Chlorguanide Hydrochloride
- Product Name
- Chlorguanide Hydrochloride
- CAS No.
- 637-32-1
- Chemical Name
- Chlorguanide Hydrochloride
- Synonyms
- m4888;3359rp;diguanyl;Paludrin;sn12,837;Chlorguanid;Chloroquanil;Proguanil HCL;ChlorguanideHCl;PROGUANIL HCL IP/BP
- CBNumber
- CB5488955
- Molecular Formula
- C11H17Cl2N5
- Formula Weight
- 290.19
- MOL File
- 637-32-1.mol
Chlorguanide Hydrochloride Property
- Melting point:
- 249-2510C
- storage temp.
- 2-8°C
- solubility
- acetonitrile: water: ~1mg/mL (60/40)
- form
- solid
N-Bromosuccinimide Price
- Product number
- G7048
- Product name
- Proguanil hydrochloride
- Purity
- ≥95% (HPLC)
- Packaging
- 10mg
- Price
- $90
- Updated
- 2024/03/01
- Product number
- 1568040
- Product name
- Proguanil hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $393
- Updated
- 2024/03/01
- Product number
- BP297
- Product name
- Proguanil hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $221
- Updated
- 2023/06/20
- Product number
- PHR1713
- Product name
- Proguanil hydrochloride
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 1g
- Price
- $173
- Updated
- 2024/03/01
- Product number
- G7048
- Product name
- Proguanil hydrochloride
- Purity
- ≥95% (HPLC)
- Packaging
- 50mg
- Price
- $341
- Updated
- 2024/03/01
Chlorguanide Hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug.
Uses
Chlorguanide Hydrochloride can be intended for use as an internal standard for the quantification of Proguanil by GC- or LC-mass spectrometry.
brand name
Paludrine (Zeneca).
General Description
Proguanil hydrochloride is a biguanide compound, widely used as an antimalarial drug. It exhibits sporontocidal activity, thereby rendering the gametocytes non-infective to the mosquito vector.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Biochem/physiol Actions
Chlorguanide (proguanil) is combined with atovaquone for malaria prophylaxis. The two compounds act synergistically to inhibit the plasmodial dihydrofolate reductase (DHFR) and interrupt the electron transport chain. Mutations in DHFR account for the development of resistant strains.
Chlorguanide Hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Chlorguanide Hydrochloride manufacturers
- Product
- Chlorguanide Hydrochloride 637-32-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-17