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MM 07

Product Name
MM 07
CAS No.
1876450-21-3
Chemical Name
MM 07
Synonyms
MM 07;MM 07 TFA;CRPRLCHKGPMPF(Modification: Disulfide bridge: 1-6)
CBNumber
CB54797084
Molecular Formula
C67H106N22O14S3
Formula Weight
1539.91
MOL File
1876450-21-3.mol
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MM 07 Property

Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20° C
pka
3.56±0.10(Predicted)
form 
Solid
color 
White to off-white
Water Solubility 
Souble in water
Sequence
Cys-Arg-Pro-Arg-Leu-Cys-His-Lys-Gly-Pro-Met-Pro-Phe (Disulfide bridge:Cys1-Cys6)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
7053
Product name
MM07
Packaging
1
Price
$145
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573206
Product name
MM 07
Packaging
100mg
Price
$1802
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573206
Product name
MM 07
Packaging
250mg
Price
$3580.2
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573206
Product name
MM 07
Packaging
1g
Price
$7136.6
Updated
2021/12/16
DC Chemicals
Product number
DC12083
Product name
MM07
Purity
>98%
Packaging
100mg
Price
$950
Updated
2021/12/16
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MM 07 Chemical Properties,Usage,Production

Uses

MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart.

in vivo

MM 07 causes a dose-dependent increase in cardiac output, and although there is a decrease in vascular resistance, this is without corresponding effects on BP. Administration of SNAP produces a profound fall in BP in both [Pyr1]apelin-13 and MM 07-treated groups; however, although cardiac output is significantly increased in response to SNAP in the MM 07 group, it is significantly reduced in the [Pyr1]apelin-13 group. Neither peptide causes a significant change in heart rate, respiratory rate, or temperature. Both [Pyr1]apelin 13 and MM 07 increases peak velocity above basal levels[1].

References

[1] Brame AL, et al. Design, characterization, and first-in-human study of the vascular actions of a novel biased apelin receptor agonist. Hypertension. 2015 Apr;65(4):834-40. DOI:10.1161/HYPERTENSIONAHA.114.05099

MM 07 Preparation Products And Raw materials

Raw materials

Preparation Products

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MM 07 Suppliers

Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
Email
Caroline@youngshechem.com
Country
China
ProdList
4802
Advantage
58
Hangzhou Peptidego Biotech Co.,Ltd.
Tel
0571-87213919
Email
Eric@peptidego.com
Country
China
ProdList
7408
Advantage
58
Beijing xinyanhui pharmaceutical research and development co., LTD
Tel
13969155946
Email
1461866103@qq.com
Country
China
ProdList
16111
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11218
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58
Shanghai hongqu biomedical technology co. LTD
Tel
88888888888
Email
hongquchem@qq.com
Country
China
ProdList
5132
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58
Hangzhou Go Top Peptide Biotech
Tel
15397062932
Email
sales1@gotopbio.com
Country
China
ProdList
2923
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
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58
Kaifeng Mingren Pharmaceutical Co.,LTD
Tel
0371-65741762
Fax
QQ:2860768577
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sales@hasunny.com
Country
China
ProdList
2380
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Shaoxing Junyu Biotechnology Co., LTD
Tel
0571-0571-88211921 19105816207
Email
sales4@gotopbio.com
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China
ProdList
5144
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Hangzhou Sinoda Pharmaceutical Technology Co. LTD
Tel
0571-87213919 17306812703
Email
3007955328@qq.com
Country
China
ProdList
6979
Advantage
58

1876450-21-3, MM 07Related Search:


  • MM 07
  • CRPRLCHKGPMPF(Modification: Disulfide bridge: 1-6)
  • MM 07 TFA
  • 1876450-21-3