TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
- Product Name
- TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
- CAS No.
- 344329-76-6
- Chemical Name
- TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE
- Synonyms
- oxane-4-carboxamide;4-CARBAMOYLTETRAHYDROPYRAN;4-tetrahydropyrancarboxamide;Tetrahydropyran-4-carboxamid;1-benzothiophen-7-ylmethanol;tetrahydropyran-4-carboxamide;4-Carbamoyltetrahydro-2H-pyran;4-Carbamoyltetrahydropyran, 98%;TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE;2H-Pyran-4-carboxamide, tetrahydro-
- CBNumber
- CB5311628
- Molecular Formula
- C6H11NO2
- Formula Weight
- 129.16
- MOL File
- 344329-76-6.mol
TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Property
- Melting point:
- 181-183
- Boiling point:
- 312.1±31.0 °C(Predicted)
- Density
- 1.114
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 16.31±0.20(Predicted)
- form
- solid
- color
- White
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 22-20/21/22
- Safety Statements
- 24/25-36/37
- Hazard Note
- Irritant/Keep Cold
- HazardClass
- IRRITANT
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- C175908
- Product name
- 4-Carbamoyltetrahydropyran
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR9367
- Product name
- Tetrahydro-2H-pyran-4-carboxamide
- Purity
- 98%
- Packaging
- 5g
- Price
- $32
- Updated
- 2021/12/16
- Product number
- T13185
- Product name
- Tetrahydro-2H-pyran-4-carboxamide
- Purity
- 98%
- Packaging
- 5g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- T13185
- Product name
- Tetrahydro-2H-pyran-4-carboxamide
- Purity
- 98%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- OR9367
- Product name
- Tetrahydro-2H-pyran-4-carboxamide
- Purity
- 98%
- Packaging
- 1g
- Price
- $13
- Updated
- 2021/12/16
TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
110238-91-0
344329-76-6
The general procedure for the synthesis of tetrahydropyran-4-carboxamide from methyl tetrahydropyran-4-carboxylate was as follows: tetrahydro-2H-pyran-4-carboxylic acid methyl ester (7 g, 48.6 mmol) was mixed with 30% ammonia (20 mL) in a closed reaction flask, and the reaction was stirred at room temperature for 18 hours. Upon completion of the reaction, the excess ammonia was removed by distillation under reduced pressure and the residue was recrystallized from ethanol to give 5.6 g (89% yield) of the target product, tetrahydro-2H-pyran-4-carboxamide. The structure of the product was confirmed by 1H NMR (401 MHz, DMSO-d6) with chemical shifts δ ppm of 7.21 (br.s, 1H), 6.73 (br.s, 1H), 3.90-3.80 (m, 2H), 3.30-3.23 (m, 2H), 2.36-2.24 (m, 1H), 1.66-1.47 (m, 4H ).
References
[1] Patent: WO2012/113774, 2012, A1. Location in patent: Page/Page column 41-42
[2] Patent: US2013/324551, 2013, A1. Location in patent: Paragraph 0326; 0327
[3] ChemMedChem, 2015, vol. 10, # 2, p. 276 - 295
[4] Patent: WO2015/62486, 2015, A1. Location in patent: Paragraph 00325
[5] Patent: US2007/111984, 2007, A1. Location in patent: Page/Page column 45
TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE manufacturers
- Product
- tetrahydro-2H-pyran-4-carboxamide 344329-76-6
- Price
- US $25.00/g
- Min. Order
- 1g
- Purity
- 99.96%
- Supply Ability
- 500ton
- Release date
- 2023-06-13
- Product
- TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE 344329-76-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-10-29
- Product
- 4-Carbamoyltetrahydropyran 344329-76-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 500kg
- Release date
- 2018-08-16