(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE

Product Name: (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
CAS No.: 169505-93-5
Chemical Name: (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
Synonyms: RS-17053;RS17053HCl;RS 17053 HYDROCHLORIDE;RS 17053 hydrochloride (RS-17053);RS 17053 hydrochloride, 10 mM in DMSO;RS 17053 hydrochloride (Synonyms: RS-17053);Beta Receptor,Adrenergic Receptor,inhibit,RS 17053 hydrochloride,RS17053,RS 17053,Inhibitor;(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine)hydrochloride;(N-(2-(2-Cyclopropylmethoxyphenoxy)ethyl)-5-chloro-(a,a)-dimethyl-(1H)-indole-3-ethanamine)hydrochloride;(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
CBNumber: CB5417674
Molecular Formula: C24H30Cl2N2O2
Formula Weight: 449.42
MOL File: 169505-93-5.mol

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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Property

storage temp.: Store at RT
solubility: insoluble in ethanol; <22.47mg/ml in DMSO
form: solid
color: White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 0985
Product name: RS17053hydrochloride
Packaging: 10
Price: $124
Updated: 2021/12/16

Tocris

Product number: 0985
Product name: RS17053hydrochloride
Packaging: 50
Price: $520
Updated: 2021/12/16

TRC

Product number: R701008
Product name: RS17053Hydrochloride
Packaging: 50mg
Price: $610
Updated: 2021/12/16

ChemScene

Product number: CS-0021176
Product name: RS17053hydrochloride
Purity: 99.25%
Packaging: 5mg
Price: $70
Updated: 2021/12/16

ChemScene

Product number: CS-0021176
Product name: RS17053hydrochloride
Purity: 99.25%
Packaging: 10mg
Price: $120
Updated: 2021/12/16

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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

RS 17053 Hydrochloride is a selective a1A adrenoceptor antagonist.

Biological Activity

α 1A -adrenoceptor antagonist, with very high affinity for α 1A receptors (pK i and pA 2 estimates of 9.1-9.9) and a 30-100 fold selectivity over the α 1B and α 1D subtypes (pK i and pA 2 estimates 7.7-7.8).

in vivo

RS 17053 hydrochloride has a rapid onset of action, and a duration of action exceeding 60 min. RS 17053 hydrochloride pretreatment significantly alteres food intake [F(4, 132) 5 6.28, p , 0.0001]. 10 mg/kg RS-17053 significantly suppresses food intake^[2].

storage

Store at RT

(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE Suppliers

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169505-93-5, (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDERelated Search:

N,N'-Ethylenebis(stearamide) Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE

(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE

RS 17053 HYDROCHLORIDE

RS 17053 hydrochloride (RS-17053)

RS 17053 hydrochloride (Synonyms: RS-17053)

(N-(2-(2-Cyclopropylmethoxyphenoxy)ethyl)-5-chloro-(a,a)-dimethyl-(1H)-indole-3-ethanamine)hydrochloride

RS17053HCl

(N-[2-(2-Cyclopropylmethoxyphenoxy)ethyl]-5-chloro-α,α-dimethyl-1H-indole-3-ethanamine)hydrochloride

RS-17053

Beta Receptor,Adrenergic Receptor,inhibit,RS 17053 hydrochloride,RS17053,RS 17053,Inhibitor

RS 17053 hydrochloride, 10 mM in DMSO

169505-93-5

C24H29N2O2ClHCl