U-63557A

Product Name: U-63557A
CAS No.: 85666-17-7
Chemical Name: U-63557A
Synonyms: U-63557A;C15H11NO3.Na;furegralate sodium;SODIUM FUREGRELATE;FUREGRELATE SODIUM;FUREGRELATE SODIUM SALT;Furegrelate Sodium (U-63557A);Furegrelate sodium, 10 mM in DMSO;Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate;5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
CBNumber: CB5484371
Molecular Formula: C15H12NNaO3
Formula Weight: 277.25
MOL File: 85666-17-7.mol

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U-63557A Property

storage temp.: −20°C
solubility: DMF: >25 mg/ml; DMSO: >21 mg/ml; Ethanol: >14.5 mg/ml; PBS pH 7.2: >16.5 mg/ml
form: White to off-white crystalline solid.
color: White to light yellow
Water Solubility: Soluble in water at approximately 15mg/ml

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 70540
Product name: Furegrelate (sodium salt)
Purity: ≥99%
Packaging: 5mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 70540
Product name: Furegrelate (sodium salt)
Purity: ≥99%
Packaging: 10mg
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 70540
Product name: Furegrelate (sodium salt)
Purity: ≥99%
Packaging: 50mg
Price: $437
Updated: 2024/03/01

TRC

Product number: F864133
Product name: FuregrelateSodium(U-63557A)
Packaging: 25mg
Price: $175
Updated: 2021/12/16

Usbiological

Product number: 450991
Product name: Furegrelate Sodium
Packaging: 10mg
Price: $360
Updated: 2021/12/16

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U-63557A Chemical Properties,Usage,Production

Uses

Inhibitor (thromboxane synthetase).

Uses

Furegrelate Sodium (U-63557A) is a selective and potent thromboxane A2 synthase (TXA2R) inhibitor in platelets.

in vivo

Furegrelate Sodium (1-5 mg/kg; po) prevents blockage of the coronary artery^[1].
Furegrelate Sodium (0.1-5 mg/kg; i.v.) prevents the blockage of stenosed coronary arteries caused platelet aggregation^[1].
Furegrelate Sodium blunts the development of hypoxia-induced pulmonary arterial hypertension (PAH) in an established neonatal piglet model primarily by preserving the structural integrity of the pulmonary vasculature^[2].
Furegrelate has a long half-life compared to several other drugs used to treat PAH, including nitric oxide and prostagcyclin analogues; And Furegrelate is highly specific to the target enzyme^[2].

Animal Model:	Mongrel dogs (19-30 kg)^[1]
Dosage:	1-5 mg/kg
Administration:	Oral (via a gastric tube)
Result:	Prevented blockage of the coronary artery.

U-63557A Preparation Products And Raw materials

Raw materials

Preparation Products

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U-63557A Suppliers

China 25 Germany 1 India 1 Switzerland 2 United Kingdom 1 United States 12 Global 42

Shanghai RenYue Chemical Technology Co., Ltd.

Tel: 021-62219190; 18321139117
Email: 316441092@qq.com
Country: China
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BOC Sciences

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Email: info@bocsci.com
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Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
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Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
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Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
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Email: amber@biochempartner.com
Country: China
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
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Shanghai hongqu biomedical technology co. LTD

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Country: China
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MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
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85666-17-7, U-63557ARelated Search:

ASISCHEM C63557 FUREGRELATE Benzofuran-2-carboxylic acid 2-Benzofurancarboxaldehyde 5-methylbenzofuran Furfuryl alcohol 2-Furoic acid 3-BENZYLPYRIDINE 5-METHYL-BENZOFURAN-2-CARBOXYLIC ACID 1-BENZOFURAN-2-YLMETHANOL U-63557A

SODIUM FUREGRELATE

U-63557A

FUREGRELATE SODIUM

FUREGRELATE SODIUM SALT

5-(3-PYRIDINYLMETHYL)-2-BENZOFURANCARBOXYLIC ACID, SODIUM SALT

5-[3,PYRIDINYLMETHYL]BENZO-FURAN-CARBOXYLIC ACID SODIUM SALT

furegralate sodium

5-(3-Pyridinylmethyl)benzofurancarboxylic acid sodium-potassium salt

5-(3-Pyridylmethyl)benzofuran-2-carboxylic acid sodium salt

2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-, sodium salt

5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium

Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate

Furegrelate Sodium (U-63557A)

sodium:5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylate

arteries,hypertension,available,Furegrelate,inhibit,orally,antiplatelet,platelet,arterial,human,stenosed,Inhibitor,pulmonary,Furegrelate sodium,coronary

Furegrelate sodium, 10 mM in DMSO

C15H11NO3.Na

85666-17-7

C15H10NO3Na

C15H10NNaO3