ChemicalBook > CAS DataBase List > 4-HYDROXY-6-IODOQUINOLINE

4-HYDROXY-6-IODOQUINOLINE

Product Name
4-HYDROXY-6-IODOQUINOLINE
CAS No.
342617-07-6
Chemical Name
4-HYDROXY-6-IODOQUINOLINE
Synonyms
BUTTPARK 100\01-54;6-Iodo-4-quinolinol;6-IODOQUINOLIN-4-OL;4-Quinolinol, 6-iodo-;6-iodo-1H-quinolin-4-one;6-IODOQUINOLIN-4(1H)-ONE;4-HYDROXY-6-IODOQUINOLINE;4-Hyrdroxy-6-iodoquinoline
CBNumber
CB5447961
Molecular Formula
C9H6INO
Formula Weight
271.05
MOL File
342617-07-6.mol
More
Less

4-HYDROXY-6-IODOQUINOLINE Property

Boiling point:
394℃
Density 
1.974
Flash point:
192℃
storage temp. 
2-8°C(protect from light)
pka
3.85±0.40(Predicted)
Appearance
White to off-white Solid
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

More
Less

N-Bromosuccinimide Price

TRC
Product number
I737140
Product name
6-Iodoquinolin-4-ol
Packaging
100mg
Price
$75
Updated
2021/12/16
Usbiological
Product number
279808
Product name
4-Hyrdroxy-6-iodoquinoline
Packaging
1g
Price
$432
Updated
2021/12/16
AK Scientific
Product number
V0843
Product name
4-Hyrdroxy-6-iodoquinoline
Packaging
5g
Price
$110
Updated
2021/12/16
ChemScene
Product number
CS-D0866
Product name
4-HYDROXY-6-IODOQUINOLINE
Purity
≥97.0%
Packaging
5g
Price
$132
Updated
2021/12/16
AK Scientific
Product number
V0843
Product name
4-Hyrdroxy-6-iodoquinoline
Packaging
10g
Price
$175
Updated
2021/12/16
More
Less

4-HYDROXY-6-IODOQUINOLINE Chemical Properties,Usage,Production

Synthesis

909344-69-0

342617-07-6

The reaction was carried out by batchwise addition of 5-{[(4-iodophenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6-dione (120 g) in diphenyl ether (1.3 L, 8.0 mol) at 240 °C for 1.5 hours. After completion of the reaction, the mixture was cooled to room temperature and poured into 1.5 L of hexane. The resulting suspension was filtered and the filter cake was broken and washed with hexane (2 x 500 mL). The solid was dried under vacuum to afford 6-iodo-4-hydroxyquinoline as a brown solid (80 g, 82% yield). The product was characterized by 1H NMR (400 MHz, DMSO-d6): δ11.89 (d, J=4.0 Hz, 1H), 8.36 (d, J=2.3 Hz, 1H), 7.89-7.98 (m, 2H), 7.37 (d, J=8.6 Hz, 1H), 6.07 (dd, J=7.5,1.1 Hz, 1H); mass spectra (m /z) 272.0 (M+H+).

References

[1] Patent: US2012/41024, 2012, A1. Location in patent: Page/Page column 8; 10; 16
[2] Patent: EP2566477, 2015, B1. Location in patent: Paragraph 0157; 0159
[3] Journal of Medicinal Chemistry, 2016, vol. 59, # 10, p. 4867 - 4880

4-HYDROXY-6-IODOQUINOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

4-HYDROXY-6-IODOQUINOLINE Suppliers

Butt Park Ltd.
Tel
--
Fax
--
Email
113707.50@compuserve.com
Country
United Kingdom
ProdList
6078
Advantage
30
Ubichem plc
Tel
--
Fax
--
Email
sales@ubichem.com
Country
United Kingdom
ProdList
1567
Advantage
65
More
Less

View Lastest Price from 4-HYDROXY-6-IODOQUINOLINE manufacturers

Career Henan Chemical Co
Product
4-HYDROXY-6-IODOQUINOLINE 342617-07-6
Price
US $1.00/KG
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-10