ChemicalBook > CAS DataBase List > Triethyl acetyl citrate

Triethyl acetyl citrate

Product Name
Triethyl acetyl citrate
CAS No.
77-89-4
Chemical Name
Triethyl acetyl citrate
Synonyms
ACETYL TRIETHYL CITRATE;ATEC;O-AcetyL;triethyl 2-acetoxypropane-1,2,3-tricarboxylate;Uniplex 82;Triethyl O;citroflexa2;Citroflex A 2;Trithylcitratc;ethyl acetylcitrate
CBNumber
CB5483819
Molecular Formula
C14H22O8
Formula Weight
318.32
MOL File
77-89-4.mol
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Triethyl acetyl citrate Property

Melting point:
-42°C
Boiling point:
228-229 °C/100 mmHg (lit.)
Density 
1.136 g/mL at 25 °C (lit.)
Pour Point 
-42
refractive index 
n20/D 1.439(lit.)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,Room Temperature
solubility 
Soluble 1 in 140 of water; miscible with acetone, ethanol, and propan-2-ol.
form 
Liquid
color 
Colourless
Odor
odorless
BRN 
1804947
LogP
2.170 (est)
CAS DataBase Reference
77-89-4(CAS DataBase Reference)
NIST Chemistry Reference
1,2,3-Propanetricarboxylic acid, 2-acetoxy-, triethyl ester(77-89-4)
EPA Substance Registry System
1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester (77-89-4)
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Safety

Safety Statements 
23-24/25
WGK Germany 
1
RTECS 
GE8225000
TSCA 
TSCA listed
HS Code 
2918150000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
388351
Product name
Triethyl 2-acetylcitrate
Purity
99%
Packaging
500ml
Price
$61.8
Updated
2024/03/01
Sigma-Aldrich
Product number
1009923
Product name
Acetyltriethyl citrate
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
500mg
Price
$450
Updated
2022/05/15
TCI Chemical
Product number
A0086
Product name
Triethyl O-Acetylcitrate
Purity
>97.0%(GC)
Packaging
25g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
A0086
Product name
Triethyl O-Acetylcitrate
Purity
>97.0%(GC)
Packaging
500g
Price
$68
Updated
2024/03/01
scipoly
Product number
P-108
Product name
Acetyl triethyl citrate
Packaging
100g
Price
$14
Updated
2024/07/03
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Triethyl acetyl citrate Chemical Properties,Usage,Production

Chemical Properties

Acetyltriethyl citrate occurs as a clear, odorless, practically colorless oily liquid.

Uses

ATEC is produced by the reaction of citric acid triethyl ester with acetic acid anhydride. It is used as a solvent plasticizer for cellulose nitrate and cellulose acetate.

Uses

Triethyl O-Acetylcitrate is used in the preparation of poly(lactic) acid biodegradable and flexible films, acting as a plasticizer. Also used in the synthesis of control-release capsules containing polymeric coatings.

Definition

Aqueous-based pharmaceutical coat- ings.

Production Methods

Acetyltriethyl citrate is prepared by the esterification of citric acid with ethanol followed by acylation with acetic anhydride.

General Description

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Triethyl 2-acetylcitrate is widely used in hydrophilic adhesives for medications and in biodegradable composition for papermaking and nonwoven production.

Pharmaceutical Applications

Acetyltriethyl citrate is used to plasticize polymers in formulated pharmaceutical coatings. The coating applications include capsules, tablets, beads and granules for taste masking, immediate release, sustained-release and enteric formulations. It is also used in diffusion-controlled release drug delivery systems.

Safety

Acetyltriethyl citrate is used in oral pharmaceutical formulations and is generally regarded as a nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.
LD50 (cat, oral): 8.5 g/kg
LD50 (mouse, IP): 1.15 g/kg
LD50 (rat, oral): 7 g/kg

storage

Acetyltriethyl citrate should be stored in dry, closed containers at temperatures not exceeding 388℃. When stored in accordance with these conditions, acetyltriethyl citrate is a stable product.

Incompatibilities

Acetyltriethyl citrate is incompatible with strong alkalis and oxidizing materials.

