Imperatorin

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Description References

Product Name: Imperatorin
CAS No.: 482-44-0
Chemical Name: Imperatorin
Synonyms: AMMIDIN;Marmelide;MARMELOSIN;Pentosalen;NSC 402949;Imperatori;8-ISOAMYLEN;IMPERATORIN;AKOS 214-72;Enoxypsoralen
CBNumber: CB5355754
Molecular Formula: C16H14O4
Formula Weight: 270.28
MOL File: 482-44-0.mol

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Imperatorin Property

Melting point:: 98-100°C
Boiling point:: 333.4°C (rough estimate)
Density: 1.1311 (rough estimate)
refractive index: 1.4350 (estimate)
storage temp.: -20°C
solubility: DMSO: ≥5mg/mL
form: powder
color: off-white to light brown
λmax: 301nm(MeOH)(lit.)
Merck: 14,4925
InChIKey: OLOOJGVNMBJLLR-UHFFFAOYSA-N
LogP: 2.983 (est)
CAS DataBase Reference: 482-44-0(CAS DataBase Reference)
NIST Chemistry Reference: 7H-furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-butenyl)oxy]-(482-44-0)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: LV1575000
HS Code: 29419090
Hazardous Substances Data: 482-44-0(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I6659
Product name: Imperatorin
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $148
Updated: 2024/03/01

TCI Chemical

Product number: I0904
Product name: Imperatorin
Purity: >98.0%(HPLC)
Packaging: 25mg
Price: $84
Updated: 2024/03/01

TCI Chemical

Product number: I0904
Product name: Imperatorin
Purity: >98.0%(HPLC)
Packaging: 100mg
Price: $228
Updated: 2024/03/01

Cayman Chemical

Product number: 26070
Product name: Imperatorin
Purity: ≥98%
Packaging: 10mg
Price: $74
Updated: 2024/03/01

Cayman Chemical

Product number: 26070
Product name: Imperatorin
Purity: ≥98%
Packaging: 25mg
Price: $111
Updated: 2024/03/01

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Imperatorin Chemical Properties,Usage,Production

Description

Imperatorin is a kind of furocoumarin and phytochemical that present in citrus fruits. It could be isolated from Urena lobata L. (Malvaceae). It is biosynthesized from Umbelliferae in vivo. It has been found that it has anti-hypertrophic and anti-convulsant effects, and is useful in the HIV-1 research. Previous studies have shown that Imperatorin requires the transcription factor Sp1 to exert its inhibitory effect on the HIV-1. It can further inhibit the expression of cyclin D1 to cause cell cycle arrest at G1 stage. Moreover, it can suppress the HIV-1 replication inside the primary T lymphocytes and transformed cell lines. This inhibitory effect on HIV-1 can also be effectively observed in the HeLa cells. In addition, it has also been shown that it can cause apoptosis of human promyelocytic leukaemia via the cytochrome c/caspase-9 pathway.

References

https://www.scbt.com/scbt/product/imperatorin-482-44-0
https://pubchem.ncbi.nlm.nih.gov/compound/imperatorin#section=Top
https://en.wikipedia.org/wiki/Imperatorin

Chemical Properties

White Solid

Uses

Imperatorin (cas# 482-44-0) is a compound useful in organic synthesis.

Definition

ChEBI: A member of the class of psoralens that is psoralen substituted by a prenyloxy group at position 8. Isolated from Angelica dahurica and Angelica koreana, it acts as a acetylcholinesterase inhibitor.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Imperatorin is a modulator of p38, ERK pathway. Imperatorin increases BMP-2 expression (mRNA) and increases bone density/volume and mineralization in vivo.

Imperatorin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Imperatorin manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Imperatorin 482-44-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-10-12

Shanghai Standard Technology Co., Ltd.

Product: Imperatorin 482-44-0
Price: US $0.00/mg
Min. Order: 5mg
Purity: Analytical Standard
Supply Ability: 10 g
Release date: 2019-10-12

NanJing Spring & Autumn Biological Engineering CO., LTD.

