2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL

Product Name: 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL
CAS No.: 4677-18-3
Chemical Name: 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL
Synonyms: 2-(tetrahydro-2H-pyran-4-yl)ethan-1-ol;2-(oxan-4-yl)ethanol;2-(oxan-4-yl)ethan-1-ol;Tetrahydro-pyran-4-ethanol;Tetrahydro-2H-pyran-4-ethanol;(4-HYDROXYETHYL)TETRAHYDROPYRAN;2H-Pyran-4-ethanol, tetrahydro-;4-(2-Hydroxyethyl)tetrahydropyran;2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL;2-TETRAHYDRO-2H-PYRAN-4-YLETHANOL
CBNumber: CB5182734
Molecular Formula: C7H14O2
Formula Weight: 130.18
MOL File: 4677-18-3.mol

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2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL Property

Boiling point:: 226℃
Density: 0.981
Flash point:: 95℃
storage temp.: 2-8°C
pka: 15.06±0.10(Predicted)
Appearance: Colorless to light yellow Liquid

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Safety

Hazard Codes: Xi
Risk Statements: 10-21/22-36/37/38-41-37/38
Safety Statements: 16-23-26-36/37/39-39
RIDADR: UN1987
HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: E588803
Product name: 2-(Oxan-4-yl)ethan-1-ol
Packaging: 500mg
Price: $130
Updated: 2021/12/16

SynQuest Laboratories

Product number: 2H10-1-Y5
Product name: 4-(2-Hydroxyethyl)tetrahydro-2H-pyran
Packaging: 1g
Price: $136
Updated: 2021/12/16

Ark Pharm

Product number: P000046209
Product name: 2-(Tetrahydro-2H-pyran-4-yl)ethanol
Purity: 98%
Packaging: 1g
Price: $76
Updated: 2021/12/16

Ark Pharm

Product number: P000046209
Product name: 2-(Tetrahydro-2H-pyran-4-yl)ethanol
Purity: 98%
Packaging: 5g
Price: $248
Updated: 2021/12/16

Matrix Scientific

Product number: 084243
Product name: 2-Tetrahydro-2H-pyran-4-ylethanol
Purity: 97%
Packaging: 1g
Price: $396
Updated: 2021/12/16

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2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL Chemical Properties,Usage,Production

Uses

2-(Tetrahydropyran-4-yl)-ethanol is mainly used as an intermediate in organic synthesis, especially in the field of pharmaceutical manufacturing.

Synthesis

103260-44-2

4677-18-3

General procedure for the synthesis of tetrahydropyran-4-ethanol from ethyl tetrahydropyran-4-yl-acetate: To a stirred suspension of lithium aluminium hydride (5.10 g, 138 mmol) in tetrahydrofuran (200 mL) at 0 °C, a tetrahydrofuran (50 mL) solution of ethyl 2-(tetrahydropyran-4-yl)acetate (22.0 g, 138 mmol) was slowly added dropwise. After the dropwise addition was completed, the reaction mixture was heated to reflux overnight. Upon completion of the reaction, the mixture was cooled in an ice bath, followed by the addition of ether (300 mL) and dropwise addition of 5N sodium hydroxide solution until a large white precipitate was formed. The suspension was filtered, the filtrate was dried with anhydrous potassium carbonate, filtered again and concentrated by rotary evaporation to give tetrahydropyran-4-ethanol (17.7 g, 100% yield) as a colorless liquid.

References

[1] Journal of Organic Chemistry, 2006, vol. 71, # 26, p. 9909 - 9911
[2] Patent: US2004/220214, 2004, A1
[3] Patent: WO2013/37960, 2013, A1. Location in patent: Page/Page column 76
[4] Patent: US9481674, 2016, B1. Location in patent: Page/Page column 31; 32
[5] Bioorganic and Medicinal Chemistry, 2005, vol. 13, # 23, p. 6309 - 6323

2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL Preparation Products And Raw materials

Raw materials

TRIETHYL PHOSPHONOACETATE Sodium hydride Tetrahydro-4H-pyran-4-one Palladium Tetrahydrofuran Lithium Aluminum Hydride

Preparation Products

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2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL Suppliers

Austria 1 Belgium 1 China 98 India 2 United Kingdom 2 United States 13 Global 117

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
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Yangzhou Siyu Chemical Co.,Ltd.

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Beijing Ouhe Technology Co., Ltd

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Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
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Shanghai Paulshine Chemical Co., Ltd.

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Country: China
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Wuxi InterpiPharm, Inc.

Tel: 510-83782303 13771177691
Fax: 0510- 8378-9906
Email: sales@itppharm.com
Country: China
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Thermo Fisher Scientific

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9ding chemical ( Shanghai) Limited

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SynAsst Chemical.

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AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: 15928766785 15928766785
Fax: QQ961458712
Email: wupengcheng@astatech.cn
Country: China
ProdList: 1987
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Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
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View Lastest Price from 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL manufacturers

Dideu Industries Group Limited

Product: 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL 4677-18-3
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-29

Career Henan Chemical Co

Product: 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL 4677-18-3
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-24

4677-18-3, 2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOLRelated Search:

Tetrahydropyran-4-carbaldehyde 4-Amidinotetrahydro-2H-pyran hydrochloride Tetrahydropyran-4-boronic acid pinacol ester Tetrahydro-4-pyranol Tetrahydropyranyl-4-acetic acid Methyl tetrahydropyran-4-carboxylate Tetrahydro-4H-pyran-4-one Tetrahydro-2H-pyran-4-carboxylic acid TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Tetrahydro-pyran-4-yl)-hydrazine TETRAHYDRO-PYRAN-3-CARBALDEHYDE Ethyl Tetrahydropyran-4-Carboxylate 4-(Dimethylamino)tetrahydro-2H-pyran TETRAHYDRO-2H-PYRAN-3-CARBOXYLIC ACID 4-Aminotetrahydro-2H-pyran acetate [(Tetrahydro-2H-pyran-4-yl)methyl]hydrazine dihydrochloride ETHYL TETRAHYDROPYRAN-4-YL-ACETATE TETRAHYDROFURAN-3-CARBOXALDEHYDE 98

(4-HYDROXYETHYL)TETRAHYDROPYRAN

4-(2-Hydroxyethyl)tetrahydro-2H-pyran

2-TETRAHYDRO-2H-PYRAN-4-YLETHANOL

2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL

4-(2-Hydroxyethyl)tetrahydro-2H-pyran 97%

4-(2-Hydroxyethyl)tetrahydropyran

Tetrahydro-2H-pyran-4-ethanol

Tetrahydro-pyran-4-ethanol

2-(Tetrahydro-2H-pyran-4-yl)ethan-1-ol, 4-(2-Hydroxyethyl)oxane

2-(oxan-4-yl)ethan-1-ol

2-(oxan-4-yl)ethanol

2-(TETRAHYDRO-2H-PYRAN-4-YL)ETHANOL(WXC08518)

2H-Pyran-4-ethanol, tetrahydro-

2-(tetrahydro-2H-pyran-4-yl)ethan-1-ol

2-(TETRAHYDRO-PYRAN-4-YL)-ETHANOL ISO 9001：2015 REACH

2-(Tetrahydro-2H-pyran-4-yl)ethanol , (4-hydroxyethyl)tetrahydropyran

4677-18-3

Pyrans, Piperidines & Piperazines

Hydroxymethyl's

Pyrans, Piperidines &Piperazines