ChemicalBook > CAS DataBase List > Chlorguanide Hydrochloride

Chlorguanide Hydrochloride

Product Name
Chlorguanide Hydrochloride
CAS No.
637-32-1
Chemical Name
Chlorguanide Hydrochloride
Synonyms
m4888;3359rp;diguanyl;Paludrin;sn12,837;Chlorguanid;Chloroquanil;Proguanil HCL;ChlorguanideHCl;PROGUANIL HCL IP/BP
CBNumber
CB5488955
Molecular Formula
C11H17Cl2N5
Formula Weight
290.19
MOL File
637-32-1.mol
More
Less

Chlorguanide Hydrochloride Property

Melting point:
249-2510C
storage temp. 
2-8°C
solubility 
acetonitrile: water: ~1mg/mL (60/40)
form 
solid
color 
White to off-white
Water Solubility 
acetonitrile: water: ~1mg/mL (60/40)
More
Less

Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
3249
WGK Germany 
3
RTECS 
DU1750000
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
2925294500
Toxicity
LD50 orally in rats: 200 mg/kg (Schmidt)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G7048
Product name
Proguanil hydrochloride
Purity
≥95% (HPLC)
Packaging
10mg
Price
$92.5
Updated
2025/07/31
Sigma-Aldrich
Product number
BP297
Product name
Proguanil hydrochloride
Purity
British Pharmacopoeia (BP) Reference Standard
Packaging
100MG
Price
$208
Updated
2025/07/31
Sigma-Aldrich
Product number
1568040
Product name
Proguanil hydrochloride
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
200mg
Price
$367
Updated
2025/07/31
Sigma-Aldrich
Product number
PHR1713
Product name
Proguanil hydrochloride
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
1g
Price
$176.7
Updated
2025/07/31
Sigma-Aldrich
Product number
G7048
Product name
Proguanil hydrochloride
Purity
≥95% (HPLC)
Packaging
50mg
Price
$351
Updated
2025/07/31
More
Less

Chlorguanide Hydrochloride Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Proguanil (chlorguanide) may be used in anti-parasitic protozoan drug development to study its pharmacokinetics, metabolism, safety, efficacy and methods of delivery as an antimalarial drug.

Uses

Chlorguanide Hydrochloride can be intended for use as an internal standard for the quantification of Proguanil by GC- or LC-mass spectrometry.

brand name

Paludrine (Zeneca).

General Description

Proguanil hydrochloride is a biguanide compound, widely used as an antimalarial drug. It exhibits sporontocidal activity, thereby rendering the gametocytes non-infective to the mosquito vector.
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Biochem/physiol Actions

Chlorguanide (proguanil) is combined with atovaquone for malaria prophylaxis. The two compounds act synergistically to inhibit the plasmodial dihydrofolate reductase (DHFR) and interrupt the electron transport chain. Mutations in DHFR account for the development of resistant strains.

Chlorguanide Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Chlorguanide Hydrochloride Suppliers

