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Aprepitant Impurity 9

Product Name
Aprepitant Impurity 9
CAS No.
219821-37-1
Chemical Name
Aprepitant Impurity 9
Synonyms
Aprepitant Impurity 9;Aprepitant Impurity 47;Fosaprepitant Impurity U;Aprepitant Open-Ring Methyl Ester Impurity;Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity;Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate;methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate;2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester;Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
CBNumber
CB53358992
Molecular Formula
C24H25F7N4O4
Formula Weight
566.47
MOL File
219821-37-1.mol
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Aprepitant Impurity 9 Property

Density 
1.43±0.1 g/cm3(Predicted)
solubility 
soluble in Chloroform, Dichloromethane, Methanol
form 
Solid
pka
7.86±0.43(Predicted)
color 
Pale-Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D297840
Product name
N-(Destriazolonomethyl)N-(Methylcarboxyacetamidohydrazono)Aprepitant
Packaging
10mg
Price
$1010
Updated
2021/12/16
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Aprepitant Impurity 9 Chemical Properties,Usage,Production

Uses

N-(Destriazolonomethyl), N-(Methylcarboxyacetamidohydrazono) Aprepitant is a derivative of Aprepitant (A729800), a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1.

Aprepitant Impurity 9 Preparation Products And Raw materials

Raw materials

Preparation Products

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Aprepitant Impurity 9 Suppliers

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219821-37-1, Aprepitant Impurity 9Related Search:


  • Aprepitant Impurity 9
  • Aprepitant Open-Ring Methyl Ester Impurity
  • 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]hydrazinecarboxylic acid methyl ester
  • Aprepitant impurity 22/Aprepitant Open-Ring Methyl Ester Impurity
  • Aprepitant Impurity 47
  • Methyl 2-(2-((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholino)-1-iminoethyl)hydrazinecarboxylate
  • Hydrazinecarboxylic acid, 2-[2-[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)-4-morpholinyl]-1-iminoethyl]-, methyl ester
  • methyl 2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
  • Fosaprepitant Impurity U
  • 219821-37-1
  • C24H25F7N4O4