4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER

Product Name: 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
CAS No.: 39731-05-0
Chemical Name: 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Synonyms: SDZ 21009;Carpindolol;Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate;4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester;4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste;4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER;1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester
CBNumber: CB5448519
Molecular Formula: C19H28N2O4
Formula Weight: 348.44
MOL File: 39731-05-0.mol

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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Property

Boiling point:: 529.8±50.0 °C(Predicted)
Density: 1.150±0.06 g/cm3(Predicted)
storage temp.: Store at RT
solubility: Soluble to 100 mM in ethanol and to 100 mM in DMSO
form: Powder
pka: pKa 8.75 (Uncertain)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1516
Product name: SDZ21009
Packaging: 50
Price: $665
Updated: 2021/12/16

Usbiological

Product number: 256645
Product name: SDZ 21009
Packaging: 10mg
Price: $466
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0010559
Product name: 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER
Purity: 95.00%
Packaging: 5MG
Price: $505.57
Updated: 2021/12/16

ApexBio Technology

Product number: B6773
Product name: SDZ21009
Packaging: 10mg
Price: $314
Updated: 2021/12/16

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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Chemical Properties,Usage,Production

Uses

SDZ 21009 is a 5-HT1A/1B antagonist.

Definition

ChEBI: 4-[3-(tert-butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid propan-2-yl ester is an isopropyl ester and an indolyl carboxylate ester.

Biological Activity

β -adrenoceptor and 5-HT 1A/1B receptor antagonist. pK B /pA 2 values are 8.3 and 8.0 for 5-HT 1A and 5-HT 1B receptors respectively. Centrally active following systemic administration in vivo .

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Suppliers

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39731-05-0, 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTERRelated Search:

4-Methoxy-1H-indole-2-carboxylic acid rac Mepindolol-d7 4-Hydroxy-2-methylindole METHYL 4-METHOXY-2-INDOLECARBOXYLATE 4-methoxy-2-methyl-1H-indole 4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER Pindolol

SDZ 21009

4-[3-[(1,1-DIMETHYLETHYL)AMINO]-2-HYDROXYPROPOXY]-1H-INDOLE-2-CARBOXYLIC ACID, 1-METHYLETHYL ESTER

Carpindolol

4-[3-(tert-Butylamino)-2-hydroxypropoxy]-1H-indole-2-carboxylic acid isopropyl ester

4-[3-[(1,1-Dimethylethyl)amino]-2-hydroxypropoxy]-1H-indole-2-carboxylicacid,1-methylethyleste

1H-Indole-2-carboxylic acid, 4-[3-[(1,1-dimethylethyl)amino]-2-hydroxypropoxy]-, 1-methylethyl ester

Isopropyl 4-(3-(tert-butylamino)-2-hydroxypropoxy)-1H-indole-2-carboxylate

39731-05-0

C19H28N2O4