Tetradecyltrimethylammonium bromide
Physical properties- Product Name
- Tetradecyltrimethylammonium bromide
- CAS No.
- 1119-97-7
- Chemical Name
- Tetradecyltrimethylammonium bromide
- Synonyms
- TTAB;Tetradecyltrimethylammonium bromide;MTAB;Tetradecyltrimethylammonium bromide;Tetradecyl trimethyl ammonium bromide;Myristyltrimethylammonium bromide;Tetradecanaminium,N,N,N-trimethyl-,bromide;1432;mytab;MitMAB
- CBNumber
- CB5335152
- Molecular Formula
- C17H38N.Br
- Formula Weight
- 336.39
- MOL File
- 1119-97-7.mol
Tetradecyltrimethylammonium bromide Property
- Melting point:
- 245-250 °C(lit.)
- Density
- 1.1328 (rough estimate)
- vapor pressure
- 0Pa at 25℃
- refractive index
- 1.5260 (estimate)
- storage temp.
- Store below +30°C.
- solubility
- H2O: 10 % (w/v)
- form
- Fine Crystalline Powder
- color
- White
- PH
- pH (50g/l, 25℃ : 4.0~6.0
- Water Solubility
- 20 g/100 mL
- Sensitive
- Hygroscopic
- λmax
- λ: 240 nm Amax: ≤0.08
λ: 250 nm Amax: ≤0.05
λ: 260 nm Amax: ≤0.04
λ: 500 nm Amax: ≤0.02 - Merck
- 14,6336
- BRN
- 3633227
- Stability:
- Stable. Hygroscopic. Incompatible with strong oxidizing agents.
- InChIKey
- CXRFDZFCGOPDTD-UHFFFAOYSA-M
- LogP
- 2.2 at 20℃
- CAS DataBase Reference
- 1119-97-7(CAS DataBase Reference)
- EPA Substance Registry System
- Tetradecyl trimethyl ammonium bromide (1119-97-7)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45-27
- RIDADR
- UN 3263 8/PG 2
- WGK Germany
- 3
- RTECS
- BS5776000
- F
- 3
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29239000
- Toxicity
- LD50 in mice, rats (mg/kg): 12.0, 15.0 i.v. (Issomaa, Bjondahl)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
H373May cause damage to organs through prolonged or repeated exposure
H400Very toxic to aquatic life
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P314Get medical advice/attention if you feel unwell.
N-Bromosuccinimide Price
- Product number
- 8.40006
- Product name
- Tetradecyltrimethylammonium bromide
- Purity
- forsynthesis
- Packaging
- 25g
- Price
- $30.8
- Updated
- 2024/03/01
- Product number
- 87208
- Product name
- Myristyltrimethylammonium bromide
- Purity
- for ion pair chromatography, ≥99.0% (AT)
- Packaging
- 10g
- Price
- $228
- Updated
- 2024/03/01
- Product number
- 8.40006
- Product name
- Tetradecyltrimethylammonium bromide
- Purity
- forsynthesis
- Packaging
- 100g
- Price
- $67.3
- Updated
- 2024/03/01
- Product number
- 324411
- Product name
- Dynamin Inhibitor II, MiTMAB
- Packaging
- 500mg
- Price
- $85.2
- Updated
- 2024/03/01
- Product number
- T0906
- Product name
- Tetradecyltrimethylammonium Bromide
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $18
- Updated
- 2024/03/01
Tetradecyltrimethylammonium bromide Chemical Properties,Usage,Production
Physical properties
Cetrimide is a white fine powder crystal with a melting point of 245°C to 250°C. A rough estimate of its density is 1.1328. It is soluble in water with a solubility of 20 g/100 mL.
Description
MiTMAB (1119-97-7) is a dynamin I/II inhibitor targeting the dynamin-phospholipid interaction and inhibiting dynamin GTPase activity with a Ki=940nM.1 Rapidly and reversibly inhibits multiple forms of endocytosis with no acute cellular damage1. A useful pharmacological tool for studying dynamin-mediated trafficking events.2 Induces cytokinesis failure and apoptosis in human cancer cells.3 Induces cytoprotective autophagy in human Jurkat T cells.4
Uses
Myristyltrimethylammonium has been used in a study to assess a surfactant-controlled synthetic method to obtain a nanophase of mesoporous ceria-zirconia solid solution containing cationic defects in the crystalline structure.??It has also been used in a study to determine the low molecular weight of organic acids in soils and plants by capillary zone electrophoresis.
Uses
Disinfectant; deodorant; laboratory reagent.
Definition
Myristyltrimethylammonium bro-mide.
General Description
Myristyltrimethylammonium bromide is a cationic/zwitterionic type of surfactant.
Purification Methods
Crystallise the bromide from acetone or a mixture of Me2CO and >5% MeOH or Me2CO/EtOH. Wash it with diethyl ether and dry it in a vacuum oven at 60o. It is a cationic detergent. Its solubility is 1g/5g H2O. [Dearden & Wooley J Phys Chem 91 2404 1987, Shelton et al. J Am Chem Soc 68 754 1946, Beilstein 4 III 419, 4 IV 813.]
References
1) Quan et al. (2007), Myristal trimethyl ammonium bromide and octadecyl trimethyl ammonium bromide are surface-active small molecules dynamin inhibitors that block endocytosis mediated by dynamin I or dynamin II; Mol. Pharmacol., 72 1425 2) Joshi et al. (2011), Development and validation of a stability indicating method for the enantioselective estimation of omeprazole enantiomers in the enteric-coated formulations by high performance liquid chromatography; Mol. Cancer, 104 78 3) De Beco et al. (2009), Endocytosis is required for E-cadherin redistribution at mature adherens junctions; Proc. Natl. Acad. Sci. USA, 106 7010 4) Kim et al. (2016), Inhibition of autophagy enhances dynamin inhibitor-induced apoptosis via promoting Bak activation and mitochondrial damage in human Jurkat T cells; Biochem. Biophys. Res. Commun., 478 1609
Tetradecyltrimethylammonium bromide Preparation Products And Raw materials
Raw materials
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View Lastest Price from Tetradecyltrimethylammonium bromide manufacturers
- Product
- Tetradecyltrimethylammonium bromide 1119-97-7
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- More than 99%
- Supply Ability
- 2000KG/MONTH
- Release date
- 2024-04-22
- Product
- Tetradecyltrimethylammonium bromide 1119-97-7
- Price
- US $5.00-0.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-13
- Product
- Tetradecyltrimethylammonium bromide 1119-97-7
- Price
- US $8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20000
- Release date
- 2024-01-08