PLX8394

Product Name: PLX8394
CAS No.: 1393466-87-9
Chemical Name: PLX8394
Synonyms: PLX8394;plixorafenib;PLX8394,PLX-8394;PLX8394;PLX-8394;PLX 8394;(R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide;(R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide;1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-
CBNumber: CB83053926
Molecular Formula: C25H21F3N6O3S
Formula Weight: 542.53
MOL File: 1393466-87-9.mol

More

Less

PLX8394 Property

Density: 1.60±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 39 mg/mL (71.89 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 6.33±0.40(Predicted)
color: White to light yellow
InChIKey: YYACLQUDUDXAPA-MRXNPFEDSA-N
SMILES: N1(S(NC2=CC=C(F)C(C(C3C4=CC(C5=CN=C(C6CC6)N=C5)=CN=C4NC=3)=O)=C2F)(=O)=O)CC[C@@H](F)C1

More

Less

Safety

HS Code: 2935909099

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: BP168493
Product name: PLX 8394
Packaging: 10mg
Price: $85
Updated: 2021/12/16

AK Scientific

Product number: 3017EB
Product name: (3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging: 10mg
Price: $164
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BP168493
Product name: PLX 8394
Packaging: 50mg
Price: $297.5
Updated: 2021/12/16

AK Scientific

Product number: 3017EB
Product name: (3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging: 50mg
Price: $451
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573235
Product name: PLX8394
Purity: >98%
Packaging: 100mg
Price: $1208.7
Updated: 2021/12/16

More

Less

PLX8394 Chemical Properties,Usage,Production

Uses

Combination therapies comprising KRAS G12C inhibitors and Raf kinase inhibitors for treating KRAS G12C cancers.BRAF inhibitor.

PLX8394 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

PLX8394 Suppliers

China 63 India 1 United States 7 Global 71

ShangHai ChuanQian Chemcial Technique Centre

Tel: 15869524721
Email: 3525679403@qq.com
Country: China
ProdList: 4012
Advantage: 58

Hunan Huayi Zhide Pharmaceutical Technology Co., Ltd.

Tel: 17752881701
Email: 190060276@qq.com
Country: China
ProdList: 111
Advantage: 58

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 17702719238
Email: sales@sun-shinechem.com
Country: China
ProdList: 985
Advantage: 64

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19179
Advantage: 64

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4573
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27313
Advantage: 60

Changzhou PBpharmaceutical R&D Co.,Ltd

Tel: 0519-83990708
Fax: 0519-83990708
Email: lxy2046@yeah.net
Country: China
ProdList: 476
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8011
Advantage: 62

More

Less

View Lastest Price from PLX8394 manufacturers

Career Henan Chemical Co

Product: PLX8394 1393466-87-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-26

1393466-87-9, PLX8394Related Search:

PLX-4720 wu PLX3397 (Pexidartinib) PLX5622 PLX3397 HCl PLX7904

PLX8394

PLX8394;PLX-8394;PLX 8394

1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-

(R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide

(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide

PLX8394,PLX-8394

plixorafenib

(R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide

1393466-87-9

C25H21F3N6O3S