ChemicalBook > CAS DataBase List > 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one

Product Name
5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
CAS No.
885-70-1
Chemical Name
5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
Synonyms
5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;LS 75;Pirenzepine EP Impurity B;11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one;5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE;5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one;1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one;5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-;6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro-
CBNumber
CB5488339
Molecular Formula
C12H9N3O
Formula Weight
211.22
MOL File
885-70-1.mol
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5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Property

Melting point:
292-293℃
Boiling point:
336℃
Density 
1.275
Flash point:
157℃
storage temp. 
Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
Solid
pka
11.58±0.20(Predicted)
color 
Light Beige to Beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
D446720
Product name
5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Packaging
2.5g
Price
$105
Updated
2021/12/16
Matrix Scientific
Product number
070862
Product name
5,6-Dihydro-6-oxo-11H-pyrido-[2,3-b][1,4]benzodiazepine
Purity
98%
Packaging
25g
Price
$208
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0165648
Product name
5,11-DIHYDROPYRIDO[2,3-BETA][1,4]BENZODIAZEPIN-6-ONE
Purity
95.00%
Packaging
25G
Price
$1268.19
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0165648
Product name
5,11-DIHYDROPYRIDO[2,3-BETA][1,4]BENZODIAZEPIN-6-ONE
Purity
95.00%
Packaging
5L
Price
$6462.5
Updated
2021/12/16
Matrix Scientific
Product number
070862
Product name
5,6-Dihydro-6-oxo-11H-pyrido-[2,3-b][1,4]benzodiazepine
Purity
98%
Packaging
1g
Price
$30
Updated
2021/12/16
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5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Chemical Properties,Usage,Production

Uses

5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one, can be used in the synthesis of fluorescent pirenzepine derivatives, used as potential bitopic ligands of the Human M1 Muscarinic receptor.

Synthesis


In a 1000 ml reaction flask,Add 600 ml of butanol,100 g of 2-amino-N- (2-chloropyridyl-3-yl) benzamide,2 ml of concentrated sulfuric acid,The reaction was refluxed for 3 hours at a reaction temperature of 80 ?? C,Cooled to room temperature,filter,Washed with acetone,50-60 ?? C in vacuo to give 98 g of a pale yellow solid product,Yield 98percent, purity 99percent.

5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one Preparation Products And Raw materials

Raw materials

Stannous chloride dihydrate N-(2-CHLOROPYRIDIN-3-YL)-2-NITROBENZAMIDE 2-Chloro-3-pyridinamine 2-Nitrobenzoyl chloride

Preparation Products

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View Lastest Price from 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one manufacturers

Career Henan Chemical Co
Product
2-CHLORO-4-FLUORO-5-METHYL ANILINE 116759-33-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-14
Career Henan Chemical Co
Product
5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE 885-70-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-14

885-70-1, 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-oneRelated Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate 11-[[4-[4-(DIETHYLAMINO)BUTYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE BIBN 99 5,11-Dihydro-11-chloroacetyl-6H-pyrido[2,3-b][1,4]benzodiazepine-6-one Pirenzepine AF-DX 384 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one 6H-Pyrido(2,3-b)(1,4)benzodiazepin-6-one, 5,11-dihydro-11-(1H-imidazol -1-ylacetyl)-, hydrate Pirenzepine hydrochloride tripitramine 11-[[2-[(DIETHYLAMINO)METHYL]-1-PIPERIDINYL]ACETYL]-5,11-DIHYDRO-6H-PYRIDO[2,3-B][1,4]BENZODIAZEPIN-6-ONE PIRENZEPINE, [N-METHYL-3H]- AF-DX 384, [2,3-DIPROPYLAMINO-3H]-

  • 5H-BENZO[E]PYRIDO[3,2-B][1,4]DIAZEPIN-6(11H)-ONE
  • 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
  • LS 75
  • 11H-Pyrido[2,3-b][1,4]benzodiazepine-6(5H)-one
  • 5,11-dihydropyrido[2,3-b][1,4]benzodiazepin-6-one
  • 5,11-Dihydropyrido[2,3-b][1,4]benzodiazepin-6-one AK-36728
  • 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one, 1,5-dihydro-
  • 6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-
  • 1,5-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
  • 5,6-Dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine
  • Pirenzepine EP Impurity B
  • 885-70-1