MARGATOXIN

Uses

Product Name: MARGATOXIN
CAS No.: 145808-47-5
Chemical Name: MARGATOXIN
Synonyms: MGTX;RMGTX;MARGATOXIN;RMARGATOXIN;MGTX (SCORPION);MARGATOXIN (MGTX);BARK SCORPION VENOM;MARGATOXIN (SCORPION);MARGATOXIN, RECOMBINANT;Margatoxin (0.1mg vial)
CBNumber: CB8739829
Molecular Formula: C178H286N52O50S7
Formula Weight: 4178.94884
MOL File: 145808-47-5.mol

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MARGATOXIN Property

storage temp.: -20°C
form: Powder
color: White to off-white
Water Solubility: Soluble to 0.50 mg/ml in water
Sequence: Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His (Disulfide bridge:Cys7-Cys29;Cys13-Cys34;Cys17-Cys36)

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Safety

Safety Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P321Specific treatment (see … on this label).

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: M8437
Product name: Margatoxin
Purity: ≥99%, recombinant, expressed in E. coli
Packaging: 10μg
Price: $214.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: M8278
Product name: Margatoxin
Packaging: 0.1mg
Price: $910
Updated: 2025/07/31

Tocris

Product number: 3563
Product name: Margatoxin
Packaging: 100U
Price: $447
Updated: 2021/12/16

Usbiological

Product number: 255753
Product name: Margatoxin
Packaging: 100ug
Price: $819
Updated: 2021/12/16

TRC

Product number: M197308
Product name: Margatoxin,Recombinant
Packaging: 10μg
Price: $125
Updated: 2021/12/16

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MARGATOXIN Chemical Properties,Usage,Production

Uses

Margatoxin is a highly pure, synthetic, and biologically active peptide toxin.

Uses

Margatoxin, Recombinant is a specific blocker of Kv1.3, Kv1.6 channels.

Uses

Biochemical probe.

Biochem/physiol Actions

Margatoxin is an α-KTx toxin, which is majorly used in ion channel research. It is a 39-amino acid peptide, which is a specific K(V)1.3 channel voltage-dependent K+ channel blocker. Margatoxin is an immunosuppressant that is isolated from the venom of the scorpion Centruroides margaritatus.

in vivo

Margatoxin (i.p.; 1 pmol/g) significantly decreases thiogycollate-induced leukocyte transmigration in the peritoneal cavity in 12-week-old C57BL6/J mice^[2].

storage

-20°C

MARGATOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

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MARGATOXIN Suppliers

China 55 France 1 Germany 1 Japan 2 Switzerland 2 United Kingdom 3 United States 11 Global 75

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

145808-47-5, MARGATOXINRelated Search:

TERT-BUTYL ISOCYANIDE DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) Tris(2,4-pentanedionato)chroMiuM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) Tosylmethyl isocyanide SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE N-BUTYLISOCYANIDE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Ferric acetylacetonate Aluminum acetylacetonate Cupric acetylacetonate METHYL ISOCYANOACETATE Benzyl isocyanide Ethyl isocyanoacetate PHENYLSELENOL COBALT(II) ACETYLACETONATE

MARGATOXIN

MARGATOXIN, RECOMBINANT

MARGATOXIN (SCORPION)

RMGTX

RMARGATOXIN

SCORPION VENOM CENTRUROIDES SCULPTURATUS

MGTX

MGTX (SCORPION)

H-THR-ILE-ILE-ASN-VAL-LYS-CYS-THR-SER-PRO-LYS-GLN-CYS-LEU-PRO-PRO-CYS-LYS-ALA-GLN-PHE-GLY-GLN-SER-ALA-GLY-ALA-LYS-CYS-MET-ASN-GLY-LYS-CYS-LYS-CYS-TYR PRO-HIS-OH

BARK SCORPION VENOM

THR-ILE-ILE-ASN-VAL-LYS-CYS-THR-SER-PRO-LYS-GLN-CYS-LEU-PRO-PRO-CYS-LYS-ALA-GLN-PHE-GLY-GLN-SER-ALA-GLY-ALA-LYS-CYS-MET-ASN-GLY-LYS-CYS-LYS-CYS-TYR-PRO-HIS

MARGATOXIN >97%PURITY \ SPECIFIC K(V)1.3 CHANNEL K+CHANNEL BLOCKER

MARGATOXIN SCORPION, CENTRUROIDES*MARGAR ITATUS

margatoxin from centruroides margaritatus (scorpion)

MARGATOXIN (MGTX)

H-Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His-OH

Margatoxin (0.1mg vial)

145808-47-5

C178H286N52O50S7

Cell Biology

Cell Signaling and Neuroscience

BioChemical

Ion Channels

Monovalent Ion Channels

Voltage-gated Ion Channels

Potassium Channel Modulators