ChemicalBook > CAS DataBase List > 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER

Product Name
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
CAS No.
39731-05-0
Chemical Name
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Synonyms
SDZ 21009;Carpindolol;Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate;4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester;4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste;4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER;1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester
CBNumber
CB5448519
Molecular Formula
C19H28N2O4
Formula Weight
348.44
MOL File
39731-05-0.mol
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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Property

Boiling point:
529.8±50.0 °C(Predicted)
Density 
1.150±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
Soluble to 100 mM in ethanol and to 100 mM in DMSO
form 
Powder
pka
pKa 8.75 (Uncertain)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1516
Product name
SDZ21009
Packaging
50
Price
$665
Updated
2021/12/16
Usbiological
Product number
256645
Product name
SDZ 21009
Packaging
10mg
Price
$466
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0010559
Product name
4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$505.57
Updated
2021/12/16
ApexBio Technology
Product number
B6773
Product name
SDZ21009
Packaging
10mg
Price
$314
Updated
2021/12/16
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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Chemical Properties,Usage,Production

Uses

SDZ 21009 is a 5-HT1A/1B antagonist.

Definition

ChEBI: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid propan-2-yl ester is an isopropyl ester and an indolyl carboxylate ester.

Biological Activity

β -adrenoceptor and 5-HT 1A/1B receptor antagonist. pK B /pA 2 values are 8.3 and 8.0 for 5-HT 1A and 5-HT 1B receptors respectively. Centrally active following systemic administration in vivo .

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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3bsc@sina.com
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China
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ApexBio Technology
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39731-05-0, 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTERRelated Search:


  • SDZ 21009
  • 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
  • Carpindolol
  • 4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester
  • 4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste
  • 1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester
  • Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate
  • 39731-05-0
  • C19H28N2O4