ChemicalBook > CAS DataBase List > 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate

5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate

Product Name
5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate
CAS No.
330645-87-9
Chemical Name
5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate
Synonyms
HCTU;2-(6-CHLORO-1-H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLAMINIUM HEXAFLUOROPHOSPHATE;HGTU;O-(6-ChL;HCTU 100 G;HCTU, >=99%;orobenzotriazoL;HCTU extrapure, 98%;O-(6-Chloro-1-hydroc;hexafluoro-λ-phosphanuide
CBNumber
CB5356362
Molecular Formula
C11H15ClF6N5OP
Formula Weight
413.69
MOL File
330645-87-9.mol
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5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate Property

Melting point:
185-190 °C
storage temp. 
Store at +2°C to +8°C.
solubility 
soluble in Dimethylformamide
form 
powder to crystal
color 
White to Almost white
InChIKey
ZHHGTMQHUWDEJF-UHFFFAOYSA-N
CAS DataBase Reference
330645-87-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
F 
10
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51012
Product name
HCTU
Purity
O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem?
Packaging
25g
Price
$124
Updated
2024/03/01
Sigma-Aldrich
Product number
04936
Product name
O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
Purity
≥98.0% (HPLC)
Packaging
5G-F
Price
$13.36
Updated
2024/03/01
Sigma-Aldrich
Product number
8.51012
Product name
HCTU
Purity
O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem?
Packaging
100g
Price
$369
Updated
2024/03/01
Sigma-Aldrich
Product number
04936
Product name
O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
Purity
≥98.0% (HPLC)
Packaging
25G-F
Price
$159
Updated
2024/03/01
Sigma-Aldrich
Product number
04936
Product name
O-(6-Chlorobenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium hexafluorophosphate
Purity
≥98.0% (HPLC)
Packaging
100G-F
Price
$253
Updated
2024/03/01
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5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Reagent for:
Synthesis of near-infrared pH activatable fluorescent probes
Synthesis of human β-amyloid by Fmoc chemistry
Stereoselective Horner-Wadsworth-Emmons olefination
Covalent ligation of fluorescent peptides to quantum dots
Alkylation of human telomere sequence

General Description

HCTU [1] is a novel aminium-based coupling reagent, analogous to HBTU, which in comparative studies was found to give superiort results to TBTU in the synthesis of difficult peptides [2], in hindered couplings [3], and cyclizations [4].

The product number for this product was previously 01-62-0038.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate 330645-87-9
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-26
Shanxi Naipu Import and Export Co.,Ltd
Product
HCTU 330645-87-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5000kg/month
Release date
2021-10-19
Career Henan Chemical Co
Product
5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate 330645-87-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20kg
Release date
2018-08-15

330645-87-9, 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphateRelated Search:

Lithium hexafluorophosphate Potassium hexafluorophosphate 1,2,3-1H-Triazole 5-Methyl-1H-benzotriazole Sodium hexafluorophosphate NITRIC OXIDE Methylene Blue 1H-Benzotriazole 1-CHLOROMETHYL-1H-1,2,4-TRIAZOLE ETHYLENE OXIDE 3-Dimethylaminopropylamine 4,4'-Diphenylmethane diisocyanate 1,1,3,3-Tetramethylurea (Diethoxymethyl)diphenylphosphine oxide Difluorochloromethane HBTU 6-Chloro-1-hydroxibenzotriazol 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate

