ChemicalBook > CAS DataBase List > 27-DEOXYACTEIN

27-DEOXYACTEIN

Product Name
27-DEOXYACTEIN
CAS No.
264624-38-6
Chemical Name
27-DEOXYACTEIN
Synonyms
Deoxycosimatin;27-DEOXYACTEIN;26-DEOXYACTEIN;DEOXYACTEIN, 27-;23-EPI-26-DEOXYACTEIN;23-EPI-26-Deoxyactein (20 mg);DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P);Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein;β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl;(3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside
CBNumber
CB5365803
Molecular Formula
C37H56O10
Formula Weight
660.83
MOL File
264624-38-6.mol
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27-DEOXYACTEIN Property

Melting point:
253～254℃
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), Methanol (Very Slightly), Pyridine (Slightly)
form 
Solid
pka
13.03±0.70(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
25126
Product name
23-epi-26-Deoxyactein
Purity
≥95%
Packaging
500μg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
25126
Product name
23-epi-26-Deoxyactein
Purity
≥95%
Packaging
1mg
Price
$68
Updated
2024/03/01
Cayman Chemical
Product number
25126
Product name
23-epi-26-Deoxyactein
Purity
≥95%
Packaging
5mg
Price
$231
Updated
2024/03/01
TRC
Product number
D231635
Product name
27-Deoxyactein
Packaging
1mg
Price
$305
Updated
2021/12/16
ChemScene
Product number
CS-0032801
Product name
27-Deoxyactein
Packaging
5mg
Price
$403
Updated
2021/12/16
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27-DEOXYACTEIN Chemical Properties,Usage,Production

Description

23-epi-26-Deoxyactein is a triterpene glycoside and a major constituent of black cohosh (C. racemosa). It reduces intracellular calcium concentrations, collapse of the mitochondrial membrane potential, production of reactive oxygen species (ROS), and cardiolipin peroxidation and inhibits autophagy and apoptosis in osteoblastic MC3T3-E1 cells induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). 23-epi-26-Deoxyactein (0.01-10 μM) reduces production of ROS and IL-1β and cell death induced by methylglyoxal in RIN-m5F β-cells.

Uses

27-Deoxyactein has shown stimulation of osteoblast function and inhibits bone resorbing mediators in the treatment of osteoporosis. It is a derivative of Actein (A191800), a gamma secretase modulators derived from botanicals.

Definition

ChEBI: 26-Deoxyactein is a triterpenoid. It has a role as a metabolite.

27-DEOXYACTEIN Preparation Products And Raw materials

Raw materials

Preparation Products

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27-DEOXYACTEIN Suppliers

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264624-38-6, 27-DEOXYACTEINRelated Search:

CIMICIFUGOSIDE M CIMICIFUGOSIDE 3,4-Epoxytetrahydrofuran TRIDECYL GLYCIDYL ETHER 27-DEOXYACTEIN CYCLOARTANOL 1,2-EPOXYEICOSANE ISONOMETAL 3993 P LAURYL GLYCIDYL ETHER CYCLOARTANE GLYCIDYL HEXADECYL ETHER (R)-(+)-2,3-EPOXYPROPYL HEXYL ETHER (R)-(+)-GLYCIDYL UNDECYL ETHER, 97 Actein DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(AHP) 2'-O-acetyl-27-deoxyactein TRANS,TRANS-4''-PENTYL-4-ETHOXY-BICYCLOHEXYL 2-[(cyclopentyloxy)methyl]oxirane

  • 23-EPI-26-Deoxyactein (20 mg)
  • DEOXYACTEIN, 27-(23-EPI-26-DEOXYACTEIN)(P)
  • (3beta,12beta,16beta,23S,24R,25R)-12-(Acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl beta-D-xylopyranoside
  • DEOXYACTEIN, 27-
  • 23-EPI-26-DEOXYACTEIN
  • 26-DEOXYACTEIN
  • 27-DEOXYACTEIN
  • β-D-Xylopyranoside, (3β,12β,16β,23S,24R,25R)-12-(acetyloxy)-16,23:23,26:24,25-triepoxy-9,19-cyclolanostan-3-yl
  • Inhibitor,26Deoxyactein,26-Deoxyactein,inhibit,26 Deoxyactein
  • Deoxycosimatin
  • 264624-38-6