUCOPYRANOSIDE-ALOE EMODIN
  • ALOIN
  • ALOIN A
  • ALOINS A AND B
  • Aloin, >=97%
  • Aloin, ≥96%
  • Aloin, ≥90%
  • Aloin,Barbaloin 1415-73-2
  • Aloin 18%-98%
  • Alion
  • Aloin USP/EP/BP
  • Natural Aloe Vera Extract Aloin Powder CAS?1415-73-2
  • (S)-1,8-Dihydroxy-3-(hydroxymethyl)-10-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)anthracen-9(10H)-one
  • (10R)-1,8-dihydroxy-3-(hydroxymethyl)-10-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-9,10-dihydroanthracen-9-one
  • Alcoin
  • Barbaloin (8CI)
  • ALOIN A(BARBALOIN)
  • Aloin A (25 mg) ((S)-10-Beta-D-Glucopyranosyl-1,8-dihydroxy-3-hydroxymethylanthracen-9(10H)-one)
  • Aloin A(P)
  • Aloin A(Barbaloin)(AS)