  • 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate
  • 1-[BIS(DIMETHYLAMINO)METHYLEN]-5-CHLOROBENZOTRIAZOLIUM 3-OXIDE HEXAFLUOROPHOSPHATE
  • 1-[BIS(DIMETHYLAMINO)METHYLENE]-5-CHLORO-1H-BENZOTRIAZOLIUM 3-OXIDE HEXAFLUOROPHOSPHATE
  • 1-[BIS-(DIMETHYLAMINO)-METHYLENE]-5-CHLORO-1H-BENZOTRIAZOLIUM HEXAFLUOROPHOSPHATE 3-OXIDE
  • 1-(BIS-DIMETHYLAMINO-METHYLENE)-5-CHLORO-3-OXY-1H-BENZOTRIAZOL-1-IUM HEXAFLUOROPHOSPHATE
  • 2-(6-CHLORO-1-H-BENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLAMINIUM HEXAFLUOROPHOSPHATE
  • 1H-BENZOTRIAZOLIUM 1-[BIS(DIMETHYLAMINO)METHYLENE]-5CHLORO-,HEXAFLUOROPHOSPHATE (1-),3-OXIDE
  • 2-(1H-6-CHLOROBENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYL-URONIUM HEXAFLUOROPHOSPHATE
  • HCTU
  • N,N,N',N'-TETRAMETHYL-O-(6-CHLORO-1H-BENZOTRIAZOL-1-YL)URONIUM HEXAFLUOROPHOSPHATE
  • O-(1H-6-CHLOROBENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
  • O-(1H-6-CHLOROBENZOTRIAZOLE-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUORPHOSPHATE
  • O-(1H-6-CHLOROBENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
  • O-(6-CHLOROBENZOTRIAZOL-1-YL)-N,N,N',N'-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
  • O-(6-CHLORO-1-HYDROCIBENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE
  • HCTU1H-BENZOTRIAZOLIUM 1-[BIS(DIMETHYLAMINO)METHYLENE]-5CHLORO-,HEXAFLUOROPHOSPHATE (1-),3-OXIDE
  • 2-(6-Chloro-1H-benzotriazole-1-yl)-1,1,3,3-tetrame
  • o-(6-Chloro-1-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
  • HCTU O-(6-CHLORO-1-HYDROCIBENZOTRIAZOL-1-YL)- -1,1,3,3-TETRAMETHYLURONIUMHEXAFLUOROPHOSPHATE
  • 2-(1H-6-CHLOROBENZOTRIAZOL-1-YL)-N,N,N'',N''-TETRAMETHYLURONIUMHEXAFLUOROPHOSPHATE
  • O-(1H-6-CHLOROBENZOTRIAZOL-1-YL)-1,1,3,3-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE (HCTU)
  • HCTU (O-(1H-6-CHLOROBENZOTRIAZOL-1-YL)-N,N,N'',N''-TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE)
  • O-(6-Chloro-1-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+% (HPLC)
  • O-(6-Chloro-1-hydrocibenzotriazol-1-yl)-1,1,3,3-tetraMethyluroniuM hexafluorophosphat
  • O-(6-Chlorobenzotriazol-1-yl)-N,N,N
  • O-(6-Chlorobenzotriazol-1-yl)-<i>N</i>,<i>N</i>,<i>N'</i>,<i>N'</i>-tetramethyluronium hexafluorophosphate
  • 1H-BenzotriazoliuM,1-[bis(diMethylaMino)Methylene]-5-chloro-, 3-oxide, hexafluorophosphate(1-)(1:1)
  • HCTU, >=99%
  • [(6-chlorobenzotriazol-1-yl)oxy-(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate
  • O-(1H-6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate≥ 98% (HPLC)
  • O-(1H-6-Chlorobenzotriazol-1-yl)-1,1,3,3- tetramethyluronium hexafluorophosphate for synthesis
  • HCTU O-(1H-6-Chlorobenzotriazole-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate Novabiochem
  • 1-[bis(dimethylamino)methylidene]-5-chloro-3-oxo-1H-1λ,2,3λ-benzotriazol-1-ylium
  • hexafluoro-λ-phosphanuide
  • O(6Chlo1hydrocibenzotriazol1yl)1133tetramethyluronium hexafluophosphat
  • 1-[BIS(DIMETHYLAMINO)METHYLENE]-5-CHLORO-1H-BENZOTRIAZOLIUM 3-OXIDE HEXAFLUOROPHOSPH
  • [(6-chloro-1-benzotriazolyl)oxy-(dimethylamino)methylidene]-dimethylammonium hexafluorophosphate
  • O-(6-Chloro-1-hydrocibenzotriazol-1-yl)- -1,1,3,3-tetramethyluroniumhexafluorophosphate(HCTU)
  • 1-[Bis(dimethylamino)methylene]-5-chloro-1H-benzotriazolium 3-oxide hexafluorophosphate(1-) (1:1)
  • [(6-chlorobenzotriazol-1-yl)oxy-(dimethylamino)methylene]-dimethyl-ammonium
  • O-(1H-6-Chlorobenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexa
  • HCTU, 1-[Bis(dimethylamino)methylen]-5-chlorobenzotriazolium 3-oxide hexafluorophosphate, N,N,Nμ,Nμ-Tetramethyl-O-(6-chloro-1H-benzotriazol-1-yl)uronium hexafluorophosphate
  • O-(1H-6-Chlorobenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate ,98%
  • O-(6-Chloro-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+% (HPLC)
  • O-(6-Chloro-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate
  • O-(6-Chloro-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98+%
  • O-(6-Chloro-1-hydroc
  • HCTU 5-Chloro-1-[bis(diMethylaMino)Methylene]-1H-benzotriazoliuM 3-oxide hexafluorophosphate
  • O-(1H-6-CHLOROBENZOTRIAZOL--1-YL)-1,1,3
  • 2-(6-Chloro-1H-benzo[d][1,2,3]triazol-1-yl)-1,1,3,3-tetraMethyluroniuM hexafluorophosphate(V)
  • HGTU
  • 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium
  • O-(6-Chlorobenzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate &gt
  • HCTU 100 G
  • O-(6-ChL
  • orobenzotriazoL
  • 5-Chloro-1-[bis(dimethylamino)methylene]-1H-benzotriazolium 3-oxide hexafluorophosphate USP/EP/BP
  • 2-[(2,5-dioxopyrrolidin-1-yl)oxy]-1,3,4-trimethyl-4,5-dihydro-1H-imidazol-3-ium