ChemicalBook > CAS DataBase List > 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE

15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE

Product Name: 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE
CAS No.: 2623-22-5
Chemical Name: 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE
Synonyms: 15-mas;NSC-267030;deacetylanguidin;Desacetylanguidine;15-ACETOXYSCIRPENOL;monoacetoxyscirpenol;15-ACETOXYSCIRPENDIOL;Acetoxyscirpenol, 15-;15-MONOACETYLSCIRPENOL;15-MONOACETOXYSCIRPENOL
CBNumber: CB5379697
Molecular Formula: C17H24O6
Formula Weight: 324.37
MOL File: 2623-22-5.mol

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15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE Property

Melting point:: 170-172 °C
Boiling point:: 465.5±45.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: ≤10mg/ml in methanol;10mg/ml in dichloromethane
form: powder
pka: 13.72±0.70(Predicted)
color: White to off-white

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: YD0111000
HazardClass: 6.1(a)
PackingGroup: II
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 11431
Product name: 15-acetoxy Scirpenol
Purity: ≥98%
Packaging: 1mg
Price: $242
Updated: 2024/03/01

Cayman Chemical

Product number: 11431
Product name: 15-acetoxy Scirpenol
Purity: ≥98%
Packaging: 5mg
Price: $965
Updated: 2024/03/01

Usbiological

Product number: 412029
Product name: 15-Acetoxyscirpenol
Packaging: 1mg
Price: $885
Updated: 2021/12/16

TRC

Product number: A164293
Product name: 15-Acetoxyscirpenol
Packaging: 10mg
Price: $4070
Updated: 2021/12/16

ApexBio Technology

Product number: C4698
Product name: 15-acetoxyScirpenol
Packaging: 5mg
Price: $1104
Updated: 2021/12/16

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15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

15-Acetoxyscirpenol is a trichothecene mycotoxin and an apoptosis inducer.

Hazard

A poison by ingestion. A mild skin irritant.

Biological Activity

15-acetoxy scirpenol is a trichothecene mycotoxin which is produced predominantly by members of the fusarium genus [1]. 15-acetoxy scirpenol could induce apoptotic cell death in human jurkat t cells. mycotoxins of scirpenol belong to the trichothecene family which is mainly produced by the fungal species of the genus fusarium. acetoxylated scirpenol has very high toxicities in animals and humans. 15-acetoxy scirpenol exhibited cytotoxicity at a lower concentration (25 ng/ml). the 50% inhibitory concentration (ic50) values of 15-acetoxy scirpenol was 16.1 ng/ml [2]. in the jurkat t cells treated with 50 ng/ml of 15-acetoxyscirpenol (15-mas), the populations of externalized ps-positive and pi-negative cells were 32.0% [2].

IC 50

Caspase

References

[1] peraica m, radic b, lucic a, et al. toxic effects of mycotoxins in humans[j]. bulletin of the world health organization, 1999, 77(9): 754-766.
[2] lee d h, park t, kim h w. induction of apoptosis by disturbing mitochondrial-membrane potential and cleaving parp in jurkat t cells through treatment with acetoxyscirpenol mycotoxins[j]. biological and pharmaceutical bulletin, 2006, 29(4): 648-654.

15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE Preparation Products And Raw materials

Raw materials

Preparation Products

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15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE Suppliers

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2623-22-5, 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENERelated Search:

ENOLASE Octyl 4-methoxycinnamate 1,3-cyclopentanediol (TETRAHYDRO-2H-PYRAN-4-YL)METHANOL 3-METHOXYCYCLOHEXENE 15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) Ethylhexylglycerin 1,1-DIETHYLCYCLOPROPANE (TETRAHYDRO-PYRAN-3-YL)-METHANOL 1-METHYL-3-CYCLOHEXENE-1-METHANOL 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL 3-METHYL-2-CYCLOHEXEN-1-OL 2-TERT-BUTYLPROPANE-1,3-DIOL 1-CYCLOPROPYLETHANOL (S)-1-CYCLOPROPYLETHANOL

deacetylanguidin

monoacetoxyscirpenol

15-ACETOXY-3ALPHA,4BETA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-ENE

15-ACETOXYSCIRPENDIOL

15-ACETOXYSCIRPENOL

(3-alpha)-12,13-epoxytrichothec-9-ene-3,4,15-triol15-acetate

15-mas

4-beta,15-triol,12,13-epoxy-trichothec-9-ene-3-alph15-acetate

((2R,2S,3R,5R,5AR,9aR)-3-hydroxy-5,8-dimethyl-2,3,4,5,5a,6,7,9a-octahydrospiro[2,5-methanobenzo[b]oxepine-10,2-oxiran]-5a-yl)methyl acetate

15-acetoxy-3α,4β-dihydroxy-12,13-epoxytrichothec-9-ene

15-MONOACETYLSCIRPENOL

15-MONOACETOXYSCIRPENOL

15-Acetoxyscirpendiol, 15-Acetoxy-3α,4β-dihydroxy-12,13-epoxytrichothec-9-ene

12,13-Epoxytrichothec-9-ene-3α,4β,15-triol 15-acetate

3α,4β-Dihydroxy-15-acetoxy-12,13-epoxytrichotheca-9-ene

NSC-267030

Anguidine, desacetyl(15-acetoxyscirpene-3,4-diol-bl5732)

Desacetylanguidine

Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 15-acetate, (3.alpha.,4.beta.)-

Trichothec-9-ene-3.alpha.,4.beta.,15-triol, 12,13-epoxy-, 15-acetate

15 Acetoxyscirpenol (3alpha,4beta)-12,13-epoxy-trichothec-9-ene-3,4,15-triol 15-acetate

Trichothec-9-ene-3,4,15-triol, 12,13-epoxy-, 15-acetate, (3α,4β)-

Trichothec-9-ene-3.α.,4.β.,15-triol, 12,13-epoxy-, 15-acetate

((2S,2'R,3'R,5'R,5a'R,9a'R)-3'-Hydroxy-5',8'-dimethyl-2',3',4',5',7',9a'-hexahydrospiro[oxirane-2,10'-[2,5]methanobenzo[b]oxepin]-5a'(6'H)-yl)methyl acetate

15-Acetoxyscirpenol in acetonitrile

Acetoxyscirpenol-15 in Acetonitrile

Acetoxyscirpenol, 15-

15-Acetyl diacetoxyscirpenol

2623-22-5