Canada 4 China 60 Europe 2 France 2 Germany 1 India 42 Israel 1 Norway 1 Philippines 1 Poland 1 Switzerland 1 United Arab Emirates 1 United Kingdom 7 United States 14 Global 138
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai TaoSu Biochemical Technology Co., Ltd.
Tel
021-33632979
Fax
021-34692979
Email
info@tsbiochem.com
Country
China
ProdList
8065
Advantage
58
Jinan Mingya Medical Technology Co., Ltd.
Tel
0531-85828981
Fax
+86-531-85806006
Email
864598798@qq.com
Country
China
ProdList
588
Advantage
58
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3506
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 0086-15250997978
Fax
025-58362220
Email
sale@njxizebio.com
Country
China
ProdList
4855
Advantage
55
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
17801761073
Email
3193328036@qq.com
Country
China
ProdList
6338
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.
Tel
027-50664929, 13971561712
Fax
027-50664927 / QQ: 3452835437
Email
hubxys2001@163.com
Country
China
ProdList
1437
Advantage
55
Aikon International Limited
Tel
025-58851090 15955137747
Fax
(6)02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
15949
Advantage
58
Conier Chem & Pharma Limited
Tel
13368167990
Email
sales@conier.com
Country
China
ProdList
185
Advantage
58
Angel Pharmatech, Ltd.
Tel
17317130613
Fax
QQ3358272972
Email
3358272972@qq.com
Country
China
ProdList
3276
Advantage
58
Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.
Tel
029-88380327 17691182729
Fax
029-88380327
Email
1018@dideu.com
Country
China
ProdList
2011
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 +86-13028896684;
Email
sales@rrkchem.com
Country
China
ProdList
57422
Advantage
58
Xi'an MC Biotech, Co., Ltd.
Tel
029-89275612 +8618991951683
Fax
8618991951683
Email
mcbio_sales@163.com
Country
China
ProdList
2251
Advantage
58
Dideu Industries Group Limited
Tel
+86-29-89586680 +86-15129568250
Email
1026@dideu.com
Country
China
ProdList
20284
Advantage
58
AFINE CHEMICALS LIMITED
Tel
+86-0571-85134551
Fax
008657185134895
Email
sales@afinechem.com
Country
China
ProdList
15109
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Guangzhou Dreampharm Biotechnology Co., Ltd.
Tel
020-36607679 19925672674
Fax
QQ 3008233717
Email
3008233746@qq.com
Country
China
ProdList
9883
Advantage
12
Guangzhou Younan Technology Co., Ltd
Tel
020-82000279 18988941452
Fax
QQ：3283937693
Email
YN_research@163.com
Country
China
ProdList
3011
Advantage
58
Shanghai Luofa Biochemical Technology Co., Ltd.
Tel
021-51111890 15317326293
Email
sales@molnova.com
Country
China
ProdList
4195
Advantage
58
Chongqing Kangzhou Zhitong Pharmaceutical Technology Co., Ltd.
Tel
173-08362167 17308362167
Email
3090602484@qq.com
Country
China
ProdList
568
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing@energy-chemical.com
Country
China
ProdList
44918
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
13675144456
Fax
025-85563444
Email
sean.lv@synzest.com
Country
China
ProdList
10784
Advantage
58
Guangzhou Juntang Technology Co., Ltd
Tel
020-36607679 13502246435
Email
sales@dmstandards.com
Country
China
ProdList
10945
Advantage
58
cjbscvictory
Tel
13348960310
Email
3003867561@qq.com
Country
China
ProdList
10503
Advantage
58
Zhuhai Anzhe Biotechnology Co,Ltd.
Tel
13169972583
Email
513211116@qq.com
Country
China
ProdList
3005
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
Advantage
58
Hubei wei shi reagent group ltd., company
Tel
027-59102966 18717199209
Fax
027-59379337
Email
2853877583@qq.com
Country
China
ProdList
2715
Advantage
58
Henan Kehong Biological Technology Co. LTD
Tel
0371-86658258 ；0371-55969461
Fax
QQ：3311217266
Email
info@kehobio.com
Country
China
ProdList
2575
Advantage
58
Gongyishengan Technology (Shenzhen) Co., Ltd.
Tel
0755-89218110 13480856786
Email
2880189130@qq.com
Country
China
ProdList
991
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24961
Advantage
58
LGC Science (Shanghai) Ltd.
Tel
17717235263
Email
cindy.yang@lgcgroup.com
Country
China
ProdList
18003
Advantage
58
Jiaxing Deyi Chemical Co., Ltd
Tel
0573-85866609 13588473046
Email
824930988@qq.com
Country
China
ProdList
7865
Advantage
58
Nantong QuanYi Biotechnology Co., Ltd
Tel
0513-66337626 18051384581
Email
sales@chemhifuture.com
Country
China
ProdList
5929
Advantage
58
guoyungurui
Tel
18162595016; 18162595016
Email
3287908757@qq.com
Country
China
ProdList
10335
Advantage
58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12000
Advantage
58
Sangon Biotech (Shanghai) Co.,Ltd.
Tel
400-821-026
Email
Sales@sangon.com
Country
China
ProdList
6710
Advantage
58
Merck KGaA
Tel
21-20338288
Email
ordercn@merckgroup.com
Country
China
ProdList
6394
Advantage
58
Biosynth Biological Technology (Suzhou) Co Ltd
Tel
51288865780
Email
sales@biosynth.com
Country
China
ProdList
6051
Advantage
58
Selleck Chemicals
Tel
400-668-6834
Email
info@selleck.cn
Country
China
ProdList
6071
Advantage
58
Santa Cruz Biotechnology Inc
Tel
021-60936350
Email
scbt@scbt.com
Country
China
ProdList
6594
Advantage
58
Chongqing jooe co., ltd
Tel
+undefined86-15223382610
Email
info@jooe.com
Country
China
ProdList
6208
Advantage
58
Suzhou ARTK Medchem Co., Ltd.
Tel
+86-512-68323658 +86-18168183658
Email
sales1@artkmedchem.com
Country
China
ProdList
39002
Advantage
58
Guangzhou Taozhu Biotechnology Co., Ltd
Tel
4008200310
Country
CHINA
ProdList
111
Advantage
58
Absin Bioscience Inc.
Tel
--
Fax
--
Email
chenjw@absin.cn
Country
CHINA
ProdList
6208
Advantage
58
Proteintech China
Tel
--
Fax
--
Email
Proteintech-CN@ptglab.com
Country
CHINA
ProdList
6290
Advantage
58
More
Less

