Indeloxazine hydrochloride

Product Name: Indeloxazine hydrochloride
CAS No.: 65043-22-3
Chemical Name: Indeloxazine hydrochloride
Synonyms: Noin;Elen;CI 874;CI874l;CI-874l;YM 08054;YM 08054-1;Indeloxazine HCl;Indeloxazine hydrochloride;Indeloxadine hydrochloride
CBNumber: CB5481835
Molecular Formula: C14H18ClNO2
Formula Weight: 267.75
MOL File: 65043-22-3.mol

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Indeloxazine hydrochloride Property

Melting point:: 169-170°; mp 155-156°
storage temp.: Sealed in dry,Room Temperature

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Safety

RIDADR: 3249
HazardClass: 6.1(b)
PackingGroup: III
Toxicity: LD50 in mice (mg/kg): 47 i.v. (Tachikawa)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0002992
Product name: INDELOXAZINE HYDROCHLORIDE
Purity: 95.00%
Packaging: 100MG
Price: $577.5
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 35515
Product name: 2-(((1H-Inden-7-yl)oxy)methyl)morpholineHCl
Purity: 95+%
Packaging: 1g
Price: $1280
Updated: 2021/12/16

Crysdot

Product number: CD33000169
Product name: IndeloxazineHydrochloride
Purity: 95+%
Packaging: 1g
Price: $772
Updated: 2021/12/16

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Indeloxazine hydrochloride Chemical Properties,Usage,Production

Description

Indeloxazine hydrochloride is a nootropic indicated for the treatment of senile dementia. In animal models indeloxazine reportedly enhances brain energy metabolism and monoamine content; its claimed protective effect on ischemia-induced amnesia is supported by the prolonged step-through latency in passive avoidance tests.

Chemical Properties

Polycrystalline compounds: pale yellow needle-like (needles) crystals from methanol, melting point 169-170 ℃: colorless needle-like (acicular) crystals from acetone, melting point 155-156 ℃. Acute toxicity LD50 mice (mg/kg): 47 IV. (+)-configuration: crystallized from ethanol, melting point 112~113°C. [α]D21+4.9° (C=5, methanol). (-)-configuration: crystallized from isopropanol, melting point 142~142.5°C. [α]D20-4.9° (C=5, methanol).

Originator

Yamanouchi (Japan)

Uses

Antidepressant.

brand name

Elen

Metabolic pathway

After oral administration of indeloxazine hydrochloride to rats, two conjugates, which are labile to a- glucosidase hydrolysis but refractory to b-glucosidase, are isolated from the urine and identified as a-D- glucopyranosides of trans-4-(2-morpholinylmethoxy)- 1,2-indandiol and trans-6-[[(1,2-dihydroxy-4- indanyl)oxy]-methyl]-3-morpholinone.

Indeloxazine hydrochloride Preparation Products And Raw materials

Raw materials

Indene Expoxide 2-AMINOETHYL HYDROGEN SULFATE Isopropyl alcohol Chloro propylene oxide Magnesium sulfate

Preparation Products

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Indeloxazine hydrochloride Suppliers

China 21 China Hong Kong 1 Europe 2 India 1 United Kingdom 2 United States 8 USA 1 Global 36

Shanghai Boyle Chemical Co., Ltd.

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Chembest Research Laboratories Limited

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Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.

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Candia Thamtech Company Limited

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Shanghai Synmedia Chemical Co., Ltd.

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Chizhou Kailong Import and Export Trade Co., Ltd.

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Amadis Chemical Company Limited

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Hefei TNJ Chemical Industry Co.,Ltd.

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Shaanxi Dideu Medichem Co. Ltd

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CONIER CHEM AND PHARMA LIMITED

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TargetMol Chemicals Inc.

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Debye Scientific Corporation

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Lanospharma Laboratories Co.,Ltd

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65043-22-3, Indeloxazine hydrochlorideRelated Search:

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MORPHOLINE, 2-[(1H-INDEN-7-YLOXY)METHYL]-, HYDROCHLORIDE

Indeloxazine hydrochloride

CI 874

Elen

Noin

YM 08054

YM 08054-1

(±)-2-[(1H-Inden-7-yloxy)methyl]morpholine hydrochloride

Indeloxadine hydrochloride

Morpholine,2-[(1H-inden-7-yloxy)Methyl]-, hydrochloride (1:1)

Indeloxazine Hydrochloride: Indeloxazine HCl

Indeloxazine HCl

2-(3H-Inden-4-yloxymethyl)morpholine hydrochloride

Indeloxazine hydrochloride USP/EP/BP

CI874l

CI-874l

65043-22-3

C14H17N2OHCl