ChemicalBook > CAS DataBase List > 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one

2-Ethoxy-5-fluoro-1H-pyrimidin-4-one

Product Name
2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
CAS No.
56177-80-1
Chemical Name
2-Ethoxy-5-fluoro-1H-pyrimidin-4-one
Synonyms
5-EFV;ETHOXYFLUOROURACIL;Flucytosine Impurity B;2-ETHOXY-5-FLUOROURACIL;2-ethoxyl-5-fluorouracil;2-Hydroxy-5-fluorouracil;Fluorouracil EP ImpurityF;Fluorouracil BP Impurity F;Fluorouracil impurity F CRS;Fluorouracil Related CoMpound F
CBNumber
CB5323236
Molecular Formula
C6H7FN2O2
Formula Weight
158.13
MOL File
56177-80-1.mol
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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Property

Melting point:
180-184 °C (lit.)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
solid
pka
6.45±0.50(Predicted)
Appearance
White to off-white Solid
Water Solubility 
2g/L at 20℃
InChI
InChI=1S/C6H7FN2O2/c1-2-11-6-8-3-4(7)5(10)9-6/h3H,2H2,1H3,(H,8,9,10)
InChIKey
XREDGJFKPWBNRQ-UHFFFAOYSA-N
SMILES
C1(OCC)=NC=C(F)C(=O)N1
LogP
-0.96 at 25℃
CAS DataBase Reference
56177-80-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000765
Product name
Fluorouracil impurity F
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
10 mg
Price
$118
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR2868
Product name
Fluorouracil Related Compound F
Purity
certified reference material, pharmaceutical secondary standard
Packaging
50MG
Price
$593.75
Updated
2025/07/31
Sigma-Aldrich
Product number
559903
Product name
5-Fluoro-2-ethoxy-4(1H)pyrimidinone
Purity
97%
Packaging
25g
Price
$261.5
Updated
2025/07/31
Sigma-Aldrich
Product number
1279065
Product name
Fluorouracil Related Compound F
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1200
Updated
2025/07/31
TCI Chemical
Product number
E0684
Product name
2-Ethoxy-5-fluoro-4-pyrimidinone
Purity
>98.0%(GC)
Packaging
5g
Price
$77
Updated
2021/12/16
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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Chemical Properties,Usage,Production

Uses

Ethoxy-5-fluoro-4(3H)-pyrimidinone (Fluorouracil EP Impurity F) is a derivative of 5-fluorouracil (3C,15N2 labelled, F596002) which is a potent antineoplastic agent in clinical use.

2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Ethoxy-5-fluoro-1H-pyrimidin-4-one Suppliers

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View Lastest Price from 2-Ethoxy-5-fluoro-1H-pyrimidin-4-one manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
2-Ethoxy-5-fluoro-1H-pyrimidin-4-one 56177-80-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg
Release date
2021-10-28
Henan Aochuang Chemical Co.,Ltd.
Product
2-Ethoxy-5-fluoro-1H-pyrimidin-4-one 56177-80-1
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Shaanxi Dideu Medichem Co. Ltd
Product
2-Ethoxy-5-fluoro-4-pyrimidinone 56177-80-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-14

56177-80-1, 2-Ethoxy-5-fluoro-1H-pyrimidin-4-oneRelated Search:


  • ETHOXYFLUOROURACIL
  • 5-FLUORO-2-ETHOXY-4(1H)-PYRIMIDINONE
  • 5-FLUORO-2-ETHOXY-4-PYRIMIDINONE
  • 2-ethoxy-5-fluoro-1h-pyrimidin-4-one
  • 2-ETHOXY-5-FLUORO-2,3-DIHYDROPYRIMIDIN-4(1H)-ONE
  • 2-ETHOXY-5-FLUORO-4(3H)-PYRIMIDINONE
  • 2-ETHOXY-5-FLUORO-4-HYDROXYPYRIMIDINE
  • 2-ETHOXY-5-FLUORO-4-PYRIMIDINONE
  • 2-ETHOXY-5-FLUOROURACIL
  • 2-ethoxy-5-fluoropyrimidin-4(3H)-one
  • 2-ethoxyl-5-fluorouracil
  • 2-ETHOXY-5-FLUOROPYRIMIDIN-4(1H)-ONE
  • 2-Ethoxy-5-fluoro-pyrimidin-4-ol
  • 5-EFV
  • 2-Ethoxy-5-fluoro-4(1H)-pyrimidinone
  • 2-ethoxy-5-fluoro-1H-pyrimidin-6-one
  • 2-Ethoxy-5-fluoro-3H-pyrimidin-4-one
  • 2-ethoxy-5-fluoro-3,4-dihydropyriMidin-4-one
  • 5-Fluoro-2-ethoxy-4(1H)pyrimidinon
  • Fluorouracil Related CoMpound F
  • 4(3H)-Pyrimidinone,2-ethoxy-5-fluoro-
  • Fluorouracil Impurity 6(Fluorouracil EP Impurity F)
  • Fluorouracil EP ImpurityF
  • Fluorouracil BP Impurity F
  • Fluorouracil impurity F CRS
  • 2-Ethoxy-5-fluoro-4-pyrimidinone&gt
  • 2-ETHOXY-5-FLUORO-1H-PYRIMIDIN-4-ONE 56177-80-1
  • Fluorouracil Related Compound F (2-Ethoxy-5-fluoropyrimidin-4(1H)-one) (1279065)
  • Fluorouracil USP Related Compound F
  • Flucytosine Impurity B
  • 2-Ethoxy-5-fluoropyrimidin-4(1H)-one (2-Ethoxy-5-fluorouracil)
  • 5-Fluoro-2-ethoxy-4(1<i>H</i>)pyrimidinone
  • 2-Hydroxy-5-fluorouracil
  • Fluorouracil EP Impurity F(Flucytosine EP Impurity B)
  • 56177-80-1
  • C4N2H2FOOCH2CH3
  • C6H7FN2O2
  • Building Blocks
  • Pyrimidines
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Pyridines, Pyrimidines, Purines and Pteredines
  • INTERMEDIATESOFFINASTERIDE
  • Pyrimidine