Lanoconazole

ChemicalBook > CAS DataBase List > Lanoconazole

Product Name: Lanoconazole
CAS No.: 101530-10-3
Chemical Name: Lanoconazole
Synonyms: le;Astat;itrile;nnd-318;tjn-318;Lanocozole;latoconazole;LANOCONAZOLE;Lanoconazole USP/EP/BP;[4-(2-chloro-phenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile
CBNumber: CB5333996
Molecular Formula: C14H10ClN3S2
Formula Weight: 319.83
MOL File: 101530-10-3.mol

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Lanoconazole Property

Melting point:: 141.50C
Boiling point:: 477.6±55.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 3.76±0.10(Predicted)
color: White
CAS DataBase Reference: 101530-10-3(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
RTECS: NI3393500
Toxicity: LD50 in male, female mice, rats (mg/kg): 3224, 2715, 993, 652 orally; 2158, 1743, 1655, 2596 i.p.; >5000 both species s.c.; LD50 dermally in rats: >5000 mg/kg (Munt)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 32991
Product name: Lanoconazole
Purity: VETRANAL
Packaging: 25mg
Price: $94
Updated: 2024/03/01

TRC

Product number: L174500
Product name: Lanoconazole
Packaging: 100mg
Price: $600
Updated: 2021/12/16

AK Scientific

Product number: G613
Product name: Lanoconazole
Packaging: 5mg
Price: $49
Updated: 2021/12/16

ChemScene

Product number: CS-0003253
Product name: Lanoconazole
Purity: 98.48%
Packaging: 5mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-0003253
Product name: Lanoconazole
Purity: 98.48%
Packaging: 10mg
Price: $85
Updated: 2021/12/16

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Lanoconazole Chemical Properties,Usage,Production

Description

Lanoconazole is a potent antifungal imidazole launched in Japan for the treatment of dermal mycoses. Lanoconazole is reported to be an inhibitor of ergosterol biosynthesis thus altering the ultra structure of the cell wall. It exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., Penici//ium spp., and Candida spp., being particularly active against Trichophyton spp.. It is considerably more potent than other agents of the same family such as bifonazole and clotrimazole. Clinical efficacy was demonstrated by remarkable improvements in skin symptoms of the patients with tinea pedis, tinea corporis and cruis, candidiasis or tinea versicolor.

Chemical Properties

Light-Yellow Crystals

Originator

Nihon Nohyaku (Japan)

Uses

Antifungal.

Definition

ChEBI: Lanoconazole is a conazole antifungal drug and an imidazole antifungal drug.

brand name

Astat

Lanoconazole Preparation Products And Raw materials

Raw materials

Silica gel N,N-Dimethylformamide Potassium hydroxide Dipotassium rabdosiin Rabdosiin SULFATE STANDARD

Preparation Products

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View Lastest Price from Lanoconazole manufacturers

Dideu Industries Group Limited

Product: Lanoconazole 101530-10-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-16

Career Henan Chemical Co

Product: Lanoconazole 101530-10-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 200KG
Release date: 2019-08-30

101530-10-3, LanoconazoleRelated Search:

Tetraphenylcyclopentadienone Miconazole nitrate Phenyl salicylate Iminodiacetonitrile Dimethyl disulfide Itraconazole Selenium sulfide Fluconazole Diphenyl ether Imidazole PHENYL VALERATE Ketoconazole Voriconazole PHENYL RESIN Difluorochloromethane Benzeneacetonitrile Phenylacetic acid acetonitrile

LANOCONAZOLE

[4-(2-chloro-phenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

(+-)-(e)-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitri

(e)-alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-1h-imidazole-1-aceton

1h-imidazole-1-acetonitrile,alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)

(E)-alpha-(4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene)-1H-imidazole-1-acetonitrile

1H-Imidazole-1-acetonitrile, alpha-(4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene)-, (E)-(+-)

(E)-2-[4-(2-Chlorophenyl)-1,3-dithiolane-2-ylidene]-2-(1-imidazolyl)acetonitrile

itrile

latoconazole

nnd-318

tjn-318

(E)-(+/-)-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazole-1-acetonitrile

1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (aE)- (9CI)

1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-

1H-Imidazole-1-acetonitrile, a-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (E)-(+-)-

Astat

2-[4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-yl-acetonitrile

(+-)-(E)-(4-(2-Chlorophenyl)-1,3-dithiolan-2-ylidene)-1-imidazolylacetonitrile

Lanocozole

1H-Imidazole-1-acetonitrile, α-[4-(2-chlorophenyl)-1,3-dithiolan-2-ylidene]-, (αE)-

Lanoconazole USP/EP/BP

101530-10-3

C14H10ClN3S2

Intermediates & Fine Chemicals

Pharmaceuticals