ChemicalBook > CAS DataBase List > 4-Hydroxy-6-(trifluoromethyl)pyrimidine

4-Hydroxy-6-(trifluoromethyl)pyrimidine

Product Name
4-Hydroxy-6-(trifluoromethyl)pyrimidine
CAS No.
1546-78-7
Chemical Name
4-Hydroxy-6-(trifluoromethyl)pyrimidine
Synonyms
6-TRIFLUOROMETHYL-4-PYRIMIDINOL;6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL;4-PYRIMIDINOL, 6-(TRIFLUOROMETHYL)-;6-Trifluoromethyl-4(1H)-pyrimidinone;6-TRIFLUOROMETHYL-4-PYRIMIDINOL 98+%;4-HYDROXY-6-TRIFLUOROMETHYLPYRIMIDINE;6-trifluoromethyl-4-hydroxypyrimidine;4-Hydroxy-6-(trifluormethyl)-pyrimidin;6-(trifluoromethyl)pyrimidin-4(3H)-one;6-(trifluoromethyl)-1H-pyrimidin-4-one
CBNumber
CB5488081
Molecular Formula
C5H3F3N2O
Formula Weight
164.09
MOL File
1546-78-7.mol
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4-Hydroxy-6-(trifluoromethyl)pyrimidine Property

Melting point:
169-171 °C(lit.)
Boiling point:
130.3±50.0 °C(Predicted)
Density 
1.55±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
6.41±0.40(Predicted)
form 
Crystalline
color 
White
Water Solubility 
Solubility in methanol (almost transparency). Slightly soluble in water.
BRN 
145548
CAS DataBase Reference
1546-78-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29335990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
385344
Product name
4-Hydroxy-6-(trifluoromethyl)pyrimidine
Purity
99%
Packaging
1g
Price
$43.3
Updated
2023/01/07
TCI Chemical
Product number
T1601
Product name
6-Trifluoromethyl-4-pyrimidinol
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$36
Updated
2024/03/01
TCI Chemical
Product number
T1601
Product name
6-Trifluoromethyl-4-pyrimidinol
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$129
Updated
2024/03/01
Alfa Aesar
Product number
H64381
Product name
4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%
Packaging
1g
Price
$31.4
Updated
2023/06/20
Alfa Aesar
Product number
H64381
Product name
4-Hydroxy-6-(trifluoromethyl)pyrimidine, 97%
Packaging
5g
Price
$141
Updated
2023/06/20
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4-Hydroxy-6-(trifluoromethyl)pyrimidine Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

4-Hydroxy-6-(trifluoromethyl)pyrimidine (6-(Trifluoromethyl)-4-pyrimidinol) may be used in the synthesis of 10-[3-(6-trifluoromethyl-pyrimidin-4-yloxy)-propoxy]-(20S)-camptothecin.

Uses

4-Hydroxy-6-(trifluoromethyl)pyrimidine is used as building block in chemical synthesis. Attributes Development Product Contact

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 5744, 1958 DOI: 10.1021/ja01554a041

General Description

4-Hydroxy-6-(trifluoromethyl)pyrimidine, a pyrimidine derivative, is a heterocyclic building block.

4-Hydroxy-6-(trifluoromethyl)pyrimidine Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Hydroxy-6-(trifluoromethyl)pyrimidine Suppliers

Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-83946278 13820503911
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
978
Advantage
68
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
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81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
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Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Nanjing Habo Medical Technology Co., Ltd.
Tel
025-85760892 13376090521
Fax
025-85766769
Email
sales@habotech.com
Country
China
ProdList
979
Advantage
60
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
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View Lastest Price from 4-Hydroxy-6-(trifluoromethyl)pyrimidine manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
4-Hydroxy-6-(trifluoromethyl)pyrimidine 1546-78-7
Price
US $1.00-900.00/KG
Min. Order
1g
Purity
98%
Supply Ability
50ton
Release date
2020-05-15
Henan Aochuang Chemical Co.,Ltd.
Product
4-Hydroxy-6-(trifluoromethyl)pyrimidine 1546-78-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-28
Dideu Industries Group Limited
Product
4-Hydroxy-6-(trifluoromethyl)pyrimidine 1546-78-7
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-06

1546-78-7, 4-Hydroxy-6-(trifluoromethyl)pyrimidineRelated Search:


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  • 6-(TRIFLUOROMETHYL)PYRIMIDIN-4-OL
  • 4-HYDROXY-6-TRIFLUOROMETHYLPYRIMIDINE
  • 4-PYRIMIDINOL, 6-(TRIFLUOROMETHYL)-
  • 4-Hydroxy-6-(trifluormethyl)-pyrimidin
  • 6-TRIFLUOROMETHYL-4-PYRIMIDINOL 98+%
  • 6-Trifluoromethyl-4(1H)-pyrimidinone
  • 4-Hydroxy-6-(trifluoromethyl)pyrimidine ,98%
  • 4(3H)-PyriMidinone, 6-(trifluoroMethyl)-
  • 4-Hydroxy-6-(trifluoromethyl)pyrimidine 6-(Trifluoromethyl)pyrimidin-4-ol
  • 4-Hydroxy-6-(trifluoromethyl)pyrimidine 99%
  • 6-(trifluoromethyl)pyrimidin-4(3H)-one
  • 6-trifluoromethyl-4-hydroxypyrimidine
  • 6-(trifluoromethyl)-1H-pyrimidin-4-one
  • 4-Hydroxy-6-(trifluoromethyl)pyrimidine ISO 9001:2015 REACH
  • 6-(Trifluoromethyl)-4(3H)-pyrimidinone
  • 1546-78-7
  • Heterocyclic Building Blocks
  • Pyrimidines
  • Building Blocks
  • Boronic Acid
  • Heterocyclic Compounds
  • Fluorinated pyrimidine derivatives
  • Pyrimidines
  • Pyrimidine series
  • alcohol
  • Fluorine series