ChemicalBook > CAS DataBase List > (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
- Product Name
- (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
- CAS No.
- 169505-93-5
- Chemical Name
- (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
- Synonyms
- RS-17053;RS17053HCl;RS 17053 HYDROCHLORIDE;RS 17053 hydrochloride (RS-17053);RS 17053 hydrochloride, 10 mM in DMSO;RS 17053 hydrochloride (Synonyms: RS-17053);Beta Receptor,Adrenergic Receptor,inhibit,RS 17053 hydrochloride,RS17053,RS 17053,Inhibitor;(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine)hydrochloride;(N-(2-(2-Cyclopropylmethoxyphenoxy)ethyl)-5-chloro-(a,a)-dimethyl-(1H)-indole-3-ethanamine)hydrochloride;(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
- CBNumber
- CB5417674
- Molecular Formula
- C24H30Cl2N2O2
- Formula Weight
- 449.42
- MOL File
- 169505-93-5.mol
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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Property
- storage temp.
- Store at RT
- solubility
- insoluble in ethanol; <22.47mg/ml in DMSO
- form
- solid
- color
- White
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N-Bromosuccinimide Price
Tocris
- Product number
- 0985
- Product name
- RS17053hydrochloride
- Packaging
- 10
- Price
- $124
- Updated
- 2021/12/16
Tocris
- Product number
- 0985
- Product name
- RS17053hydrochloride
- Packaging
- 50
- Price
- $520
- Updated
- 2021/12/16
TRC
- Product number
- R701008
- Product name
- RS17053Hydrochloride
- Packaging
- 50mg
- Price
- $610
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0021176
- Product name
- RS17053hydrochloride
- Purity
- 99.25%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-0021176
- Product name
- RS17053hydrochloride
- Purity
- 99.25%
- Packaging
- 10mg
- Price
- $120
- Updated
- 2021/12/16
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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Chemical Properties,Usage,Production
Uses
RS 17053 Hydrochloride is a selective a1A adrenoceptor antagonist.
Biological Activity
α 1A -adrenoceptor antagonist, with very high affinity for α 1A receptors (pK i and pA 2 estimates of 9.1-9.9) and a 30-100 fold selectivity over the α 1B and α 1D subtypes (pK i and pA 2 estimates 7.7-7.8).
in vivo
RS 17053 hydrochloride has a rapid onset of action, and a duration of action exceeding 60 min. RS 17053 hydrochloride pretreatment significantly alteres food intake [F(4, 132) 5 6.28, p , 0.0001]. 10 mg/kg RS-17053 significantly suppresses food intake[2].
storage
Store at RT
(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Suppliers
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169505-93-5, (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDERelated Search:
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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE