ChemicalBook > CAS DataBase List > U-63557A

U-63557A

Product Name
U-63557A
CAS No.
85666-17-7
Chemical Name
U-63557A
Synonyms
U-63557A;C15H11NO3.Na;furegralate sodium;SODIUM FUREGRELATE;FUREGRELATE SODIUM;FUREGRELATE SODIUM SALT;Furegrelate Sodium (U-63557A);Furegrelate sodium, 10 mM in DMSO;Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate;5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
CBNumber
CB5484371
Molecular Formula
C15H12NNaO3
Formula Weight
277.25
MOL File
85666-17-7.mol
More
Less

U-63557A Property

storage temp. 
−20°C
solubility 
DMF: >25 mg/ml; DMSO: >21 mg/ml; Ethanol: >14.5 mg/ml; PBS pH 7.2: >16.5 mg/ml
form 
White to off-white crystalline solid.
color 
White to light yellow
Water Solubility 
Soluble in water at approximately 15mg/ml
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
70540
Product name
Furegrelate (sodium salt)
Purity
≥99%
Packaging
5mg
Price
$57
Updated
2024/03/01
Cayman Chemical
Product number
70540
Product name
Furegrelate (sodium salt)
Purity
≥99%
Packaging
10mg
Price
$107
Updated
2024/03/01
Cayman Chemical
Product number
70540
Product name
Furegrelate (sodium salt)
Purity
≥99%
Packaging
50mg
Price
$437
Updated
2024/03/01
Usbiological
Product number
450991
Product name
Furegrelate Sodium
Packaging
10mg
Price
$360
Updated
2021/12/16
TRC
Product number
F864133
Product name
FuregrelateSodium(U-63557A)
Packaging
25mg
Price
$175
Updated
2021/12/16
More
Less

U-63557A Chemical Properties,Usage,Production

Uses

Inhibitor (thromboxane synthetase).

Uses

Furegrelate Sodium (U-63557A) is a selective and potent thromboxane A2 synthase (TXA2R) inhibitor in platelets.

in vivo

Furegrelate Sodium (1-5 mg/kg; po) prevents blockage of the coronary artery[1].
Furegrelate Sodium (0.1-5 mg/kg; i.v.) prevents the blockage of stenosed coronary arteries caused platelet aggregation[1].
Furegrelate Sodium blunts the development of hypoxia-induced pulmonary arterial hypertension (PAH) in an established neonatal piglet model primarily by preserving the structural integrity of the pulmonary vasculature[2].
Furegrelate has a long half-life compared to several other drugs used to treat PAH, including nitric oxide and prostagcyclin analogues; And Furegrelate is highly specific to the target enzyme[2].

Animal Model:Mongrel dogs (19-30 kg)[1]
Dosage:1-5 mg/kg
Administration:Oral (via a gastric tube)
Result:Prevented blockage of the coronary artery.

U-63557A Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

U-63557A Suppliers

China 25 Germany 1 India 1 Switzerland 2 United Kingdom 1 United States 12 Global 42
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Alexis Corporation
Tel
--
Fax
--
Email
alexis-ch@alexis-corp.ch
Country
Switzerland
ProdList
3599
Advantage
74

85666-17-7, U-63557ARelated Search:

ASISCHEM C63557 FUREGRELATE Benzofuran-2-carboxylic acid 2-Benzofurancarboxaldehyde 5-methylbenzofuran Furfuryl alcohol 2-Furoic acid 3-BENZYLPYRIDINE 5-METHYL-BENZOFURAN-2-CARBOXYLIC ACID 1-BENZOFURAN-2-YLMETHANOL U-63557A

  • SODIUM FUREGRELATE
  • U-63557A
  • FUREGRELATE SODIUM
  • FUREGRELATE SODIUM SALT
  • 5-(3-PYRIDINYLMETHYL)-2-BENZOFURANCARBOXYLIC ACID, SODIUM SALT
  • 5-[3,PYRIDINYLMETHYL]BENZO-FURAN-CARBOXYLIC ACID SODIUM SALT
  • furegralate sodium
  • 5-(3-Pyridinylmethyl)benzofurancarboxylic acid sodium-potassium salt
  • 5-(3-Pyridylmethyl)benzofuran-2-carboxylic acid sodium salt
  • 2-Benzofurancarboxylic acid, 5-(3-pyridinylmethyl)-, sodium salt
  • 5-(3'-Pyridinylmethyl)benzofuran-2-carboxylate sodium
  • Sodium 5-(3-pyridinylmethyl)-2-benzofurancarboxylate
  • Furegrelate Sodium (U-63557A)
  • sodium:5-(pyridin-3-ylmethyl)-1-benzofuran-2-carboxylate
  • arteries,hypertension,available,Furegrelate,inhibit,orally,antiplatelet,platelet,arterial,human,stenosed,Inhibitor,pulmonary,Furegrelate sodium,coronary
  • Furegrelate sodium, 10 mM in DMSO
  • C15H11NO3.Na
  • 85666-17-7
  • C15H10NO3Na
  • C15H10NNaO3