27-DEOXYACTEIN
- Product Name
- 27-DEOXYACTEIN
- CAS No.
- 264624-38-6
- Chemical Name
- 27-DEOXYACTEIN
- Synonyms
- Deoxycosimatin;27-DEOXYACTEIN;26-DEOXYACTEIN;DEOXYACTEIN, 27-;23-EPI-26-DEOXYACTEIN;23-EPI-26-Deoxyactein (20 mg);DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P);Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein;β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl;(3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside
- CBNumber
- CB5365803
- Molecular Formula
- C37H56O10
- Formula Weight
- 660.83
- MOL File
- 264624-38-6.mol
27-DEOXYACTEIN Property
- Melting point:
- 253～254℃
- Density
- 1.32±0.1 g/cm3(Predicted)
- storage temp.
- Hygroscopic, -20°C Freezer, Under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Very Slightly), Pyridine (Slightly)
- form
- Solid
- pka
- 13.03±0.70(Predicted)
- color
- White to Off-White
- Stability:
- Hygroscopic
N-Bromosuccinimide Price
- Product number
- 25126
- Product name
- 23-epi-26-Deoxyactein
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 25126
- Product name
- 23-epi-26-Deoxyactein
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 25126
- Product name
- 23-epi-26-Deoxyactein
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $231
- Updated
- 2024/03/01
- Product number
- D231635
- Product name
- 27-Deoxyactein
- Packaging
- 1mg
- Price
- $305
- Updated
- 2021/12/16
- Product number
- CS-0032801
- Product name
- 27-Deoxyactein
- Packaging
- 5mg
- Price
- $403
- Updated
- 2021/12/16
27-DEOXYACTEIN Chemical Properties,Usage,Production
Description
23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.
Uses
27-Deoxyactein has shown stimulation of osteoblast function and inhibits bone resorbing mediators in the treatment of osteoporosis. It is a derivative of Actein (A191800), a gamma secretase modulators derived from botanicals.
Definition
ChEBI: 26-Deoxyactein is a triterpenoid. It has a role as a metabolite.
27-DEOXYACTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
27-DEOXYACTEIN Suppliers
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- Country
- Germany
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