View Lastest Price from Chlorguanide Hydrochloride manufacturers

Dideu Industries Group Limited
Product
Chlorguanide Hydrochloride 637-32-1
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons Min
Release date
2021-06-17

637-32-1, Chlorguanide HydrochlorideRelated Search:

Proguanil Related Compound D (25 mg) (1,5-bis(1-methylethyl)biguanide hydrochloride) 1-(3-Chlorophenyl)-5-isopropylbiguanide Hydrochloride Proguanil Related Compound C (25 mg) (1,5-bis(4-chlorophenyl)biguanide hydrochloride) 1-Cyano-3-isopropylguanidine Levetiracetam Gemfibrozil GEMFIBROZIL RELATED COMPOUND A (20 MG) (2,2-DIMETHYL-5-[2,5-DIMETHYL-4-(PROPENE-1-YL)PHE-NOXY]VALERIC ACID) PROGUANIL HYDROCHLORIDE - REFERENCE SPECTRUM PROGUANIL HYDROCHLORIDE IMP. B (EP): 4-CHLOROANILINE GEMFIBROZIL IMPURITY A PROGUANIL HYDROCHLORIDE 1-(4-CHLOROPHENYL)BIGUANIDE HYDROCHLORIDE N-(4-CHLOROPHENYL)-N'-(ISOPROPYL)-IMIDODICARBONIMIDIC DIAMIDE Chlorguanide Hydrochloride

  • 1-(p-chlorophenyl)-5-isopropylbiguanidehydrochloride
  • N1-(4-Chlorophenyl)-N5-isopropylbiguanide Hydrochloride
  • 1-(p-chlorophenyl)-5-isopropyl-biguanidmonohydrochloride
  • 3359rp
  • chlorguanidehydrochloride
  • chloroguanidehydrochloride
  • chloroguanidinehydrochloride
  • diguanyl
  • drinupalhydrochloride
  • Chlorguanid
  • N-(4-Chlorophenyl)-N'-(1-methylethyl)-imidodicarbonimidic Diamide Hydrochloride
  • Paludrin
  • Chlorguanide Hydrochloride3
  • N1-(4-Chlorophenyl)-N5-isopropylbiguanide
  • PROGUANIL HYDROCHLORIDE###N-(4-CHLOROPHENYL)-N'-(ISOPROPYL)-IMIDODICARBONIMIDIC DIAMIDE
  • guanatolhydrochloride
  • m4888
  • n-4-chlorophenyl-n(sup5)-isopropyldiguanidehydrochloride
  • paludrinehydrochloride
  • palusilhydrochloride
  • sn12,837
  • PROGUANIL HYDROCHLORIDE
  • Biguanide, 1-(p-chlorophenyl)-5-isopropyl-, monohydrochloride
  • Chloroquanil
  • Proguanil Hydrochloride (200 mg)
  • IMidodicarboniMidic diaMide, N-(4-chlorophenyl)-N'-(1-Methylethyl) -, Hydrochloride (1:1)
  • Proguanil HCL
  • ChlorguanideHCl
  • Proguanil for system suitability
  • 1-(4-Chlorophenyl)-5-(1-methylethyl)biguanide hydrochloride
  • Chlorguanide Hydrochloride USP/EP/BP
  • Proguanil Hydrochloride (1568040)
  • Proguanil hydrochloride,Proguanil,infection,biguanide,Inhibitor,embryotoxicity,toxicity,inhibit,Parasite,reproductive,antimalarial,Antifolate
  • Imidodicarbonimidic diamide, N-(4-chlorophenyl)-N'-(1-methylethyl)-,monohydrochloride
  • PROGUANIL HCL IP/BP
  • Proguanil hydrochloride, 10 mM in DMSO
  • Proguanil HCl(Atovaquone)
  • 637-32-1
  • C11H16ClN5HCl
  • C11H17Cl2N5
  • Aromatics
  • Bases & Related Reagents
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • PALUDRINE