Regulatory Status

Approved in the USA for direct food contact in food films.

Triethyl acetyl citrate Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Triethyl acetyl citrate manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Triethyl acetyl citrate 77-89-4
Price
US $100.00/kg
Min. Order
1kg
Purity
98
Supply Ability
4000
Release date
2024-04-25
Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Acetyl Triethyl Citrate 77-89-4
Price
US $200.00-95.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-25
Hebei Weibang Biotechnology Co., Ltd
Product
Triethyl acetyl citrate 77-89-4
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-30

77-89-4, Triethyl acetyl citrate Related Search:

Triethyl methanetricarboxylate Calcium citrate Methyl acrylate Sodium citrate Triethyl citrate Acetyl tributyl citrate Diethyl phthalate Mosapride citrate Triethyl phosphite Ethyl 2,4-dioxovalerate 2-[5-(4-Chlorophenyl)pentyl]oxirane-2-carboxylic acid Ammonium citrate tribasic Triethyl phosphate Triethyl phosphonoacetate Sildenafil citrate Zinc citrate Tributyl citrate Tris(trimethylsilyl)phosphate

  • 1,2,3-Propanetricarboxylic acid, 2-(acetyloxy)-, triethyl ester
  • 1,2,3-Propanetricarboxylicacid,2-(acetyloxy)-,triethylester
  • 2,3-propanetricarboxylicacid,2-(acetyloxy)-triethylester
  • ATEC
  • Citric acid, acetyl triethyl ester
  • Citric acid, triethyl ester, acetate
  • citricacid,acetyltriethylester
  • citricacid,triethylester,acetate
  • Citroflex A 2
  • citroflexa2
  • o-Acetyl-triethylcitrate
  • ACETYL TRIETHYL CITRATE
  • 2-(Acetyloxy)-1,2,3-propanetricarboxylic acid triethyl ester
  • O-ACETYLCITRIC ACID TRIETHYL ESTER
  • triethyl acetyl citrate
  • TRIETHYL O-ACETYLCITRATE
  • Tricarballylic acid, beta-acetoxytributyl ester
  • tricarballylicacid,beta-acetoxytributylester
  • Triethyl 2-(acetyloxy)-1,2,3-propanetricarboxylate
  • Triethyl 2-acetoxy-1,2,3-propanetricarboxylate
  • Triethyl citrate acetate
  • triethylcitrate,acetate
  • Triethylester kyseliny acetylcitronove
  • triethylesterkyselinyacetylcitronove
  • Trithylcitratc
  • Uniplex 82
  • Triethyl-O-acetylcitrat
  • Triethyl 2-acetylcitrate
  • ethyl acetylcitrate
  • triethyl acetocitrate
  • 1,2,3-Triethyl 2-acetyloxypropane-1,2,3-tricarboxylate
  • 2-Acetoxy-1,2,3-propanetricarboxylic acid triethyl ester
  • 2-Acetoxypropane-1,2,3-tricarboxylic acid triethyl ester
  • Acetyl triethyl citrate 10g [77-89-4]
  • Triethyl 2-acetylcitrate,Acetyl triethyl citrate
  • Acetyltriethyl Citrate (500 mg)
  • triethyl 2-acetoxypropane-1,2,3-tricarboxylate
  • Triethyl 2-acetylcitr
  • 1,2,3-Propanetricarboxylicacid, 2-(acetyloxy)-, 1,2,3-triethyl ester
  • Triethyl 2-acetylcitrate 99%
  • O-AcetyL
  • Triethyl O-Acetylcitrate &gt
  • Triethyl O
  • Triethyl acetyl citrate ISO 9001：2015 REACH
  • Methyl Iodide (lodomethane)
  • Acetyltriethyl Citrate (100 mg)
  • 77-89-4
  • 77-88-4
  • CH3COOCCOOCH2CH3CH2COOCH2CH32
  • Hydroxycarboxylic Acid Esters (Plasticizer)
  • Plasticizer
  • Esters
  • Organic Building Blocks
  • Building Blocks
  • Carbonyl Compounds
  • C12 to C63
  • Hydroxycarboxylic Acid Esters (Plasticizer)
  • Functional Materials