ChemicalBook > CAS DataBase List > PLX8394

PLX8394

Product Name
PLX8394
CAS No.
1393466-87-9
Chemical Name
PLX8394
Synonyms
PLX8394;plixorafenib;PLX8394,PLX-8394;PLX8394;PLX-8394;PLX 8394;(R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide;(R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide;(3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide;1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-
CBNumber
CB83053926
Molecular Formula
C25H21F3N6O3S
Formula Weight
542.53
MOL File
1393466-87-9.mol
More
Less

PLX8394 Property

Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 39 mg/mL (71.89 mM);Water : < 0.1 mg/mL (insoluble)
form 
Solid
pka
6.33±0.40(Predicted)
color 
White to light yellow
InChIKey
YYACLQUDUDXAPA-MRXNPFEDSA-N
SMILES
N1(S(NC2=CC=C(F)C(C(C3C4=CC(C5=CN=C(C6CC6)N=C5)=CN=C4NC=3)=O)=C2F)(=O)=O)CC[C@@H](F)C1
More
Less

Safety

HS Code 
2935909099
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
BP168493
Product name
PLX 8394
Packaging
10mg
Price
$85
Updated
2021/12/16
AK Scientific
Product number
3017EB
Product name
(3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging
10mg
Price
$164
Updated
2021/12/16
Biosynth Carbosynth
Product number
BP168493
Product name
PLX 8394
Packaging
50mg
Price
$297.5
Updated
2021/12/16
AK Scientific
Product number
3017EB
Product name
(3R)-N-[3-[5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Packaging
50mg
Price
$451
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573235
Product name
PLX8394
Purity
>98%
Packaging
100mg
Price
$1208.7
Updated
2021/12/16
More
Less

PLX8394 Chemical Properties,Usage,Production

Uses

Combination therapies comprising KRAS G12C inhibitors and Raf kinase inhibitors for treating KRAS G12C cancers.BRAF inhibitor.

PLX8394 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PLX8394 Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from PLX8394 manufacturers

Career Henan Chemical Co
Product
PLX8394 1393466-87-9
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-26

1393466-87-9, PLX8394Related Search:


  • PLX8394
  • PLX8394;PLX-8394;PLX 8394
  • 1-Pyrrolidinesulfonamide, N-[3-[[5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-, (3R)-
  • (R)-N-(3-(5-(2-Cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide
  • (3R)-N-[3-[[5-(2-Cyclopropyl-5-pyrimidinyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-3-fluoro-1-pyrrolidinesulfonamide
  • PLX8394,PLX-8394
  • plixorafenib
  • (R)-N-[3-[5-(2-Cyclopropyl-5-pyrimidinyl)-7-azaindole-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
  • 1393466-87-9
  • C25H21F3N6O3S