ChemicalBook > CAS DataBase List > ACETYL-DL-CARNITINE HYDROCHLORIDE

ACETYL-DL-CARNITINE HYDROCHLORIDE

Product Name
ACETYL-DL-CARNITINE HYDROCHLORIDE
CAS No.
2504-11-2
Chemical Name
ACETYL-DL-CARNITINE HYDROCHLORIDE
Synonyms
TIMTEC-BB SBB003214;Acetyl-DL-carnitineHCl;acetyldl-carnitinechloride;d,l-acetylcarnitin-chlorid;(±)-Acetylcarnitine chloride;(+/-)-ACETYLCARNITINE CHLORIDE;ACETYL-DL-CARNITINE HYDROCHLORIDE;acetyl-dl-carnitine hcl crystalline;Acetyl-DL-carnitine hydrochloride;Acetyl-DL-carnitinehydrochloridecrystalline
CBNumber
CB5440058
Molecular Formula
C9H18ClNO4
Formula Weight
239.7
MOL File
2504-11-2.mol
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ACETYL-DL-CARNITINE HYDROCHLORIDE Property

Melting point:
181 - 183°C
storage temp. 
-20°C
solubility 
DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Water Solubility 
Soluble to 100 mM in water
Stability:
Hygroscopic
CAS DataBase Reference
2504-11-2(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
BP2979200
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A1509
Product name
Acetyl-DL-carnitine hydrochloride
Packaging
250mg
Price
$177
Updated
2025/07/31
Sigma-Aldrich
Product number
A1509
Product name
Acetyl-DL-carnitine hydrochloride
Packaging
1g
Price
$501
Updated
2025/07/31
TRC
Product number
A172003
Product name
(±)-AcetylcarnitineChloride
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
A172003
Product name
(±)-AcetylcarnitineChloride
Packaging
100mg
Price
$180
Updated
2021/12/16
ApexBio Technology
Product number
B6273
Product name
(±)-Acetylcarnitinechloride
Packaging
100mg
Price
$125
Updated
2021/12/16
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ACETYL-DL-CARNITINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

(±)-Acetylcarnitine Chloride is a drug absorption-enhancing agent in the gastrointestinal tract.

Biological Activity

(±)-acetylcarnitine chloride is an agonist for cholinergic.acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-acetylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3].

Biochem/physiol Actions

Weak cholinergic receptor agonist; intermediate in lipid metabolism.

in vivo

In rats, the infusion of 2 mg (±)-Acetylcarnitine chloride decreases blood flow through the hind limb vasculature 50%. (±)-Acetylcarnitine chloride also potentiates the inhibitory effect of adrenaline on the isolated rabbit duodenum[3].

Purification Methods

Recrystallise the chloride from isopropanol. Dry it over P2O5 under high vacuum. The S-betaine crystallises from EtOH/Et2O with m 145o(dec) and is hygroscopic; it has [] D -19.5o (c 6, H2O). [Krimberg & Wittandt Biochem Z 251 231 1932, Strack et al. Z Physiol Chem 238 191 1936, Beilstein 4 III 1630, 1632.]

ACETYL-DL-CARNITINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ACETYL-DL-CARNITINE HYDROCHLORIDE Suppliers

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View Lastest Price from ACETYL-DL-CARNITINE HYDROCHLORIDE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
ACETYL-DL-CARNITINE HYDROCHLORIDE 2504-11-2
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-04-01

2504-11-2, ACETYL-DL-CARNITINE HYDROCHLORIDERelated Search:


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  • Amino Acids and Peptides
  • Biochemicals and Reagents
  • BioChemical
  • A - H
  • Modified Amino Acids
  • Cholinergics
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