PLX8394

ChemicalBook > CAS DataBase List > PLX8394

Product Name: PLX8394
CAS No.: 1393466-87-9
Chemical Name: PLX8394
Synonyms: PLX8394;plixorafenib;PLX8394,PLX-8394;PLX8394;PLX-8394;PLX 8394;(R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide;(R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide;1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-
CBNumber: CB83053926
Molecular Formula: C25H21F3N6O3S
Formula Weight: 542.53
MOL File: 1393466-87-9.mol

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PLX8394 Property

Density: 1.60±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : ≥ 39 mg/mL (71.89 mM);Water : < 0.1 mg/mL (insoluble)
form: Solid
pka: 6.33±0.40(Predicted)
color: White to light yellow
InChIKey: YYACLQUDUDXAPA-MRXNPFEDSA-N
SMILES: N1(S(NC2=CC=C(F)C(C(C3C4=CC(C5=CN=C(C6CC6)N=C5)=CN=C4NC=3)=O)=C2F)(=O)=O)CC[C@@H](F)C1

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Safety

HS Code: 2935909099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Biosynth Carbosynth

Product number: BP168493
Product name: PLX 8394
Packaging: 10mg
Price: $85
Updated: 2021/12/16

AK Scientific

Product number: 3017EB
Product name: (3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging: 10mg
Price: $164
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BP168493
Product name: PLX 8394
Packaging: 50mg
Price: $297.5
Updated: 2021/12/16

AK Scientific

Product number: 3017EB
Product name: (3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging: 50mg
Price: $451
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573235
Product name: PLX8394
Purity: >98%
Packaging: 100mg
Price: $1208.7
Updated: 2021/12/16

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PLX8394 Chemical Properties,Usage,Production

Uses

Combination therapies comprising KRAS G12C inhibitors and Raf kinase inhibitors for treating KRAS G12C cancers.BRAF inhibitor.

PLX8394 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PLX8394 manufacturers

Career Henan Chemical Co

Product: PLX8394 1393466-87-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-99.9%
Supply Ability: 100kg
Release date: 2019-12-26

1393466-87-9, PLX8394Related Search:

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PLX8394

PLX8394;PLX-8394;PLX 8394

1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-

(R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide

(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide

PLX8394,PLX-8394

plixorafenib

(R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide

1393466-87-9

C25H21F3N6O3S