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Trimebutine maleate

Product Name
Trimebutine maleate
CAS No.
34140-59-5
Chemical Name
Trimebutine maleate
Synonyms
tm906;Foldox;Sakion;Modulon;Digerent;Spabucol;Trimedat;debridat;Salnatin;Selumito
CBNumber
CB5391172
Molecular Formula
C26H33NO9
Formula Weight
503.54
MOL File
34140-59-5.mol
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Trimebutine maleate Property

Melting point:
122-124°C
storage temp. 
2-8°C
solubility 
Slightly soluble in water, soluble in acetonitrile, sparingly soluble in acetone, slightly soluble in ethanol (96 per cent).
color 
White
InChIKey
FSRLGULMGJGKGI-BTJKTKAUSA-N
CAS DataBase Reference
34140-59-5(CAS DataBase Reference)
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Safety

Hazard Codes 
C
Risk Statements 
34
Safety Statements 
26-27-36/37/39-45
WGK Germany 
2
RTECS 
DI0360000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0001319
Product name
Trimebutine maleate
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0001319
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
PHR2804
Product name
Trimebutine maleate
Purity
certified reference material, pharmaceutical secondary standard
Packaging
50MG
Price
$316
Updated
2024/03/01
TRC
Product number
T795605
Product name
TrimebutineMaleateSalt
Packaging
1g
Price
$120
Updated
2021/12/16
Biosynth Carbosynth
Product number
FT28511
Product name
Trimebutine maleate
Packaging
250g
Price
$150
Updated
2021/12/16
Biosynth Carbosynth
Product number
FT28511
Product name
Trimebutine maleate
Packaging
500g
Price
$225
Updated
2021/12/16
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Trimebutine maleate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Trimebutine maleate is an antispasmodic that functions as an opioid receptor agonist. Its mechanism of action involves regulating bowel movements and enhancing gastrointestinal function. Trimebutine is commonly used in the treatment of Irritable bowel syndrome. It is also used to restart the movement of the gut after abdominal surgery and to prevent intestinal blockage (paralytic ileus).

Definition

ChEBI: Trimebutine maleate is a trihydroxybenzoic acid that is proposed as a spasmolytic with possible local anesthetic action for the treatment of gastrointestinal disorders.

Side effects

Possible side effects of trimebutine may include dry mouth, heartburn, nausea, diarrhea, constipation, drowsiness, dizziness, tiredness, indigestion, or headache. Other less frequent side effects are difficulty urinating, hearing loss, or painful breast enlargement. If any of these symptoms persist or worsen, please inform your doctor or pharmacist immediately.

References

https://www.drugs.com/medical-answers/trimebutine-3571789/
Trimebutine: abuse, addiction and overdose
https://myhealth.alberta.ca/Health/medications/Pages/conditions.aspx?hwid=fdb8090

Trimebutine maleate Preparation Products And Raw materials

Raw materials

Maleic acid Potassium borohydride Ammonium carbonate

Preparation Products

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View Lastest Price from Trimebutine maleate manufacturers

Henan Fengda Chemical Co., Ltd
Product
Trimebutine maleate 34140-59-5
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
airuikechemical co., ltd.
Product
trimebutine maleate 34140-59-5
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-09
WUHAN CIRCLE POWDER TECHNOLOGY CO.,LTD
Product
Trimebutine maleate 34140-59-5
Price
US $0.00/KG
Min. Order
100g
Purity
98%+
Supply Ability
100kg
Release date
2020-11-06

34140-59-5, Trimebutine maleateRelated Search:

Trimebutine Methyl 3,4,5-trimethoxybenzoate 1-Dimethylamino-2-phenylbutan-2-yl 3,4,5-trimethoxybenzoate DESMETHYL TRIMEBUTINE HCL ETHYL 3,5-DIMETHOXYBENZOATE Methyl 4,5-dimethoxy-3-hydroxybenzoate 2-DIMETHYLAMINO-2-METHYL-1-PROPANOL Methyl syringate 3,5-Dimethoxybenzoic acid Vanillyl butyl ether Trimebutine maleate 3-Hydroxy-4,5-dimethoxybenzoic acid 3,4,5-Trimethoxy benzoic acid Ethyl 3,4,5-trimethoxybenzoate 2-Phenylpropyl acetate fedotozine METHYL-BETA-D-GALACTOPYRANOSIDE Syringic acid

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  • 2'-PHENYL-2'-DIMETHYLAMINO-N-BUTYL 3,4,5-TRIMETHOXYBENZOATE MALEATE
  • 2-(dimethylamino)-2-phenylbutyl 3,4,5-trimethoxybenzoate maleate
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  • [1-ethyl-1-phenyl-2-(3,4,5-trimethoxybenzoyloxy)ethyl]dimethylammonium hydrogen maleate
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  • Benzoic acid, 3,4,5-trimethoxy-, b-(dimethylamino)-b-ethylphenethyl ester maleate (1:1) (8CI)
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