ChemicalBook > CAS DataBase List > 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE

4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE

Product Name
4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
CAS No.
26956-43-4
Chemical Name
4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
Synonyms
108561;Furo[3,2-c]pyridin-4-ol;5H-Furo[3,2-c]pyridin-4-one;FURO[3,2-C]PYRIDIN-4(5H)-ONE;4H,5H-furo[3,2-c]pyridin-4-one;4,5-Dihyro-4-Oxofuro[3,2]Pyridine;4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE;4-OXO-4,5-DIHYDROFURO[3,2-C]PYRIDINE;Furo[3,2-c]pyridin-4(5H)-one (8CI, 9CI, ACI);4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE ISO 9001：2015 REACH
CBNumber
CB5428634
Molecular Formula
C7H5NO2
Formula Weight
135.12
MOL File
26956-43-4.mol
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4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Property

Melting point:
202-204 °C
Boiling point:
372.8±42.0 °C(Predicted)
Density 
1.288±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
12.11±0.20(Predicted)
Appearance
Light yellow to yellow Solid
InChI
InChI=1S/C7H5NO2/c9-7-5-2-4-10-6(5)1-3-8-7/h1-4H,(H,8,9)
InChIKey
FYNCIYHECMWXPK-UHFFFAOYSA-N
SMILES
C1(=O)NC=CC2OC=CC1=2
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
2811
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
2934999090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CVT00122
Product name
Furo[3,2-c]pyridin-4-ol
Packaging
1g
Price
$958
Updated
2023/06/20
TRC
Product number
F864853
Product name
Furo[3,2-c]pyridin-4(5H)-one
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
070257
Product name
Furo[3,2-c]pyridin-4(5H)-one
Purity
95%
Packaging
1g
Price
$63
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-1-E2
Product name
Furo[3,2-c]pyridin-4(5H)-one
Packaging
1g
Price
$72
Updated
2021/12/16
Biosynth Carbosynth
Product number
FD139854
Product name
4,5-dihydro-4-oxofuro[3,2-c]pyridine
Packaging
500mg
Price
$160
Updated
2021/12/16
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4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Chemical Properties,Usage,Production

Synthesis

119924-26-4

26956-43-4

The general procedure for the synthesis of 4,5-dihydro-4-oxofuro[3,2]pyridine from (E)-3-(furan-2-yl)acryloyl azide was as follows: (E)-3-(furan-2-yl)acryloyl azide (150 g, 920 mmol) was added to toluene (800 mL) preheated to 100 °C and the reaction mixture was stirred for 30 min. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was dissolved in o-dichlorobenzene (800 mL) and iodine (1 g) was added as a catalyst. The reaction mixture was stirred at 180 °C for 2 h, followed by evaporation under reduced pressure to remove the solvent. The residue was dissolved in methanol, the precipitate was collected by filtration and the filtrate was concentrated under reduced pressure. Finally, the residue was washed with diisopropyl ether to afford the target product 4,5-dihydro-4-oxofuro[3,2]pyridine (100 g, 80% yield). The product was characterized by 1H-NMR (DMSO-d6): δ 6.85 (1H, dd, J = 7.1, 1.0 Hz), 6.92 (1H, dd, J = 1.9, 1.0 Hz), 7.29 (1H, d, J = 7.1 Hz), 7.86 (1H, d, J = 1.9 Hz), 11.42 (1H, brs).

References

[1] Patent: EP2100895, 2009, A1. Location in patent: Page/Page column 44
[2] Patent: WO2013/163244, 2013, A1. Location in patent: Paragraph 00273
[3] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 146
[4] Patent: WO2004/100947, 2004, A2. Location in patent: Page 20-21; 16
[5] Patent: WO2005/67900, 2005, A2. Location in patent: Page/Page column 39-40

4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE Suppliers

China 89 Germany 3 India 1 The Netherlands 1 United Kingdom 4 United States 12 Global 110
Specs
Tel
--
Fax
--
Email
info@specs.net
Country
The Netherlands
ProdList
6833
Advantage
70
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View Lastest Price from 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE 26956-43-4
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12
Career Henan Chemical Co
Product
4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE 26956-43-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-11

26956-43-4, 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINERelated Search:

Furo[3,4-c]pyridin-1(3h)-one furo[3,2-b]pyridine 4-(2-Nitrophenyl)-2-methyl-5,7-dihydro-5-oxofuro[3,4-b]pyridine-3-carboxylic acid methyl ester 4-(2,3-Dichlorophenyl)-2-methyl-5,7-dihydro-5-oxofuro[3,4-b]pyridine-3-carboxylic acid 2-[2-(Trifluoromethyl)phenyl]-4-methyl-5,7-dihydro-5-oxofuro[3,4-b]pyridine-3-carboxylic acid methyl ester 5-AMINO-6-METHYLFURO[3,2-C]PYRIDIN-4(5H)-ONE 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE SALOR-INT L299502-1EA SALOR-INT L299510-1EA SALOR-INT L299529-1EA

  • FURO[3,2-C]PYRIDIN-4(5H)-ONE
  • 4-OXO-4,5-DIHYDROFURO[3,2-C]PYRIDINE
  • 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE
  • 4,5-Dihyro-4-Oxofuro[3,2]Pyridine
  • 4H,5H-furo[3,2-c]pyridin-4-one
  • 5H-Furo[3,2-c]pyridin-4-one
  • Furo[3,2-c]pyridin-4-ol
  • 108561
  • 4,5-DIHYDRO-4-OXOFURO[3,2-C]PYRIDINE ISO 9001：2015 REACH
  • Furo[3,2-c]pyridin-4(5H)-one (8CI, 9CI, ACI)
  • 26956-43-4
  • Fused Ring Systems