ChemicalBook > CAS DataBase List > 5,6BETA-DIHYDRO PGI2

5,6BETA-DIHYDRO PGI2

Product Name
5,6BETA-DIHYDRO PGI2
CAS No.
62770-50-7
Chemical Name
5,6BETA-DIHYDRO PGI2
Synonyms
6β-Prostaglandin I1;5,6BETA-DIHYDRO PGI2;6BETA-PROSTAGLANDIN I1;5,6-dihydroprostacyclin;RJADQDXZYFCVHV-CBIPHORWSA-N;6S,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID;(6S,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid;Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6S,9α,11α,13E,15S)- (9CI)
CBNumber
CB5405420
Molecular Formula
C20H34O5
Formula Weight
354.48
MOL File
62770-50-7.mol
More
Less

5,6BETA-DIHYDRO PGI2 Property

storage temp. 
Store at -20°C
solubility 
DMF: >10 mg/ml; DMSO: >5 mg/ml; Ethanol: >20 mg/ml; PBS pH 7.2: >80 μg/ml
form 
A crystalline solid
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
18120
Product name
6β-Prostaglandin I1
Purity
≥99%
Packaging
1mg
Price
$64
Updated
2024/03/01
Cayman Chemical
Product number
18120
Product name
6β-Prostaglandin I1
Purity
≥99%
Packaging
5mg
Price
$280
Updated
2024/03/01
Cayman Chemical
Product number
18120
Product name
6β-Prostaglandin I1
Purity
≥99%
Packaging
10mg
Price
$497
Updated
2024/03/01
AK Scientific
Product number
1439AH
Product name
5,6beta-DihydroPGI2
Packaging
1mg
Price
$168
Updated
2021/12/16
AHH
Product number
MT-09763
Product name
5,6Beta-DihydroPGI2
Purity
99%
Packaging
0.01g
Price
$328
Updated
2021/12/16
More
Less

5,6BETA-DIHYDRO PGI2 Chemical Properties,Usage,Production

Description

6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions. 6β-PGI1 has a much longer half-life than PGI2, but a greatly reduced molar potency for receptor mediated function. 6β-PGI1 has a Kact for adenylate cyclase in NCB-20 cells of 4.2 μM compared with 18 nM for PGI2. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI2.1,2

Definition

ChEBI: 6-Prostaglandin I1 is a prostanoid.

References

1. Whittle, B.J.R., Moncada, S., Whiting, F., et al. Carbacyclin — a potent stable prostacyclin analogue for the inhibition of platelet aggregation Prostaglandins 19(4),605-627(1980).
2. Blair, I.A., Hensby, C.N., and MacDermot, J. Prostacyclin-dependent activation of adenylate cyclase in a neuronal somatic cell hybrid: Prostanoid structure-activity relationships Br. J. Pharmac. 69(3),519-525(1980).

5,6BETA-DIHYDRO PGI2 Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5,6BETA-DIHYDRO PGI2 Suppliers

China 6 United States 3 Global 9
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47

62770-50-7, 5,6BETA-DIHYDRO PGI2Related Search:

11-DEOXY PROSTAGLANDIN F1ALPHA 5,6BETA-DIHYDRO PGI2 PROSTAGLANDIN F1ALPHA 1,9ALPHA,11ALPHA,15S-TETRAHYDROXY-PROST-13E-ENE

  • 6BETA-PROSTAGLANDIN I1
  • 6S,9ALPHA-EPOXY-11ALPHA,15S-DIHYDROXY-PROST-13E-EN-1-OIC ACID
  • 5,6BETA-DIHYDRO PGI2
  • 5,6-dihydroprostacyclin
  • (6S,13E,15S)-6,9α-Epoxy-11α,15-dihydroxyprost-13-en-1-oic acid
  • RJADQDXZYFCVHV-CBIPHORWSA-N
  • Prost-13-en-1-oic acid, 6,9-epoxy-11,15-dihydroxy-, (6S,9α,11α,13E,15S)- (9CI)
  • 6β-Prostaglandin I1
  • 62770-50-7