HUWENTOXIN IV

Product Name: HUWENTOXIN IV
CAS No.: 526224-73-7
Chemical Name: HUWENTOXIN IV
Synonyms: HUWENTOXIN IV;HUWENTOXIN IV USP/EP/BP
CBNumber: CB54730704
Molecular Formula: C174H278N52O51S6
Formula Weight: 0
MOL File: Mol file

More

Less

HUWENTOXIN IV Property

storage temp.: Store at -20°C
form: Powder
Water Solubility: Soluble to 1 mg/ml in water

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Tocris

Product number: 4718
Product name: HuwentoxinIV
Packaging: 100U
Price: $220
Updated: 2021/12/16

Usbiological

Product number: 255471
Product name: Huwentoxin IV
Packaging: 100ug
Price: $495
Updated: 2021/12/16

ApexBio Technology

Product number: B5693
Product name: HuwentoxinIV
Packaging: 100ug
Price: $339
Updated: 2021/12/16

More

Less

HUWENTOXIN IV Chemical Properties,Usage,Production

Uses

Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively. Huwentoxin-IV preferentially blocks peripheral nerve subtype Nav1.7 by binding neurotoxin receptor site 4. Huwentoxin-IV has analgesic effects on animal models of inflammatory and neuropathic pain[1][2].

IC 50

Nav1.7: 26 nM (IC₅₀); Nav1.3: 338 nM (IC₅₀); Nav1.4: 400 nM (IC₅₀); Nav1.2: 150 nM (IC₅₀)

References

[1] Xiao Y, et, al. Tarantula huwentoxin-IV inhibits neuronal sodium channels by binding to receptor site 4 and trapping the domain ii voltage sensor in the closed configuration. J Biol Chem. 2008 Oct 3;283(40):27300-13. DOI:10.1074/jbc.M708447200
[2] Liu Y, et, al. Analgesic effects of Huwentoxin-IV on animal models of inflammatory and neuropathic pain. Protein Pept Lett. 2014; 21(2): 153-8. DOI:10.2174/09298665113206660119

HUWENTOXIN IV Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

HUWENTOXIN IV Suppliers

China 38 Japan 1 United Kingdom 1 United States 5 USA 1 Global 46

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Zhejiang J&C Biological Technology Co.,Limited

Tel: +1-2135480471
Email: sales@sarms4muscle.com
Country: China
ProdList: 10473
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
Advantage: 58

Hefei KS-V Peptide Biotechnology Co., Ltd.

Tel: 0551-65120828 17368858770
Email: sales1@difficultpeptide.com
Country: China
ProdList: 118
Advantage: 58

Wuxi Helen Biotechnology Co., Ltd.,

Tel: 0510-85629785 18013409632
Fax: 0510-85625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 14081
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

526224-73-7, HUWENTOXIN IVRelated Search:

CALCICLUDINE ω-conotoxin CVIA Protoxin ll MARGATOXIN ODK2 KURTOXIN ODK2 analogues μ-conotoxin GlllA SHK TOXIN OMEGA-AGATOXIN IVA SSD609 mu-conotoxin PLTX-ll CALCISEPTINE ω-conotoxin MVllA Dendrotoxin-l ω-agatoxin IVB SNX-482

HUWENTOXIN IV

HUWENTOXIN IV USP/EP/BP

526224-73-7

C174H278N52O51S6