Product: Imperatorin 482-44-0 482-44-0
Price: US $15.00/mg
Min. Order: 20mg
Purity: ≥98%
Supply Ability: 1000.00 kgs
Release date: 2019-07-09

482-44-0, ImperatorinRelated Search:

Ferulic Acid XANTHOTOXOL Benzofuran OXYPEUCEDANIN(RG)(PLEASE CALL) Isoimperatorin 2-(Allyloxy)phenol Psoralen 7-Methoxybenzofuran 8-Methoxypsoralen 1,2-Diethoxybenzene 2-METHOXYPHENYL ACETATE Ostruthine ALLOISOIMPERATORIN IMPERATOXIN A 1-BENZOFURAN-6-OL phellopterin 7-HYDROXYBENZOFURAN 8-METHOXYCOUMARIN

2-g)(1)benzopyran-7-one,9-((3-methyl-2-butenyl)oxy)-7h-furo(

6-hydroxy-7-((3-methyl-2-butenyl)oxy)-5-benzofuranacrylicacidelta-lacto

6-hydroxy-7-((3-methyl-2-butenyl)oxy)-5-benzofuranacrylicacidelta-lactone

6-hydroxy-7-(3-methyl-2-butenyloxy)-5-benzofuranacrylicacidomega-lactone

8-isopentenyloxypsoralene

9-((3-methyl-2-butenyl)oxy)-7h-furo(3,2-g)(1)benzopyran-7-one

9-[(3-methyl-2-butenyl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one

IMPERATORIN

8-ISOAMYLEN

8-ISOAMYLENOXYPSORALEN

AKOS 214-72

AMMIDIN

MARMELOSIN

Enoxypsoralen

Pentosalen

8-Isopentenyloxypsoralen

9-(3-Methylbut-2-enyloxy)-7H-furo[3,2-g]chromen-7-one

IMPERATORIN WITH HPLC

9-[(3-Methyl-2-butenyl)-oxy]-7H-furo[3,2-γ],[1][benzopyran-7-one

8-isopent-2-enyloxy-6,7-furanocoumarin

Marmelide

Imperatorin 482-44-0

9-(3-methylbut-2-enoxy)-7-furo[3,2-g][1]benzopyranone

AMMidin,8-Isopentenyloxypsoralen

MARMELOSIN (IMPERATORIN)

Ammidin, Marmelide, Marmelosin, NSC 402949, 9-[(3-Methyl-2-buten-1-yl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one

Imperatorin，8-Isopentenyloxypsoralen

9-(3-methylbut-2-enoxy)furo[3,2-g]chromen-7-one

MARMELOSIN (IMPERATORIN)(RG)

9-[(3-Methyl-2-buten-1-yl)oxy]-7h-furo[3,2-g][1]benzopyran-7-one

NSC 402949

Imperatorin, >=98%

Ammidin Marmelide Marmelosin NSC 402949

Baizhi Extract

Imperatorin (Ammidin)

Imperatorin CRS

Neu5Ac[1Me,4789Ac]α(2-6)Gal[24Bz,3Bn]-β-MPImperatorin

7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(3-methyl-2-buten-1-yl)oxy]-

8-(3-Methyl-2-butenyloxy)psoralen

8-Prenyloxypsoralen

9-[(3-Methyl-2-buten-1-yl)oxy]-7H-furo[3,2-g]chromen-7-one

Imperatorin USP/EP/BP

Imperatorin powder, ≥97%

Imperatorin powder, ≥98% (HPLC)

9-((3-Methylbut-2-en-1-yl)oxy)-7H-furo[3,2-g]chromen-7-one

Imperatori

Fluoroestradiol Impurity 34

Marmelosin (20 mg)

Aegle Marmelos Fruit Dry Extract (175 mg)

482-44-0

482-4-0

C16H14O4

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract