SIB 1757
- Product Name
- SIB 1757
- CAS No.
- 31993-01-8
- Chemical Name
- SIB 1757
- Synonyms
- SIB 1758;SIB 1757;6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;6-Methyl-2-(phenyldiazenyl)pyridin-3-ol;6-methyl-2-[(E)-phenyldiazenyl]pyridin-3;(E)-6-Methyl-2-(phenyldiazenyl)pyridin-3-ol;6-Methyl-2-[(E)-phenyldiazenyl]pyridin-3-ol;SIB-1757 6-METHYL-2-(PHENYLAZO)-3-PYRIDINOL;3-Pyridinol, 6-methyl-2-(2-phenyldiazenyl)-;SIB-1757,mGluR,SIB1757,Metabotropic glutamate receptors,inhibit,Inhibitor,SIB 1757
- CBNumber
- CB5404317
- Molecular Formula
- C12H11N3O
- Formula Weight
- 213.24
- MOL File
- 31993-01-8.mol
SIB 1757 Property
- storage temp.
- Store at RT
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- crystalline
- color
- red
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- S9186
- Product name
- SIB 1757
- Purity
- ≥99% (HPLC), crystalline
- Packaging
- 10MG
- Price
- $130
- Updated
- 2024/03/01
- Product number
- S9186
- Product name
- SIB 1757
- Purity
- ≥99% (HPLC), crystalline
- Packaging
- 50MG
- Price
- $511
- Updated
- 2022/05/15
- Product number
- S411005
- Product name
- SIB1757
- Packaging
- 25mg
- Price
- $140
- Updated
- 2021/12/16
- Product number
- 256663
- Product name
- SIB 1757
- Packaging
- 10mg
- Price
- $389
- Updated
- 2021/12/16
- Product number
- B6636
- Product name
- SIB1757
- Packaging
- 50mg
- Price
- $629
- Updated
- 2021/12/16
SIB 1757 Chemical Properties,Usage,Production
Uses
SIB 1757 is an antagonist for mGluR-5.
Definition
ChEBI: 6-methyl-2-(phenylhydrazinylidene)-3-pyridinone is a member of phenylhydrazines.
Biological Activity
A highly selective antagonist for the mGlu 5 metabotropic glutamate receptor subtype; displays an IC 50 value of 0.4 μ M at hmGlu 5 compared with > 30 μ M at hmGlu 1b , hmGlu 2 , hmGlu 4 , hmGlu 6 , hmGlu 7 and hmGlu 8 .
SIB 1757 Preparation Products And Raw materials
Raw materials
Preparation Products
SIB 1757 Suppliers
- Tel
- --
- Fax
- --
- customerservice@tocris.co.uk
- Country
- United Kingdom
- ProdList
- 5726
- Advantage
- 77
- Tel
- --
- Fax
- --
- kevinbanks@molekula.com
- Country
- United Kingdom
- ProdList
- 6140
- Advantage
- 66