U-63557A

Product Name: U-63557A
CAS No.: 85666-17-7
Chemical Name: U-63557A
Synonyms: U-63557A;C15H11NO3.Na;furegralate sodium;SODIUM FUREGRELATE;FUREGRELATE SODIUM;FUREGRELATE SODIUM SALT;Furegrelate Sodium (U-63557A);Furegrelate sodium, 10 mM in DMSO;Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate;5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
CBNumber: CB5484371
Molecular Formula: C15H12NNaO3
Formula Weight: 277.25
MOL File: 85666-17-7.mol

More

Less

U-63557A Property

storage temp.: −20°C
solubility: DMF: >25 mg/ml; DMSO: >21 mg/ml; Ethanol: >14.5 mg/ml; PBS pH 7.2: >16.5 mg/ml
form: White to off-white crystalline solid.
color: White to light yellow
Water Solubility: Soluble in water at approximately 15mg/ml

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 70540
Product name: Furegrelate (sodium salt)
Purity: ≥99%
Packaging: 5mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 70540
Product name: Furegrelate (sodium salt)
Purity: ≥99%
Packaging: 10mg
Price: $107
Updated: 2024/03/01

Cayman Chemical

Product number: 70540
Product name: Furegrelate (sodium salt)
Purity: ≥99%
Packaging: 50mg
Price: $437
Updated: 2024/03/01

Usbiological

Product number: 450991
Product name: Furegrelate Sodium
Packaging: 10mg
Price: $360
Updated: 2021/12/16

TRC

Product number: F864133
Product name: FuregrelateSodium(U-63557A)
Packaging: 25mg
Price: $175
Updated: 2021/12/16

More

Less

U-63557A Chemical Properties,Usage,Production

Uses

Inhibitor (thromboxane synthetase).

Uses

Furegrelate Sodium (U-63557A) is a selective and potent thromboxane A2 synthase (TXA2R) inhibitor in platelets.

in vivo

Furegrelate Sodium (1-5 mg/kg; po) prevents blockage of the coronary artery^[1].
Furegrelate Sodium (0.1-5 mg/kg; i.v.) prevents the blockage of stenosed coronary arteries caused platelet aggregation^[1].
Furegrelate Sodium blunts the development of hypoxia-induced pulmonary arterial hypertension (PAH) in an established neonatal piglet model primarily by preserving the structural integrity of the pulmonary vasculature^[2].
Furegrelate has a long half-life compared to several other drugs used to treat PAH, including nitric oxide and prostagcyclin analogues; And Furegrelate is highly specific to the target enzyme^[2].

Animal Model:	Mongrel dogs (19-30 kg)^[1]
Dosage:	1-5 mg/kg
Administration:	Oral (via a gastric tube)
Result:	Prevented blockage of the coronary artery.

U-63557A Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

U-63557A Suppliers

China 25 Germany 1 India 1 Switzerland 2 United Kingdom 1 United States 12 Global 42

Shanghai RenYue Chemical Technology Co., Ltd.

Tel: 021-62219190; 18321139117
Email: 316441092@qq.com
Country: China
ProdList: 2912
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shanghai Han-Xiang Chemical Co., Ltd.

Tel: 15971444841
Fax: 18327183813
Email: amber@biochempartner.com
Country: China
ProdList: 3061
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

MedBioPharmaceutical Technology Inc

Tel: 021-69568360 18916172912
Email: order@med-bio.cn
Country: China
ProdList: 8140
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Shanghai Universal Biotech Co.,Ltd

Tel: 15921930842 15921930842
Email: yh-wang@univ-bio.com
Country: China
ProdList: 25004
Advantage: 58

Kaifeng Mingren Pharmaceutical Co.,LTD

Tel: 0371-65741762
Fax: QQ：2860768577
Email: sales@hasunny.com
Country: China
ProdList: 2380
Advantage: 58

TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
Advantage: 58

Nantong QuanYi Biotechnology Co., Ltd

Tel: 0513-66337626 18051384581
Email: sales@chemhifuture.com
Country: China
ProdList: 5929
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: cindy.huang@synzest.com
Country: China
ProdList: 12000
Advantage: 58

Shaanxi Istare Biotechnology Co., Ltd.

Tel: 18682931470; 18682931470
Email: 2142355700@qq.com
Country: China
ProdList: 4723
Advantage: 58

Jiangsu Aikon Biopharmaceutical R&D Co.,Ltd

Tel: 025-58851090 17714375163
Email: 2881759498@qq.com
Country: China
ProdList: 13011
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 13308200041
Email: 2851167782@qq.com
Country: China
ProdList: 11146
Advantage: 58

Sangon Biotech (Shanghai) Co.,Ltd.

Tel: 400-821-026
Email: Sales@sangon.com
Country: China
ProdList: 6710
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Lucheng (Shenzhen) Technology Co., Ltd.

Tel: 13128698830
Country: CHINA
ProdList: 181
Advantage: 58

Neobioscience Co., Ltd.

Tel: --
Fax: --
Email: info@neobioscience.com
Country: CHINA
ProdList: 6207
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Proteintech China

Tel: --
Fax: --
Email: Proteintech-CN@ptglab.com
Country: CHINA
ProdList: 6290
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Advanced Technology & Industrial Co., Ltd.

Tel: --
Fax: --
Email: sales@advtechind.com
Country: China
ProdList: 6523
Advantage: 75

85666-17-7, U-63557ARelated Search:

ASISCHEM C63557 FUREGRELATE Benzofuran-2-carboxylic acid 2-Benzofurancarboxaldehyde 5-methylbenzofuran Furfuryl alcohol 2-Furoic acid 3-BENZYLPYRIDINE 5-METHYL-BENZOFURAN-2-CARBOXYLIC ACID 1-BENZOFURAN-2-YLMETHANOL U-63557A

SODIUM FUREGRELATE

U-63557A

FUREGRELATE SODIUM

FUREGRELATE SODIUM SALT

5-(3-PYRIDINYLMETHYL)-2-BENZOFURANCARBOXYLIC ACID, SODIUM SALT

5-[3,PYRIDINYLMETHYL]BENZO-FURAN-CARBOXYLIC ACID SODIUM SALT

furegralate sodium

5-(3-Pyridinylmethyl)benzofurancarboxylic acid sodium-potassium salt

5-(3-Pyridylmethyl)benzofuran-2-carboxylic acid sodium salt

2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-, sodium salt

5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium

Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate

Furegrelate Sodium (U-63557A)

sodium:5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylate

arteries,hypertension,available,Furegrelate,inhibit,orally,antiplatelet,platelet,arterial,human,stenosed,Inhibitor,pulmonary,Furegrelate sodium,coronary

Furegrelate sodium, 10 mM in DMSO

C15H11NO3.Na

85666-17-7

C15H10NO3Na

C15H10NNaO3