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1-ACETYLINDOLINE

Product Name
1-ACETYLINDOLINE
CAS No.
16078-30-1
Chemical Name
1-ACETYLINDOLINE
Synonyms
1-ACETYLINDOLINE;1-acetyl-indolin;N-ACETYL INDOLINE;Acetylindoline,N-;1-ACETYLINDOLINE 98+%;1-ACETYL-2,3-DIHYDROINDOLE;1-(indolin-1-yl)ethan-1-one;1-acetyl-2,3-dihydro-1h-indol;1-Acetyl-2,3-dihydro-1H-indole;1H-Indole, 1-acetyl-2,3-dihydro-
CBNumber
CB5487514
Molecular Formula
C10H11NO
Formula Weight
161.2
MOL File
16078-30-1.mol
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1-ACETYLINDOLINE Property

Melting point:
102-104 °C(lit.)
Boiling point:
125-130 °C(Press: 1 Torr)
Density 
1.144±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
1.13±0.20(Predicted)
Appearance
White to light brown Solid
InChI
1S/C10H11NO/c1-8(12)11-7-6-9-4-2-3-5-10(9)11/h2-5H,6-7H2,1H3
InChIKey
RNTCWULFNYNFGI-UHFFFAOYSA-N
SMILES
CC(=O)N1CCc2ccccc12
CAS DataBase Reference
16078-30-1(CAS DataBase Reference)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
NM1892500
HS Code 
2933998090
Storage Class
11 - Combustible Solids
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
379492
Product name
1-Acetylindoline
Purity
98%
Packaging
5g
Price
$43.9
Updated
2023/06/20
TCI Chemical
Product number
A3508
Product name
1-(Indolin-1-yl)ethan-1-one
Purity
min. 95.0 %
Packaging
5G
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
A3508
Product name
1-(Indolin-1-yl)ethan-1-one
Purity
min. 95.0 %
Packaging
25G
Price
$231
Updated
2025/07/31
TRC
Product number
D448340
Product name
1-(2,3-Dihydroindol-1-yl)ethanone
Packaging
25g
Price
$230
Updated
2021/12/16
AK Scientific
Product number
V3605
Product name
1-Acetylindoline
Packaging
5g
Price
$11
Updated
2021/12/16
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1-ACETYLINDOLINE Chemical Properties,Usage,Production

Uses

• ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5

Uses

1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone.

Uses

  • Reactant for preparation of triazolothiadiazepine dioxide derivatives
  • Reactant for preparation of halo-substituted aromatic amides
  • Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
  • Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
  • Reactant for regioselective ortho Suzuki-Miyaura coupling reaction

Synthesis Reference(s)

Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9
Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1

General Description

1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported.

1-ACETYLINDOLINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-ACETYLINDOLINE Suppliers

Belgium 1 China 151 Europe 3 France 1 Germany 4 India 5 Japan 1 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 15 United States 23 Global 209
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Beijing Ouhe Technology Co., Ltd
Tel
010-010-82967028 13522913783
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
11999
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9309
Advantage
66
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
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View Lastest Price from 1-ACETYLINDOLINE manufacturers

Career Henan Chemical Co
Product
1-ACETYLINDOLINE 16078-30-1
Price
US $1.00/KG
Min. Order
1KG
Purity
95-99%
Supply Ability
100kg/week
Release date
2019-08-05

16078-30-1, 1-ACETYLINDOLINERelated Search:

Indoline N-ACETYLINDOLE-3-CARBOXALDEHYDE 1-ACETYL-5-BROMOINDOLINE 1-ACETYL-5-AMINO-2,3-DIHYDRO-(1H)-INDOLE STRYCHNINE 10,11-Dimethoxystrychnine BRUCINE SULFATE Strychnine Nitrate 1-ACETYL-6-AMINOINDOLINE STRYCHNINE HYDROCHLORIDE 1-ACETYL-5-BROMO-7-NITROINDOLINE 1-ACETYLINDOLINE 1-ACETYL-5-NITROINDOLINE BRUCINE HYDROCHLORIDE 1-acetylindoline-2,3-dione Strychnine Sulfate STRYCHNINE-N-OXIDE 1-ACETYL-6-CHLOROINDOLINE

  • 1-acetyl-2,3-dihydro-1h-indol
  • 1-acetyl-indolin
  • 1-(2,3-DIHYDRO-1H-INDOL-1-YL)ETHAN-1-ONE
  • 1-(2,3-DIHYDRO-INDOL-1-YL)-ETHANONE
  • 1-ACETYL-2,3-DIHYDROINDOLE
  • 1-ACETYLINDOLINE
  • Acetylindoline,N-
  • 1H-Indole, 1-acetyl-2,3-dihydro- (9CI)
  • N-ACETYL INDOLINE
  • 1-ACETYLINDOLINE 98+%
  • 1H-Indole, 1-acetyl-2,3-dihydro-
  • 1-Acetyl-2,3-dihydro-1H-indole
  • Ethanone, 1-(2,3-dihydro-1H-indol-1-yl)-
  • 1-(indolin-1-yl)ethan-1-one
  • 16078-30-1
  • Indoles
  • Heterocyclic Building Blocks
  • Building Blocks
  • Building Blocks
  • C10
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Building Blocks
  • Heterocyclic Building Blocks
  • Indoles
  • Indoline & Oxindole
  • ACETYLGROUP
  • Indoles and derivatives