wu

Product Name: wu
CAS No.: 1627929-55-8
Chemical Name: wu
Synonyms: CS-2690;PLX51107;PXL51107;PLX51109;PXL 51107 ;PXL-51107;PLX51107 (PLX 51107);PLX51107, 10 mM in DMSO;PLX51107;PLX 51107;PLX-51107;PLX 51107,Epigenetic Reader Domain,PLX51107,inhibit,PLX-51107,Inhibitor;4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic
CBNumber: CB53379667
Molecular Formula: C26H22N4O3
Formula Weight: 438.48
MOL File: 1627929-55-8.mol

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wu Property

Melting point:: >270°C (dec.)
Boiling point:: 683.3±55.0 °C(Predicted)
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: -20°C Freezer
solubility: DMSO (Slightly, Heated)
pka: 3.68±0.10(Predicted)
form: Solid
color: White to Off-White
InChIKey: AMSUHYUVOVCWTP-INIZCTEOSA-N
SMILES: C(O)(=O)C1=CC=C(C2C3=NC=C(C4=C(C)ON=C4C)C=C3N([C@H](C3=NC=CC=C3)C)C=2)C=C1

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: D468190
Product name: 4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoicAcid
Packaging: 1mg
Price: $140
Updated: 2021/12/16

TRC

Product number: D468190
Product name: 4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoicAcid
Packaging: 5mg
Price: $400
Updated: 2021/12/16

ChemScene

Product number: CS-0040568
Product name: PLX51107
Purity: 99.81%
Packaging: 5mg
Price: $150
Updated: 2021/12/16

ChemScene

Product number: CS-0040568
Product name: PLX51107
Purity: 99.81%
Packaging: 10mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0040568
Product name: PLX51107
Purity: 99.81%
Packaging: 50mg
Price: $950
Updated: 2021/12/16

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wu Chemical Properties,Usage,Production

Uses

4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic Acid, is a potent and selective BET inhibitor.

in vivo

PLX51107 (2 mg/kg, p.o.) inhibits splenomegaly by 75% in the Ba/F3 (murine IL3-dependent pro-B-cell line) splenomegaly mouse model, with the similar effect of 25 mg/kg OTX015. PLX51107 (20 mg/kg, qd, p.o.) exhibits potent antileukemic effects in disease models of aggressive chronic lymphocytic leukemia (CLL) and Richter transformation (RT) via oral administration once daily^[1].

wu Preparation Products And Raw materials

Raw materials

Preparation Products

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wu Suppliers

China 80 United States 5 Global 85

Fujian boshi pharmaceutical technology co. LTD

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Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

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Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
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Email: 3008007409@qq.com
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Shanghai Chaolan Chemical Technology Center

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1627929-55-8, wuRelated Search:

PLX8394 PLX-4720 PLX3397 (Pexidartinib) PLX5622 PLX3397 HCl

PLX51109

PXL51107

PLX51107

PLX51107;PLX 51107;PLX-51107

CS-2690

PXL 51107 ;PXL-51107

4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic Acid

Benzoic acid, 4-[6-(3,5-dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]-

PLX 51107,Epigenetic Reader Domain,PLX51107,inhibit,PLX-51107,Inhibitor

(S)-4-(6-(3,5-Dimethylisoxazol-4-yl)-1-(1-(pyridin-2-yl)ethyl)-1H-pyrrolo[3,2-b]pyridin-3-yl)benzoic acid

PLX51107, 10 mM in DMSO

PLX51107 (PLX 51107)

4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic

1627929-55-8