ACETYL-DL-CARNITINE HYDROCHLORIDE

Product Name: ACETYL-DL-CARNITINE HYDROCHLORIDE
CAS No.: 2504-11-2
Chemical Name: ACETYL-DL-CARNITINE HYDROCHLORIDE
Synonyms: TIMTEC-BB SBB003214;Acetyl-DL-carnitineHCl;acetyldl-carnitinechloride;d,l-acetylcarnitin-chlorid;(+/-)-ACETYLCARNITINE CHLORIDE;ACETYL-DL-CARNITINE HYDROCHLORIDE;acetyl-dl-carnitine hcl crystalline;Acetyl-DL-carnitinehydrochloridecrystalline;(±)-Acetylcarnitine chloride, cholinergic agonist;(RS)-3-Acetoxy-4-(trimetylammino)butyrate hydrochloride
CBNumber: CB5440058
Molecular Formula: C9H18ClNO4
Formula Weight: 239.7
MOL File: 2504-11-2.mol

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ACETYL-DL-CARNITINE HYDROCHLORIDE Property

Melting point:: 181 - 183°C
storage temp.: -20°C
solubility: DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form: Solid
color: White to Off-White
Water Solubility: Soluble to 100 mM in water
Stability:: Hygroscopic
CAS DataBase Reference: 2504-11-2(CAS DataBase Reference)

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Safety

WGK Germany: 3
RTECS: BP2979200

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A1509
Product name: Acetyl-DL-carnitine hydrochloride
Packaging: 250mg
Price: $165
Updated: 2024/03/01

Sigma-Aldrich

Product number: A1509
Product name: Acetyl-DL-carnitine hydrochloride
Packaging: 1g
Price: $469
Updated: 2024/03/01

TRC

Product number: A172003
Product name: (±)-AcetylcarnitineChloride
Packaging: 100mg
Price: $180
Updated: 2021/12/16

TRC

Product number: A172003
Product name: (±)-AcetylcarnitineChloride
Packaging: 10mg
Price: $45
Updated: 2021/12/16

ApexBio Technology

Product number: B6273
Product name: (±)-Acetylcarnitinechloride
Packaging: 100mg
Price: $125
Updated: 2021/12/16

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ACETYL-DL-CARNITINE HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

(±)-Acetylcarnitine Chloride is a drug absorption-enhancing agent in the gastrointestinal tract.

Biological Activity

(±)-acetylcarnitine chloride is an agonist for cholinergic.acetylcholine receptor (achr) is an integral membrane protein receptor for acetylcholine. there are two kinds of achrs: nicotinic acetylcholine receptors and muscarinic acetylcholine receptors.(±)-acetylcarnitine chloride is a cholinergic agonist and an intermediate in lipid metabolism [1]. in retinal ganglion cells, acetylcarnitine and acetylcholine inhibited gabaergic responses to exogenous gaba and gabaergic inhibitory postsynaptic currents [2].in dogs with coronary ligation, (-)-carnitine chloride (lcc) (300 mg/kg) and acetyl (-)-carnitine chloride (alcc) (300 mg/kg) inhibited the ventricular arrhythmia. also, lcc and alcc improved oxidative phosphorylation rate and the mitochondrial function [1]. in the mouse hot plate test, acetyl-l-carnitine (alcar) (100 mg/kg) exhibited analgesia. while, u-73122 and neomycin (the phospholipase c (plc) inhibitors) blocked the increase of the pain threshold induced by alcar. licl that impairing phosphatidylinositol synthesis antagonized the antinociception in a dose-dependent way. pma and pdbu (pkc activators) blocked the increase of the pain threshold in a dose-dependent way. these results suggested that alcar analgesia required the participation of the plc-ip3 pathway [3].

Biochem/physiol Actions

Weak cholinergic receptor agonist; intermediate in lipid metabolism.

Purification Methods

Recrystallise the chloride from isopropanol. Dry it over P2O5 under high vacuum. The S-betaine crystallises from EtOH/Et2O with m 145o(dec) and is hygroscopic; it has [] D -19.5o (c 6, H2O). [Krimberg & Wittandt Biochem Z 251 231 1932, Strack et al. Z Physiol Chem 238 191 1936, Beilstein 4 III 1630, 1632.]

ACETYL-DL-CARNITINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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ACETYL-DL-CARNITINE HYDROCHLORIDE Suppliers

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2504-11-2, ACETYL-DL-CARNITINE HYDROCHLORIDERelated Search:

Palmitoyl-L-Carnitine Chloride HEXANOYL-L-CARNITINE CHLORIDE (+/-)-OCTANOYLCARNITINE CHLORIDE LINOLEOYL-L-CARNITINE CHLORIDE MYRISTOYL-L-CARNITINE CHLORIDE O-Acetyl-L-carnitine hydrochloride DECANOYL-L-CARNITINE CHLORIDE BUTYRYL-L-CARNITINE CHLORIDE ACETYL-D-CARNITINE CHLORIDE LAUROYL-L-CARNITINE CHLORIDE (3-CARBOXYPROPYL)TRIMETHYLAMMONIUM CHLORIDE DL-Carnitine L(-)-Carnitine hydrochloride L-carnitine DL-Carnitine hydrochloride ACETYL-DL-CARNITINE HYDROCHLORIDE DL-CAPROYLCARNITINE CHLORIDE DL-STEAROYL CARNITINE CHLORIDE

(+/-)-3-ACETOXY-4-(TRIMETHYLAMMONIO)BUTYRATE HYDROCHLORIDE

[+/-]-3-ACETOXY-4-(TRIMETHYLAMMONIO)BUTYRATE HYDROCHLORIDE

ACETYL-DL-CARNITINE HYDROCHLORIDE

(+/-)-ACETYLCARNITINE CHLORIDE

acetyl-dl-carnitine hcl crystalline

(±)-(2-acetoxy-3-carboxypropyl)trimethylammonium chloride

Acetyl-DL-carnitineHCl

Acetyl-DL-carnitinehydrochloridecrystalline

(RS)-3-Acetoxy-4-(trimetylammino)butyrate hydrochloride

(2-acetoxy-4-hydroxy-4-keto-butyl)-trimethyl-ammonium chloride

(2-acetyloxy-4-hydroxy-4-oxo-butyl)-trimethyl-azanium chloride

(2-acetyloxy-4-hydroxy-4-oxobutyl)-trimethylazanium chloride

(+-)-(3-carboxy-2-hydroxypropyl)trimethylammoniumchlorideacetate

(3-carboxy-2-hydroxypropyl)trimethyl-,chloride,acetate,(+-)-ammoniu

2-(acetyloxy)-3-carboxy-n,n,n-trimethyl-,chloride,(+-)-1-propanaminiu

acetyldl-carnitinechloride

d,l-acetylcarnitin-chlorid

TIMTEC-BB SBB003214

(2-acetyloxy-3-carboxypropyl)-trimethylazanium,chloride

(±)-Acetylcarnitine chloride, cholinergic agonist

2504-11-2

C9H18CINO4

Amino Acids and Peptides

Biochemicals and Reagents

BioChemical

A - H

Modified Amino Acids

Cholinergics

Lipid signaling