Description Source Background

HUMAN IGFBP-4

Description Source Background
Product Name
HUMAN IGFBP-4
Chemical Name
HUMAN IGFBP-4
Synonyms
IGFBP-4;RAT IGFBP-4;HUMAN IGFBP-4;IGFBP-4 HUMAN;Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4;INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-4 HUMAN;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN IBP-4;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN HT29-IGF-BP;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN COLON CANCER CELL GROWTH INHIBITOR
CBNumber
CB5338108
Formula Weight
0
MOL File
Mol file
More
Less

HUMAN IGFBP-4 Property

storage temp. 
−20°C
form 
lyophilized powder
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Usbiological
Product number
383377
Product name
IGFBP-4
Packaging
96Tests
Price
$729
Updated
2021/12/16
Usbiological
Product number
383375
Product name
IGFBP-4
Packaging
96Tests
Price
$729
Updated
2021/12/16
More
Less

HUMAN IGFBP-4 Chemical Properties,Usage,Production

Description

IGFBP-4 Human Recombinant amino acids Asp22- Glu258, produced in HEK293 cells and fused with a polyhistidine tag at the C-terminus. IGFBP4 predicted Mw is 27kDa and on SDS-PAGE appears as a 32kDa band under denaturing conditions.
IGFBP4 is purified by proprietary chromatographic techniques.

Source

HEK293 cells

Background

Insulin-like growth factor-binding protein 4 (IGFBP-4) belongs to the insulin-like growth factor binding protein (IGFBP) family. IGFBP4 includes an IGFBP domain and a thyroglobulin type-I domain. IGFBP4 binds both insulin-like growth factors (IGFs) I and II. IGFBP-4 circulates in the plasma in both glycosylated and non-glycosylated forms. IGFBPs can either inhibit or enhance the biological activities of IGF, or act in an IGF independent manner. IGFBP-4 is exceptional since it consistently inhibits several cancer cells in vivo and in vitro, suggesting that it may function as an apoptotic factor. IGFBP4 is produced by all colon cancer cells. Binding of IGFBP-4 prolongs the half-life of the IGFs and changes their interaction with cell surface receptors.

HUMAN IGFBP-4 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

HUMAN IGFBP-4 Suppliers

China 49 Switzerland 1 United States 5 Global 55
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Cell Sciences, Inc.
Tel
--
Fax
--
Country
United States
ProdList
1065
Advantage
76
PeproTech Inc.
Tel
--
Fax
--
Email
info@peprotech.com
Country
United States
ProdList
644
Advantage
75
R & D Systems
Tel
--
Fax
--
Email
info@rndsystems.com
Country
United States
ProdList
2195
Advantage
82

HUMAN IGFBP-4Related Search:

INSULIN INSULIN INSULIN INSULIN interleukin 9 receptor IL10RA ANTI-BETA-TSH, HUMAN HE4 Interleukin-27 Activin RIIA

  • IGFBP-4 HUMAN
  • HUMAN IGFBP-4
  • HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 4
  • HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN COLON CANCER CELL GROWTH INHIBITOR
  • HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN HT29-IGF-BP
  • HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN IBP-4
  • INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-4 HUMAN
  • RAT IGFBP-4
  • IGFBP-4
  • Recombinant Human IGFBP-4/IGFBP4 Protein, His Tag