ChemicalBook > CAS DataBase List > TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER

TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER

Product Name
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER
CAS No.
15177-67-0
Chemical Name
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER
Synonyms
TRANS-4-(METHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID;trans-4-(Methoxycarbonyl);Monmethyl trans-1,4-cyclohexanedicarboxylate;MonoMethyl trans-1,4-cyclohexanedicarboxylate;Methyl trans-4-carboxycyclohexane-1-carboxylate;4(METHOXY CARBONYL) CYCLOHEXANE CARBOXYLIC ACID;4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER;TRANS-4-CARBOMETHOXYCYCLOHEXANE-1-CARBOXYLIC ACID;TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL;Monomethyl trans-1,4-Cyclohexanedicarboxylate >
CBNumber
CB5363218
Molecular Formula
C9H14O4
Formula Weight
186.21
MOL File
15177-67-0.mol
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TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER Property

Melting point:
126.0 to 130.0 °C
Boiling point:
303.1±35.0 °C(Predicted)
Density 
1.191±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
powder to crystal
pka
4.66±0.10(Predicted)
color 
White to Almost white
InChI
InChI=1S/C9H14O4/c1-13-9(12)7-4-2-6(3-5-7)8(10)11/h6-7H,2-5H2,1H3,(H,10,11)/t6-,7-
InChIKey
ZQJNPHCQABYENK-LJGSYFOKSA-N
SMILES
[C@@H]1(C(OC)=O)CC[C@@H](C(O)=O)CC1
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Safety

Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
HazardClass 
IRRITANT
HS Code 
2917200090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

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N-Bromosuccinimide Price

TCI Chemical
Product number
M2526
Product name
Monomethyl trans-1,4-Cyclohexanedicarboxylate
Purity
>97.0%(GC)(T)
Packaging
5g
Price
$52
Updated
2025/07/31
TCI Chemical
Product number
M2526
Product name
Monomethyl trans-1,4-Cyclohexanedicarboxylate
Purity
>97.0%(GC)(T)
Packaging
25g
Price
$175
Updated
2025/07/31
TRC
Product number
C997758
Product name
trans-1,4-CyclohexanedicarboxylicAcidMonomethylEster
Packaging
100mg
Price
$45
Updated
2021/12/16
Usbiological
Product number
290693
Product name
Trans-1,4-cyclohexane dicarboxylic acid monomethyl ester
Packaging
5g
Price
$342
Updated
2021/12/16
Oakwood
Product number
047211
Product name
trans-1,4-Cyclohexanedicarboxylicacidmonomethylester
Purity
98%
Packaging
1g
Price
$10
Updated
2021/12/16
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TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER Chemical Properties,Usage,Production

Uses

Trans-cyclohexane-1,4-dicarboxylic acid monomethyl ester is a carboxylic acid ester derivative, used as organic reagents.

Synthesis

94-60-0

15177-67-0

(1) Isomerization reaction: 0.5 mol (100.1 g) of dimethyl 1,4-cyclohexanedicarboxylate (Ib) with a trans/cis isomer ratio of 3/7 to 5/5 was dissolved in 200 g of methanol at 40°C. The reaction was carried out by adding 15 g of pyridine as a catalyst. 15 g of pyridine was added as a catalyst, and after 2 h of reaction, a methanolic solution of dimethyl 1,4-cyclohexanedicarboxylate (II-b) with a trans/cis isomer ratio of 9/1 was obtained. (2) Monoester hydrolysis reaction: The methanol solution of dimethyl 1,4-cyclohexanedicarboxylate (II-b) with a trans/cis isomer ratio of 9/1 obtained in step (1) was cooled to room temperature, and 150 g of potassium hydroxide was added. The reaction was carried out at 20°C for 3 h. Monoester hydrolysis was carried out to obtain a water-soluble carboxylic acid ester of trans-1,4-cyclohexanedicarboxylic acid monomethyl ester. (3) Acidification and post-treatment: 200 g of water and 100 g of toluene were added to the reaction system of step (2), and the organic phase was removed by extraction and stratification. The aqueous phase was adjusted to pH 1-2 with concentrated hydrochloric acid and the mixture was cooled to 0 °C. After filtration, the mixture was dried under reduced pressure at 50 °C to afford 66.4 g of white solid powder of monomethyl trans-1,4-cyclohexanedicarboxylate (III). The yield was 71.32% and the purity of compound (III) was 98.9% as determined by gas chromatography.

References

[1] Patent: CN108129307, 2018, A. Location in patent: Paragraph 0027-0041

TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER Suppliers

Shanghai Targsense Scientific Co., Ltd.
Tel
18916626092
Email
targsense@qq.com
Country
China
ProdList
110
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65
Chongqing Acemol Technology Co.,Ltd
Tel
023-86822659 18611316925
Email
sales@acemol.com
Country
China
ProdList
993
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55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
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China
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96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
Fax
86-21-61259102
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market03@meryer.com
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China
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40228
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INTATRADE GmbH
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+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
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Germany
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ChemFuture PharmaTech (Jiangsu) Ltd
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5108538618
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86 510 85386988-8017
Email
suger.wang@chemfuture.com
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China
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832
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
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2355560935@qq.com
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China
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12000
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
Fax
0573-85285100
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isenchem@163.com
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China
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View Lastest Price from TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER 15177-67-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-28
Shaanxi Dideu New Materials Co. Ltd
Product
TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER 15177-67-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-02-26
Honest Joy Holdings Limited
Product
Trans-1,4-cyclohexanedicarboxylic acid monomethyl ester 15177-67-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
100 tons
Release date
2022-02-08

15177-67-0, TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTERRelated Search:


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  • TRANS-4-CARBOMETHOXYCYCLOHEXANE-1-CARBOXYLIC ACID
  • 4(METHOXY CARBONYL) CYCLOHEXANE CARBOXYLIC ACID
  • TRANS-4-(METHOXYCARBONYL)CYCLOHEXANECARBOXYLIC ACID
  • (1r,4r)-4-(methoxycarbonyl)cyclohexanecarboxylic acid
  • Methyl trans-4-carboxycyclohexane-1-carboxylate
  • trans-4-(Methoxycarbonyl)cyclohexane-1-carboxylic acid
  • TRANS-1,4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL
  • Trans-1,4-cyclohexane dicarboxalic acid MonoMethyl ester
  • Methyl trans-4-carboxycyclohexane-1-carboxylate, trans-1-Carboxy-4-(methoxycarbonyl)cyclohexane
  • MonoMethyl trans-1,4-cyclohexanedicarboxylate
  • 1,4-Cyclohexanedicarboxylic acid, MonoMethyl ester, trans-
  • trans-cyclohexane-1,4-dicarboxylic acid MonoMethyl ester
  • Monmethyl trans-1,4-cyclohexanedicarboxylate
  • 1,4-Cyclohexanedicarboxylic acid, 1-Methyl ester, trans-
  • trans-1,4-Cyclohexanedicarboxylic Acid MonoMethyl Ester, 97+%
  • Trans-1,4-cyclohexanedicarboxylic caid MonoMethyl ester
  • (1r,4r)-4-(methoxycarbonyl)cyclohexane-1-carboxylicacid
  • Monomethyl <i>trans</i>-1,4-Cyclohexanedicarboxylate
  • trans-4-(Methoxycarbonyl)
  • trans-1,4-cyclohexanecarboxylic acid monomethyl ester
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  • 4-CYCLOHEXANEDICARBOXYLIC ACID MONOMETHYL ESTER
  • ItemName-(1r,4r)-4-(methoxycarbonyl)cyclohexanecarboxylicacid
  • 15177-67-0
  • API