27-DEOXYACTEIN

Product Name: 27-DEOXYACTEIN
CAS No.: 264624-38-6
Chemical Name: 27-DEOXYACTEIN
Synonyms: Deoxycosimatin;27-DEOXYACTEIN;26-DEOXYACTEIN;DEOXYACTEIN, 27-;23-EPI-26-DEOXYACTEIN;23-EPI-26-Deoxyactein (20 mg);DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P);Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein;β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl;(3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside
CBNumber: CB5365803
Molecular Formula: C37H56O10
Formula Weight: 660.83
MOL File: 264624-38-6.mol

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27-DEOXYACTEIN Property

Melting point:: 253～254℃
Density: 1.32±0.1 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Very Slightly), Pyridine (Slightly)
form: Solid
pka: 13.03±0.70(Predicted)
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25126
Product name: 23-epi-26-Deoxyactein
Purity: ≥95%
Packaging: 500μg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 25126
Product name: 23-epi-26-Deoxyactein
Purity: ≥95%
Packaging: 1mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 25126
Product name: 23-epi-26-Deoxyactein
Purity: ≥95%
Packaging: 5mg
Price: $231
Updated: 2024/03/01

TRC

Product number: D231635
Product name: 27-Deoxyactein
Packaging: 1mg
Price: $305
Updated: 2021/12/16

ChemScene

Product number: CS-0032801
Product name: 27-Deoxyactein
Packaging: 5mg
Price: $403
Updated: 2021/12/16

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27-DEOXYACTEIN Chemical Properties,Usage,Production

Description

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.

Uses

27-Deoxyactein has shown stimulation of osteoblast function and inhibits bone resorbing mediators in the treatment of osteoporosis. It is a derivative of Actein (A191800), a gamma secretase modulators derived from botanicals.

Definition

ChEBI: 26-Deoxyactein is a triterpenoid. It has a role as a metabolite.

27-DEOXYACTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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27-DEOXYACTEIN Suppliers

China 61 France 1 Germany 3 United Kingdom 3 United States 7 Global 75

J & K SCIENTIFIC LTD.

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264624-38-6, 27-DEOXYACTEINRelated Search:

CIMICIFUGOSIDE M CIMICIFUGOSIDE 3,4-Epoxytetrahydrofuran TRIDECYL GLYCIDYL ETHER 27-DEOXYACTEIN CYCLOARTANOL 1,2-EPOXYEICOSANE ISONOMETAL 3993 P LAURYL GLYCIDYL ETHER CYCLOARTANE GLYCIDYL HEXADECYL ETHER (R)-(+)-2,3-EPOXYPROPYL HEXYL ETHER (R)-(+)-GLYCIDYL UNDECYL ETHER, 97 Actein DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(AHP) 2'-O-acetyl-27-deoxyactein TRANS,TRANS-4''-PENTYL-4-ETHOXY-BICYCLOHEXYL 2-[(cyclopentyloxy)methyl]oxirane

23-EPI-26-Deoxyactein (20 mg)

DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P)

(3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside

DEOXYACTEIN, 27-

23-EPI-26-DEOXYACTEIN

26-DEOXYACTEIN

27-DEOXYACTEIN

β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl

Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein

Deoxycosimatin

264624-38-6