ChemicalBook > CAS DataBase List > Bendamustine

Bendamustine

Product Name
Bendamustine
CAS No.
16506-27-7
Chemical Name
Bendamustine
Synonyms
4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid;Bendamustine;4-(5-(Bis(2-chloroethyl);-1-methyl-1H-benzo[d]imidazol-2-yl);5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid;5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid;1H-BenziMidazole-2-butanoicacid, 5-[bis(2-chloroethyl)aMino]-1-Methyl-;4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;alkylating,SDX-105,inhibit,DNA Alkylator/Crosslinker,antimetabolite,purine,anticancer,Apoptosis,Bendamustine,SDX 105,Inhibitor,DNA;BendamustineQ: What is Bendamustine Q: What is the CAS Number of Bendamustine Q: What is the storage condition of Bendamustine Q: What are the applications of Bendamustine
CBNumber
CB5340488
Molecular Formula
C16H21Cl2N3O2
Formula Weight
358.26
MOL File
16506-27-7.mol
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Bendamustine Property

Boiling point:
585.2±50.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
-20°C, protect from light
solubility 
DMSO : 100 mg/mL (279.13 mM; Need ultrasonic)
pka
4.50±0.10(Predicted)
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Safety

Hazardous Substances Data
16506-27-7(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H341Suspected of causing genetic defects

H351Suspected of causing cancer

H360May damage fertility or the unborn child

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P281Use personal protective equipment as required.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P308+P313IF exposed or concerned: Get medical advice/attention.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B132558
Product name
Bendamustine
Packaging
100mg
Price
$290
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005688
Product name
BENDAMUSTINE
Purity
95.00%
Packaging
10MG
Price
$409.38
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0005688
Product name
BENDAMUSTINE
Purity
95.00%
Packaging
1G
Price
$1338
Updated
2021/12/16
Labseeker
Product number
SC-19231
Product name
Bendamustine
Purity
98
Packaging
1g
Price
$417
Updated
2021/12/16
Chemenu
Product number
CM161908
Product name
4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoicacid
Purity
95%
Packaging
1g
Price
$833
Updated
2021/12/16
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Bendamustine Chemical Properties,Usage,Production

Uses

Treatment of hematologic cancer, especially non-Hodgkin’s lymphoma.

Definition

ChEBI: Bendamustine is a member of benzimidazoles.

brand name

Ribomustine (Amcis AG, Switzerland).

Enzyme inhibitor

This nitrogen mustard and anticancer drug (FWfree-acid = 358.26 g/mol; CAS 16506-27-7), also known by its code name SDX-105, its trade names Treanda?, Treakisym?, Ribomustin?, and Levact?, as well as by its systematic name 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2- yl]butanoic acid, is a relatively nonspecific DNA alkylating agent that causes intra- and inter-strand cross-links. Bendamustine is used in the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, nonHodgkin’s lymphoma, multiple myeloma and lung cancer. Pharmacokinetics: After intravenous infusion, >95% of the drug becomes protein-bound, mainly to albumin; however, only free bendamustine is active. Bendamustine is metabolized by liver cytochrome p450, and elimination (renal) is biphasic, with an initial half-life of 6–10 minutes and a terminal half-life of approximately 30 minutes.

Bendamustine Preparation Products And Raw materials

Raw materials

Preparation Products

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Bendamustine Suppliers

China 79 Europe 1 India 11 United Kingdom 4 United States 13 USA 1 Global 109
Chengdu Saint - Kay Biotechnology Co., Ltd.
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View Lastest Price from Bendamustine manufacturers

Career Henan Chemical Co
Product
Bendamustine 16506-27-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-01-03

16506-27-7, BendamustineRelated Search:

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  • 5-(Bis(2-chloroethyl)amino)-1-methyl-2-benzimidazolebutyric acid
  • 5-[Bis(2-chloroethyl)amino]-1-methyl-1H-benzimidazole-2-butanoic acid
  • Bendamustine
  • -1-methyl-1H-benzo[d]imidazol-2-yl)
  • 4-(5-(Bis(2-chloroethyl)
  • 4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid
  • 4-(5-(bis(2-chloroethyl)aMino)-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid
  • 1H-BenziMidazole-2-butanoicacid, 5-[bis(2-chloroethyl)aMino]-1-Methyl-
  • BendamustineQ: What is Bendamustine Q: What is the CAS Number of Bendamustine Q: What is the storage condition of Bendamustine Q: What are the applications of Bendamustine
  • alkylating,SDX-105,inhibit,DNA Alkylator/Crosslinker,antimetabolite,purine,anticancer,Apoptosis,Bendamustine,SDX 105,Inhibitor,DNA
  • 16506-27-7
  • C16H21Cl2N3O2
  • C15H19Cl2N3O2