ChemicalBook > CAS DataBase List > 3-Benzyloxybenzaldehyde

3-Benzyloxybenzaldehyde

Product Name
3-Benzyloxybenzaldehyde
CAS No.
1700-37-4
Chemical Name
3-Benzyloxybenzaldehyde
Synonyms
ASISCHEM N42207;AKOS BBS-00003155;3-Benzyloxybenzaldeh;3-BENZYLOXYBENZALDEHYDE;M-BENZYLOXYBENZALDEHYDE;Metaraminol Impurity 34;3-Benzyloxybenzaldehyde98%;3-Benzyloxybenzaldehyde 98%;3-Benzyloxybenzaldehyde >Benzaldehyde, m-(benzyloxy)-
CBNumber
CB5459377
Molecular Formula
C14H12O2
Formula Weight
212.24
MOL File
1700-37-4.mol
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3-Benzyloxybenzaldehyde Property

Melting point:
56-58 °C(lit.)
Boiling point:
180°C 0,08mm
Density 
1.1035 (rough estimate)
refractive index 
1.6000 (estimate)
Flash point:
180°C/0.08mm
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Fine Crystalline Powder
color 
White to light beige
Water Solubility 
Soluble in water 38.87 mg/L @ 25°C.
Sensitive 
Air Sensitive
BRN 
1956589
LogP
2.960 (est)
CAS DataBase Reference
1700-37-4(CAS DataBase Reference)
NIST Chemistry Reference
Benzyl 3-formylphenyl ether(1700-37-4)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29124990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B27005
Product name
3-Benzyloxybenzaldehyde
Purity
98%
Packaging
5g
Price
$51.4
Updated
2023/01/07
Sigma-Aldrich
Product number
B27005
Product name
3-Benzyloxybenzaldehyde
Purity
98%
Packaging
25g
Price
$170
Updated
2023/01/07
TCI Chemical
Product number
B2400
Product name
3-Benzyloxybenzaldehyde
Purity
>98.0%(GC)
Packaging
25g
Price
$83
Updated
2025/07/31
TRC
Product number
B285460
Product name
3-Benzyloxybenzaldehyde
Packaging
10g
Price
$100
Updated
2021/12/16
SynQuest Laboratories
Product number
2615-1-62
Product name
3-(Benzyloxy)benzaldehyde
Purity
98%
Packaging
100g
Price
$188
Updated
2021/12/16
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3-Benzyloxybenzaldehyde Chemical Properties,Usage,Production

Chemical Properties

WHITE TO LIGHT BEIGE FINE CRYSTALLINE POWDER

Uses

3-Benzyloxybenzaldehyde is used as a pharmaceutical intermediate. It activates the adenyl cyclase.

Synthesis

100-39-0

100-83-4

1700-37-4

The general procedure for the synthesis of 3-(benzyloxy)benzaldehyde from benzyl bromide and m-hydroxybenzaldehyde was as follows: m-hydroxybenzaldehyde (3 g, 24.6 mmol) and anhydrous potassium carbonate (10.2 g, 73.8 mmol) were suspended in N,N-dimethylformamide (60 mL). Benzyl bromide (3.21 mL, 27.1 mmol) was added dropwise to this suspension and the reaction was stirred at room temperature for 14 hours. Upon completion of the reaction, the reaction mixture was poured into a mixture of ethyl acetate and water for liquid-liquid partitioning. The organic phase was separated, washed three times with water, the organic phase was dried with anhydrous magnesium sulfate, and the desiccant was removed by filtration. The filtrate was concentrated under reduced pressure and the resulting crude product was purified by silica gel column chromatography with an eluent ratio of heptane:ethyl acetate (4:1 to 1:1 gradient elution) to afford the target compound 3-(benzyloxy)benzaldehyde (5.16 g, 99% yield). The product was characterized by 1H-NMR (CDCl3) with the following chemical shift δ (ppm): 5.13 (2H, s, -OCH2-), 7.24-7.25 (1H, m, aryl ring H), 7.35-7.49 (8H, m, aryl ring H), 9.98 (1H, s, -CHO).

References

[1] Journal of the American Chemical Society, 1994, vol. 116, # 18, p. 8402 - 8403
[2] Journal of Medicinal Chemistry, 2015, vol. 58, # 7, p. 3188 - 3208
[3] Patent: US2007/105904, 2007, A1. Location in patent: Page/Page column 112
[4] Molecules, 2010, vol. 15, # 11, p. 7971 - 7984
[5] Journal of the American Chemical Society, 2001, vol. 123, # 22, p. 5382 - 5383

3-Benzyloxybenzaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Benzyloxybenzaldehyde Suppliers

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View Lastest Price from 3-Benzyloxybenzaldehyde manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
3-Benzyloxybenzaldehyde 1700-37-4
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15
Career Henan Chemical Co
Product
3-Benzyloxybenzaldehyde 1700-37-4
Price
US $5.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1ton
Release date
2019-08-05

1700-37-4, 3-BenzyloxybenzaldehydeRelated Search:


  • Benzaldehyde, 3-(phenylmethoxy)-
  • Benzaldehyde, m-(benzyloxy)-
  • M-BENZYLOXYBENZALDEHYDE
  • 3-BENZYLOXYBENZALDEHYDE
  • AKOS BBS-00003155
  • ASISCHEM N42207
  • 3-Benzyloxybenzaldehyde98%
  • 3-Benzyloxybenzaldehyde 98%
  • 3-(Phenylmethoxy)benzaldehyde
  • 3-Benzyloxybenzaldeh
  • 3-BENZYLOXYBENZALDEHYDE FOR SYNTHESIS
  • 1-cyano-N,N-dimethylformamide
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  • 1700-37-4
  • ALDEHYDE
  • C10 to C21
  • Carbonyl Compounds
  • Building Blocks
  • Aldehydes
  • Organic Building Blocks
  • Aromatic Aldehydes & Derivatives (substituted)
  • Aldehydes
  • C10 to C21
  • Carbonyl Compounds