4-Hydroxy-6-(trifluoromethyl)pyrimidine

Product Name: 4-Hydroxy-6-(trifluoromethyl)pyrimidine
CAS No.: 1546-78-7
Chemical Name: 4-Hydroxy-6-(trifluoromethyl)pyrimidine
Synonyms: 6-TRIFLUOROMETHYL-4-PYRIMIDINOL;6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL;4-PYRIMIDINOL, 6-(TRIFLUOROMETHYL)-;6-Trifluoromethyl-4(1H)-pyrimidinone;6-TRIFLUOROMETHYL-4-PYRIMIDINOL 98+%;4-HYDROXY-6-TRIFLUOROMETHYLPYRIMIDINE;6-trifluoromethyl-4-hydroxypyrimidine;4-Hydroxy-6-(trifluormethyl)-pyrimidin;6-(trifluoromethyl)pyrimidin-4(3H)-one;6-(trifluoromethyl)-1H-pyrimidin-4-one
CBNumber: CB5488081
Molecular Formula: C5H3F3N2O
Formula Weight: 164.09
MOL File: 1546-78-7.mol

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4-Hydroxy-6-(trifluoromethyl)pyrimidine Property

Melting point:: 169-171 °C(lit.)
Boiling point:: 130.3±50.0 °C(Predicted)
Density: 1.55±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 6.41±0.40(Predicted)
form: Crystalline
color: White
Water Solubility: Solubility in methanol (almost transparency). Slightly soluble in water.
BRN: 145548
CAS DataBase Reference: 1546-78-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 385344
Product name: 4-Hydroxy-6-(trifluoromethyl)pyrimidine
Purity: 99%
Packaging: 1g
Price: $43.3
Updated: 2023/01/07

TCI Chemical

Product number: T1601
Product name: 6-Trifluoromethyl-4-pyrimidinol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $36
Updated: 2024/03/01

TCI Chemical

Product number: T1601
Product name: 6-Trifluoromethyl-4-pyrimidinol
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $129
Updated: 2024/03/01

Alfa Aesar

Product number: H64381
Product name: 4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%
Packaging: 1g
Price: $31.4
Updated: 2023/06/20

Alfa Aesar

Product number: H64381
Product name: 4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%
Packaging: 5g
Price: $141
Updated: 2023/06/20

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4-Hydroxy-6-(trifluoromethyl)pyrimidine Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

4-Hydroxy-6-(trifluoromethyl)pyrimidine (6-(Trifluoromethyl)-4-pyrimidinol) may be used in the synthesis of 10-[3-(6-trifluoromethyl-pyrimidin-4-yloxy)-propoxy]-(20S)-camptothecin.

Uses

4-Hydroxy-6-(trifluoromethyl)pyrimidine is used as building block in chemical synthesis. Attributes Development Product Contact

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 5744, 1958 DOI: 10.1021/ja01554a041

General Description

4-Hydroxy-6-(trifluoromethyl)pyrimidine, a pyrimidine derivative, is a heterocyclic building block.

4-Hydroxy-6-(trifluoromethyl)pyrimidine Preparation Products And Raw materials

Raw materials

Ethyl 4,4,4-trifluoroacetoacetate Hexane Ethanol Formamidine acetate Sodium sulfate Sodium FORMAMIDINE HYDROCHLORIDE Ethyl acetate Hydrochloric acid Methanol

Preparation Products

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4-Hydroxy-6-(trifluoromethyl)pyrimidine Suppliers

China 149 France 1 Germany 2 India 4 Japan 1 Switzerland 3 United Kingdom 1 United States 16 Global 177

Creasyn Finechem(Tianjin) Co., Ltd.

Tel: 022-022-83946278 13820372920
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J & K SCIENTIFIC LTD.

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Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
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Advantage: 62

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
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TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
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Energy Chemical

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Capot Chemical Co., Ltd

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Nanjing Habo Medical Technology Co., Ltd.

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Pure Chemistry Scientific Inc.

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Country: United States
ProdList: 10194
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View Lastest Price from 4-Hydroxy-6-(trifluoromethyl)pyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 4-Hydroxy-6-(trifluoromethyl)pyrimidine 1546-78-7
Price: US $1.00-900.00/KG
Min. Order: 1g
Purity: 98%
Supply Ability: 50ton
Release date: 2020-05-15

Henan Aochuang Chemical Co.,Ltd.

Product: 4-Hydroxy-6-(trifluoromethyl)pyrimidine 1546-78-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-28

Dideu Industries Group Limited

Product: 4-Hydroxy-6-(trifluoromethyl)pyrimidine 1546-78-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-06

1546-78-7, 4-Hydroxy-6-(trifluoromethyl)pyrimidineRelated Search:

CHLOROPHOSPHONAZO III Benzotrifluoride Lithium trifluoromethanesulfonate 4-Aminobenzotrifluoride 4-Ethyl-5-fluoro-6-hydroxypyrimidine 4-Hydroxypyrimidine 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL (Trifluoromethyl)trimethylsilane 4,6-Dihydroxypyrimidine Pirimiphos-methyl Trifluoromethanesulfonic acid Trifluridine 4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE 4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE-2-THIOL 2-Hydroxy-4-(trifluoromethyl)pyrimidine ETHYL 4-HYDROXY-2-(TRIFLUOROMETHYL)PYRIMIDINE-5-CARBOXYLATE 4-Hydroxy-2-(trifluoromethyl)pyrimidine 2-AMINO-4-HYDROXY-6-(TRIFLUOROMETHYL)PYRIMIDINE

6-TRIFLUOROMETHYL-4-PYRIMIDINOL

6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL

4-HYDROXY-6-TRIFLUOROMETHYLPYRIMIDINE

4-PYRIMIDINOL, 6-(TRIFLUOROMETHYL)-

4-Hydroxy-6-(trifluormethyl)-pyrimidin

6-TRIFLUOROMETHYL-4-PYRIMIDINOL 98+%

6-Trifluoromethyl-4(1H)-pyrimidinone

4-Hydroxy-6-(trifluoromethyl)pyrimidine ,98%

4(3H)-PyriMidinone, 6-(trifluoroMethyl)-

4-Hydroxy-6-(trifluoromethyl)pyrimidine 6-(Trifluoromethyl)pyrimidin-4-ol

4-Hydroxy-6-(trifluoromethyl)pyrimidine 99%

6-(trifluoromethyl)pyrimidin-4(3H)-one

6-trifluoromethyl-4-hydroxypyrimidine

6-(trifluoromethyl)-1H-pyrimidin-4-one

4-Hydroxy-6-(trifluoromethyl)pyrimidine ISO 9001：2015 REACH

6-(Trifluoromethyl)-4(3H)-pyrimidinone

1546-78-7

Heterocyclic Building Blocks

Pyrimidines

Building Blocks

Boronic Acid

Heterocyclic Compounds

Fluorinated pyrimidine derivatives

Pyrimidines

Pyrimidine series

alcohol

Fluorine series