ChemicalBook > CAS DataBase List > CP-424,174

CP-424,174

Product Name
CP-424,174
CAS No.
210825-31-3
Chemical Name
CP-424,174
Synonyms
CP-424,174;CP-424,174 >=98% (HPLC);N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide;CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR);N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide;Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
CBNumber
CB54741315
Molecular Formula
C22H29ClN2O4S
Formula Weight
452.99
MOL File
210825-31-3.mol
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CP-424,174 Property

Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
form 
powder
pka
4.67±0.10(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PZ0347
Product name
CP-424,174
Purity
≥98% (HPLC)
Packaging
5mg
Price
$114
Updated
2024/03/01
Sigma-Aldrich
Product number
PZ0347
Product name
CP-424,174
Purity
≥98% (HPLC)
Packaging
25mg
Price
$464
Updated
2024/03/01
Tocris
Product number
6107
Product name
CP424174
Purity
≥98%(HPLC)
Packaging
10
Price
$117
Updated
2021/12/16
Tocris
Product number
6107
Product name
CP424174
Purity
≥98%(HPLC)
Packaging
50
Price
$393
Updated
2021/12/16
TRC
Product number
C781493
Product name
CP424174
Packaging
1mg
Price
$75
Updated
2021/12/16
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CP-424,174 Chemical Properties,Usage,Production

Biochem/physiol Actions

CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.

CP-424,174 Preparation Products And Raw materials

Raw materials

Preparation Products

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CP-424,174 Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

210825-31-3, CP-424,174Related Search:


  • CP-424,174
  • N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide
  • Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-
  • CP-424,174 >=98% (HPLC)
  • N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide
  • CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR)
  • 210825-31-3